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8DHC
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BU of 8dhc by Molmil
Crystal structure of an i-motif from the HRAS promoter region
Descriptor: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, HRAS DNA
Authors:Yatsunyk, L.A, Li, K.S.
Deposit date:2022-06-27
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal Structure of an i-Motif from the HRAS Oncogene Promoter.
Angew.Chem.Int.Ed.Engl., 62, 2023
6I83
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BU of 6i83 by Molmil
Crystal structure of phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018366
Descriptor: 4-[5-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
Authors:Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M.
Deposit date:2018-11-19
Release date:2020-03-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase.
Acs Med.Chem.Lett., 11, 2020
6I82
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BU of 6i82 by Molmil
Crystal structure of partially phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018412
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ...
Authors:Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M.
Deposit date:2018-11-19
Release date:2020-03-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase.
Acs Med.Chem.Lett., 11, 2020
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