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1FC3
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BU of 1fc3 by Molmil
THE CRYSTAL STRUCTURE OF TRANS-ACTIVATION DOMAIN OF THE SPORULATION RESPONSE REGULATOR, SPO0A
Descriptor: SPO0A
Authors:Lewis, R.J, Krzywda, S, Wilkinson, A.J.
Deposit date:2000-07-17
Release date:2000-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The trans-activation domain of the sporulation response regulator Spo0A revealed by X-ray crystallography.
Mol.Microbiol., 38, 2000
1B0N
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BU of 1b0n by Molmil
SINR PROTEIN/SINI PROTEIN COMPLEX
Descriptor: PROTEIN (SINI PROTEIN), PROTEIN (SINR PROTEIN), ZINC ION
Authors:Lewis, R.J, Brannigan, J.A, Offen, W.A, Smith, I, Wilkinson, A.J.
Deposit date:1998-11-11
Release date:1999-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex.
J.Mol.Biol., 283, 1998
1QMP
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BU of 1qmp by Molmil
Phosphorylated aspartate in the crystal structure of the sporulation response regulator, Spo0A
Descriptor: CALCIUM ION, Stage 0 sporulation protein A
Authors:Lewis, R.J, Brannigan, J.A, Muchova, K, Barak, I, Wilkinson, A.J.
Deposit date:1999-10-04
Release date:1999-11-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Phosphorylated aspartate in the structure of a response regulator protein.
J. Mol. Biol., 294, 1999
1DZ3
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BU of 1dz3 by Molmil
DOMAIN-SWAPPING IN THE SPORULATION RESPONSE REGULATOR SPO0A
Descriptor: SULFATE ION, Stage 0 sporulation protein A
Authors:Lewis, R.J, Brannigan, J.A, Muchova, K, Leonard, G, Barak, I, Wilkinson, A.J.
Deposit date:2000-02-15
Release date:2000-04-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Domain swapping in the sporulation response regulator Spo0A.
J. Mol. Biol., 297, 2000
6GQA
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BU of 6gqa by Molmil
Cell division regulator S. pneumoniae GpsB
Descriptor: Cell cycle protein GpsB
Authors:Lewis, R.J, Rutter, Z.J.
Deposit date:2018-06-07
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes.
Nat Commun, 10, 2019
6GQN
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BU of 6gqn by Molmil
Cell division regulator, S. pneumoniae GpsB, in complex with peptide fragment of Penicillin Binding Protein PBP2a
Descriptor: Cell cycle protein GpsB, NICKEL (II) ION, SULFATE ION, ...
Authors:Lewis, R.J, Rutter, Z.J.
Deposit date:2018-06-07
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes.
Nat Commun, 10, 2019
4UXV
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BU of 4uxv by Molmil
Cytoplasmic domain of bacterial cell division protein EzrA
Descriptor: SEPTATION RING FORMATION REGULATOR EZRA
Authors:Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J.
Deposit date:2014-08-27
Release date:2014-10-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.961 Å)
Cite:Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis.
Nat.Commun., 5, 2014
1A39
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BU of 1a39 by Molmil
HUMICOLA INSOLENS ENDOCELLULASE EGI S37W, P39W DOUBLE-MUTANT
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I
Authors:Davies, G.J, Ducros, V, Lewis, R.J, Borchert, T.V, Schulein, M.
Deposit date:1998-01-28
Release date:1999-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Oligosaccharide specificity of a family 7 endoglucanase: insertion of potential sugar-binding subsites.
J.Biotechnol., 57, 1997
3ZKC
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BU of 3zkc by Molmil
Crystal structure of the master regulator for biofilm formation SinR in complex with DNA.
Descriptor: 5'-D(*AP*AP*AP*GP*TP*TP*CP*TP*CP*TP*TP*TP*AP*GP *AP*GP*AP*AP*CP*AP*AP)-3', 5'-D(*AP*TP*TP*GP*TP*TP*CP*TP*CP*TP*AP*AP*AP*GP *AP*GP*AP*AP*CP*TP*TP)-3', HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR
Authors:Newman, J.A, Rodrigues, C, Lewis, R.J.
Deposit date:2013-01-22
Release date:2013-03-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular Basis of the Activity of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis.
