8SMS
 
 | | Crosslinked Crystal Structure of Type II Fatty Acid Synthase, FabB, and cerulenin crosslinker-crypto Acyl Carrier Protein, AcpP | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(2R)-2-hydroxy-4-oxododecanamido]ethyl}-beta-alaninamide | | 著者 | Jiang, Z, Chen, A, Chen, J, Sekhon, A, Louie, G.V, Noel, J.P, La Clair, J.J, Burkart, M.D. | | 登録日 | 2023-04-26 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Masked cerulenin enables a dual-site selective protein crosslink.
Chem Sci, 14, 2023
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5JO7
 | | Henbane premnaspirodiene synthase (HPS), also known as Henbane vetispiradiene synthase (HVS) from Hyoscyamus muticus | | 分子名称: | Vetispiradiene synthase 1 | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-05-02 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Functional study of terpene synthase from 512 mutant library of henbane premnaspirodiene synthase reveals protein residue interactions
To Be Published
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4R1T
 | | Crystal structure of Petunia hydrida cinnamoyl-CoA reductase | | 分子名称: | cinnamoyl CoA reductase, molecular iodine | | 著者 | Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K. | | 登録日 | 2014-08-07 | | 公開日 | 2014-10-01 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
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6N10
 | | Crystal structure of Arabidopsis thaliana mevalonate 5-diphosphate decarboxylase 1 complexed with (R)-MVAPP | | 分子名称: | (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase MVD1, peroxisomal, ... | | 著者 | Noel, J.P, Thomas, S.T, Louie, G.V. | | 登録日 | 2018-11-07 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase.
Acs Chem.Biol., 14, 2019
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6N0Z
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6N0X
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6N0Y
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5BUL
 | | Structure of flavin-dependent brominase Bmp2 triple mutant Y302S F306V A345W | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, flavin-dependent halogenase triple mutant | | 著者 | Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S. | | 登録日 | 2015-06-04 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9784 Å) | | 主引用文献 | Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5BUK
 | | Structure of flavin-dependent chlorinase Mpy16 | | 分子名称: | FADH2-dependent halogenase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | | 著者 | Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S. | | 登録日 | 2015-06-03 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5BVA
 | | Structure of flavin-dependent brominase Bmp2 | | 分子名称: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, flavin-dependent halogenase | | 著者 | Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S. | | 登録日 | 2015-06-04 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.873 Å) | | 主引用文献 | Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4DOO
 | | Crystal structure of Arabidopsis thaliana fatty-acid binding protein At3g63170 (AtFAP1) | | 分子名称: | Chalcone-flavanone isomerase family protein, LAURIC ACID, POTASSIUM ION | | 著者 | Noel, J.P, Pojer, F, Louie, G.V, Bowman, M.E. | | 登録日 | 2012-02-09 | | 公開日 | 2012-05-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012
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4DOK
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4DOI
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4DOL
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5IK6
 | | Tobacco 5-epi-aristolochene synthase with germacrene A and PPi | | 分子名称: | 5-epi-aristolochene synthase, DIPHOSPHATE, GERMACRENE A, ... | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5IL3
 | | Tobacco 5-epi-aristolochene synthase with MOPSO buffer molecule and Mg2+ ions | | 分子名称: | (2R)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, (2S)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILH
 | | Tobacco 5-epi-aristolochene synthase with CAPSO buffer molecule and Ca2+ ions | | 分子名称: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5IK0
 | | Tobacco 5-epi-aristolochene synthase with FPP | | 分子名称: | 5-epi-aristolochene synthase, FARNESYL DIPHOSPHATE, MAGNESIUM ION | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5IK9
 | | Tobacco 5-epi-aristolochene with farnesyl monophosphate | | 分子名称: | (2E,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl dihydrogen phosphate, 5-epi-aristolochene synthase, MAGNESIUM ION | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5ILI
 | | Tobacco 5-epi-aristolochene synthase with CAPSO buffer molecule and Mg2+ ions | | 分子名称: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILD
 | | Tobacco 5-epi-aristolochene synthase with MES buffer molecule and Mg2+ ions | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-epi-aristolochene synthase, MAGNESIUM ION | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5IM1
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5IKH
 | | Tobacco 5-epi-aristolochene synthase M4 mutant with (-)-premnaspirodiene | | 分子名称: | (2R,5S,10R)-6,10-dimethyl-2-(prop-1-en-2-yl)spiro[4.5]dec-6-ene, 5-epi-aristolochene synthase, MAGNESIUM ION | | 著者 | Koo, H.J, O'Maille, P.E, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5IL8
 | | Tobacco 5-epi-aristolochene synthase with MOPSO buffer molecule and Ca2+ ions | | 分子名称: | (2R)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, (2S)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILJ
 | | Tobacco 5-epi-aristolochene synthase with BIS-TRIS buffer molecule | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-epi-aristolochene synthase | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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