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9YM4
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BU of 9ym4 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with beta3Phe at Position 6
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YM3
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BU of 9ym3 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with ACPC at Position 30
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YM5
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BU of 9ym5 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with Calpha-methyl-Phe at Position 6
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YM0
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BU of 9ym0 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with ACPC at Position 28
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YM6
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BU of 9ym6 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with Calpha-methyl-Phe at Position 17
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YM1
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BU of 9ym1 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with beta3Lys at Position 29
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YLZ
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BU of 9ylz by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with beta3Leu at Position 28
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YM2
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BU of 9ym2 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with ACPC at Position 29
Descriptor: Villin-1
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
9YM7
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BU of 9ym7 by Molmil
Backbone Modification in the Villin Headpiece Miniprotein: HP35 with Calpha-methyl-Phe at Positions 6 and 17, ACPC at Position 29
Descriptor: Villin-1 headpiece: Met12Nle, Phe6alphaMePhe, Phe17alphaMePhe, ...
Authors:Lin, Y, David, R.M, Amin, D.M, Osborne, S.W.J, Horne, W.S.
Deposit date:2025-10-09
Release date:2026-01-07
Last modified:2026-02-25
Method:SOLUTION NMR
Cite:Backbone engineering in the hydrophobic core of villin headpiece.
Rsc Chem Biol, 7, 2026
6V6M
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BU of 6v6m by Molmil
Crystal structure of an inactive state of GMPPNP-bound RhoA
Descriptor: 1,4-DIETHYLENE DIOXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Lin, Y, Zheng, Y.
Deposit date:2019-12-05
Release date:2020-12-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Structure of an inactive conformation of GTP-bound RhoA GTPase.
Structure, 29, 2021
6V6U
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BU of 6v6u by Molmil
Crystal structure of RhoA-GDP with novel Switch I conformation
Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lin, Y, Zheng, Y.
Deposit date:2019-12-06
Release date:2020-12-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Structure of an inactive conformation of GTP-bound RhoA GTPase.
Structure, 29, 2021
6V6V
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BU of 6v6v by Molmil
Crystal structure of oncogenic RhoA mutant G14V complexed with GDP
Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lin, Y, Zheng, Y.
Deposit date:2019-12-06
Release date:2020-12-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of an inactive conformation of GTP-bound RhoA GTPase.
Structure, 29, 2021
8FPW
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BU of 8fpw by Molmil
Crystal structure of tumor related RhoA mutant A161V in complex with GDP
Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lin, Y, Zheng, Y.
Deposit date:2023-01-05
Release date:2024-06-05
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Tumor-derived RHOA mutants interact with effectors in the GDP-bound state.
Nat Commun, 15, 2024
8FPX
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BU of 8fpx by Molmil
Crystal structure of tumor related RhoA mutant A161P in complex with GDP
Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lin, Y, Zheng, Y.
Deposit date:2023-01-05
Release date:2024-06-05
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Tumor-derived RHOA mutants interact with effectors in the GDP-bound state.
Nat Commun, 15, 2024
9BB5
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BU of 9bb5 by Molmil
Backbone Modification in the GA Module of Protein PAB: ACPC residues at positions 22 and 26
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9BB7
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BU of 9bb7 by Molmil
Backbone Modification in the GA Module of Protein PAB: ACPC residues at positions 5 and 39, beta3 residue at position 26
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9BB1
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BU of 9bb1 by Molmil
Backbone Modification in the GA Module of Protein PAB: Wild-type Sequence
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9BB4
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BU of 9bb4 by Molmil
Backbone Modification in the GA Module of Protein PAB: beta3-residues at positions 23 and 26
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9BB3
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BU of 9bb3 by Molmil
Backbone Modification in the GA Module of Protein PAB: beta3-residues at positions 22 and 26
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9BB2
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BU of 9bb2 by Molmil
Backbone Modification in the GA Module of Protein PAB: beta3-residues at positions 20 and 24
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9BB6
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BU of 9bb6 by Molmil
Backbone Modification in the GA Module of Protein PAB: ACPC residues at positions 5 and 13, beta3 residue at position 9
Descriptor: Peptostreptococcal albumin-binding protein
Authors:Lin, Y, Horne, W.S.
Deposit date:2024-04-05
Release date:2024-06-05
Last modified:2024-08-21
Method:SOLUTION NMR
Cite:Backbone Modification in a Protein Hydrophobic Core.
Chemistry, 30, 2024
9WXV
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BU of 9wxv by Molmil
Cryo-EM structure of TMEM63A-digitonin-cholesterol
Descriptor: CHOLESTEROL, Mechanosensitive cation channel TMEM63A
Authors:Lin, Y, Zhou, Z, Han, Y, Cheng, D, Wang, H, Ju, L, Zhang, Y, Cox, D.C, Corry, B.
Deposit date:2025-09-26
Release date:2026-02-11
Last modified:2026-04-08
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:TMEM63 proteins act as mechanically activated cholesterol modulated lipid scramblases contributing to membrane mechano-resilience.
Nat Commun, 17, 2026
5GCN
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BU of 5gcn by Molmil
CATALYTIC DOMAIN OF TETRAHYMENA GCN5 HISTONE ACETYLTRANSFERASE IN COMPLEX WITH COENZYME A
Descriptor: COENZYME A, HISTONE ACETYLTRANSFERASE GCN5
Authors:Lin, Y, Fletcher, C.M, Zhou, J, Allis, C.D, Wagner, G.
Deposit date:1999-03-24
Release date:1999-07-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A
Nature, 400, 1999
9JKQ
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BU of 9jkq by Molmil
Cryo-EM structure of the METH-bound hTAAR1-Gs complex
Descriptor: (2S)-N-methyl-1-phenylpropan-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Lin, Y, Wang, J, Shi, F.
Deposit date:2024-09-16
Release date:2024-10-16
Last modified:2025-07-23
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Molecular Mechanisms of Methamphetamine-Induced Addiction via TAAR1 Activation.
J.Med.Chem., 67, 2024
3CGR
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BU of 3cgr by Molmil
X-ray structure containing the pseudouridylated U2 snRNA and intron branch site consensus sequences
Descriptor: RNA (5'-R(*CP*GP*CP*AP*CP*UP*AP*AP*CP*CP*GP*CP*G)-3'), RNA (5'-R(*GP*CP*GP*CP*GP*GP*(PSU)P*AP*GP*UP*GP*C)-3'), SULFATE ION
Authors:Lin, Y, Kielkopf, C.L.
Deposit date:2008-03-06
Release date:2008-07-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structures of U2 snRNA-branchpoint duplexes containing conserved pseudouridines.
Biochemistry, 47, 2008

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