J.Biol.Chem., 288, 2013
3ZT9
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BU of 3zt9 by Molmil
The bacterial stressosome: a modular system that has been adapted to control secondary messenger signaling
Descriptor: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, SERINE PHOSPHATASE
Authors:Quin, M.B, Berrisford, J.M, Newman, J.A, Basle, A, Lewis, R.J, Marles-Wright, J.
Deposit date:2011-07-06
Release date:2012-02-22
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Bacterial Stressosome: A Modular System that Has Been Adapted to Control Secondary Messenger Signaling.
Structure, 20, 2012
3ZTA
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BU of 3zta by Molmil
The bacterial stressosome: a modular system that has been adapted to control secondary messenger signaling
Descriptor: ANTI-SIGMA-FACTOR ANTAGONIST (STAS) DOMAIN PROTEIN
Authors:Quin, M.B, Berrisford, J.M, Newman, J.A, Basle, A, Lewis, R.J, Marles-Wright, J.
Deposit date:2011-07-06
Release date:2012-02-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Bacterial Stressosome: A Modular System that Has Been Adapted to Control Secondary Messenger Signaling.
Structure, 20, 2012
7SKC
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BU of 7skc by Molmil
Solution structure of spider toxin Ssp1a
Descriptor: Ssp1a toxin
Authors:Wilson, D.T, Daly, N.L, Dongol, Y, Lewis, R.J.
Deposit date:2021-10-20
Release date:2022-02-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Voltage-Gated Sodium Channel Modulation by a New Spider Toxin Ssp1a Isolated From an Australian Theraphosid.
Front Pharmacol, 12, 2021
2VY9
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BU of 2vy9 by Molmil
Molecular architecture of the stressosome, a signal integration and transduction hub
Descriptor: ANTI-SIGMA-FACTOR ANTAGONIST
Authors:Marles-Wright, J, Grant, T, Delumeau, O, van Duinen, G, Firbank, S.J, Lewis, P.J, Murray, J.W, Newman, J.A, Quin, M.B, Race, P.R, Rohou, A, Tichelaar, W, van Heel, M, Lewis, R.J.
Deposit date:2008-07-21
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
Science, 322, 2008
7BN9
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BU of 7bn9 by Molmil
Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3
Descriptor: Penicillin-binding protein 3
Authors:Rao, V.A, Lewis, R.J.
Deposit date:2021-01-21
Release date:2022-03-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Cooperation between peptidoglycan transpeptidases and SEDS proteins in Bacillus subtilis cell division
To Be Published
2W47
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BU of 2w47 by Molmil
Clostridium thermocellum CBM35 in complex with delta-4,5- anhydrogalacturonic acid
Descriptor: 4-deoxy-beta-L-threo-hex-4-enopyranuronic acid-(1-4)-beta-D-galactopyranuronic acid, CALCIUM ION, LIPOLYTIC ENZYME, ...
Authors:Montainer, C, Lammerts van Bueren, A, Dumon, C, Flint, J.E, Correia, M.A, Prates, J.A, Firbank, S.J, Lewis, R.J, Grondin, G.G, Ghinet, M.G, Gloster, T.M, Herve, C, Knox, J.P, Talbot, B.G, Turkenburg, J.P, Kerovuo, J, Brzezinski, R, Fontes, C.M.G.A, Davies, G.J, Boraston, A.B, Gilbert, H.J.
Deposit date:2008-11-21
Release date:2009-01-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W87
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BU of 2w87 by Molmil
Xyl-CBM35 in complex with glucuronic acid containing disaccharide.
Descriptor: CALCIUM ION, ESTERASE D, UNKNOWN LIGAND, ...
Authors:Montainer, C, Bueren, A.L.v, Dumon, C, Flint, J.E, Correia, M.A, Prates, J.A, Firbank, S.J, Lewis, R.J, Grondin, G.G, Ghinet, M.G, Gloster, T.M, Herve, C, Knox, J.P, Talbot, B.G, Turkenburg, J.P, Kerovuo, J, Brzezinski, R, Fontes, C.M.G.A, Davies, G.J, Boraston, A.B, Gilbert, H.J.
Deposit date:2009-01-14
Release date:2009-01-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2VUJ
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BU of 2vuj by Molmil
Environmentally isolated GH11 xylanase
Descriptor: GH11 XYLANASE, GLYCEROL
Authors:Dumon, C, Varvak, A, Wall, M.A, Flint, J.E, Lewis, R.J, Lakey, J.H, Luginbuhl, P, Healey, S, Todaro, T, DeSantis, G, Sun, M, Parra-Gessert, L, Tan, X, Weiner, D.P, Gilbert, H.J.
Deposit date:2008-05-26
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
2VWJ
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BU of 2vwj by Molmil
Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography.
Descriptor: 5'-D(*AP*AP*UP*GP*GP*AP*GP*AP*CP*GP *GP*CP*TP*TP*TP*TP*GP*CP*CP*GP*TP*GP*TP*C)-3', DNA POLYMERASE, POTASSIUM ION
Authors:Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A.
Deposit date:2008-06-25
Release date:2008-07-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography.
J.Mol.Biol., 381, 2008
2W46
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BU of 2w46 by Molmil
CBM35 from Cellvibrio japonicus Abf62
Descriptor: CALCIUM ION, ESTERASE D, SODIUM ION
Authors:Montainer, C, Lammerts van Bueren, A, Dumon, C, Flint, J.E, Correia, M.A, Prates, J.A, Firbank, S.J, Lewis, R.J, Grondin, G.G, Ghinet, M.G, Gloster, T.M, Herve, C, Knox, J.P, Talbot, B.G, Turkenburg, J.P, Kerovuo, J, Brzezinski, R, Fontes, C.M.G.A, Davies, G.J, Boraston, A.B, Gilbert, H.J.
Deposit date:2008-11-21
Release date:2009-01-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W8D
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BU of 2w8d by Molmil
Distinct and essential morphogenic functions for wall- and lipo- teichoic acids in Bacillus subtilis
Descriptor: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE 2, ...
Authors:Schirner, K, Marles-Wright, J, Lewis, R.J, Errington, J.
Deposit date:2009-01-15
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Distinct and Essential Morphogenic Functions for Wall- and Lipo-Teichoic Acids in Bacillus Subtilis
Embo J., 28, 2009
2VWK
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BU of 2vwk by Molmil
Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. V93Q polymerase variant
Descriptor: DNA POLYMERASE, SODIUM ION, SULFATE ION
Authors:Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A.
Deposit date:2008-06-26
Release date:2008-07-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography.
J.Mol.Biol., 381, 2008
2VSI
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BU of 2vsi by Molmil
Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae
Descriptor: 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, 4-AMINO-1-{5-O-[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]-ALPHA-D-ARABINOFURANOSYL}PYRIMIDIN-2(1H)-ONE, CALCIUM ION
Authors:Baur, S, Marles-Wright, J, Buckenmaier, S, Lewis, R.J, Vollmer, W.
Deposit date:2008-04-23
Release date:2008-12-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Synthesis of Cdp-Activated Ribitol for Teichoic Acid Precursors in Streptococcus Pneumoniae.
J.Bacteriol., 191, 2009
2VPT
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BU of 2vpt by Molmil
Clostridium thermocellum family 3 carbohydrate esterase
Descriptor: CALCIUM ION, LIPOLYTIC ENZYME
Authors:Correia, M.A.S, Prates, J.A.M, Bras, J, Fontes, C.M.G.A, Newman, J.A, Lewis, R.J, Gilbert, H.J, Flint, J.E.
Deposit date:2008-03-04
Release date:2008-05-06
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structure of a Cellulosomal Family 3 Carbohydrate Esterase from Clostridium Thermocellum Provides Insights Into the Mechanism of Substrate Recognition
J.Mol.Biol., 379, 2008
7O61
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BU of 7o61 by Molmil
Crystal structure of the C-terminal PASTA domains of Staphylococcus aureus PBP1
Descriptor: Penicillin-binding protein 1
Authors:Rao, V.A, Lewis, R.J.
Deposit date:2021-04-09
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the C-terminal PASTA domains of Staphylococcus aureus PBP1
To Be Published
5OMT
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BU of 5omt by Molmil
Endonuclease NucB
Descriptor: NucB
Authors:Basle, A, Lewis, R.J.
Deposit date:2017-08-01
Release date:2017-11-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of NucB, a biofilm-degrading endonuclease.
Nucleic Acids Res., 46, 2018

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