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9GGC
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BU of 9ggc by Molmil
Structure of the G848S mutant of human mitochondrial DNA polymerase gamma
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-04-23
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 2025
9GGE
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BU of 9gge by Molmil
Structure of the A467T mutant of human mitochondrial DNA polymerase gamma
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-04-23
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 2025
9GGB
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BU of 9ggb by Molmil
Structure of the G848S mutant of human mitochondrial DNA polymerase gamma in complex with PZL-A
Descriptor: 1-[(4S)-8-chloranyl-3,4-dihydro-2H-chromen-4-yl]-3-(1-phenylpyrazol-3-yl)urea, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-04-23
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 2025
9GGF
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BU of 9ggf by Molmil
Structure of WT human mitochondrial DNA polymerase gamma
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-04-23
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 2025
9GGD
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BU of 9ggd by Molmil
Structure of the A467T mutant of human mitochondrial DNA polymerase gamma in complex with PZL-A
Descriptor: 1-[(4S)-8-chloranyl-3,4-dihydro-2H-chromen-4-yl]-3-(1-phenylpyrazol-3-yl)urea, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-08-13
Release date:2025-04-16
Last modified:2025-04-23
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Small molecules restore mutant mitochondrial DNA polymerase activity.
Nature, 2025
9G77
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BU of 9g77 by Molmil
Mouse mitochondrial DNA polymerase gamma ternary complex in error-editing conformer (composite)
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-07-19
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
9G74
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BU of 9g74 by Molmil
Mouse mitochondrial DNA polymerase gamma ternary complex in replication conformer
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-07-19
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
9G75
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BU of 9g75 by Molmil
Mouse mitochondrial DNA polymerase gamma ternary complex in intermediate conformer
Descriptor: DNA (primer strand), DNA (template strand), DNA polymerase subunit gamma-1, ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2024-07-19
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
9IBX
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BU of 9ibx by Molmil
Chimeric mitochondrial DNA polymerase gamma ternary complex (mAhB) in replication conformer
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2025-02-14
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
9IC3
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BU of 9ic3 by Molmil
Chimeric mitochondrial DNA polymerase gamma ternary complex (hAmB) in mouse-like error-editing conformer (composite)
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2025-02-14
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
9IBZ
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BU of 9ibz by Molmil
Chimeric mitochondrial DNA polymerase gamma ternary complex (mAhB) in human-like error-editing conformer (composite)
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2025-02-14
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
9IC1
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BU of 9ic1 by Molmil
Chimeric mitochondrial DNA polymerase gamma ternary complex (hAmB) in replication conformer
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2025-02-14
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
9IC0
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BU of 9ic0 by Molmil
Chimeric mitochondrial DNA polymerase gamma ternary complex (mAhB) in mouse-like error-editing conformer (composite)
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (primer strand), ...
Authors:Valenzuela, S, Falkenberg, M.
Deposit date:2025-02-14
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Nat Commun, 16, 2025
7OOC
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BU of 7ooc by Molmil
Mycoplasma pneumoniae 30S subunit of ribosomes in chloramphenicol-treated cells
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-05-27
Release date:2022-05-25
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7OOD
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BU of 7ood by Molmil
Mycoplasma pneumoniae 50S subunit of ribosomes in chloramphenicol-treated cells
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-05-27
Release date:2022-05-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PAK
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BU of 7pak by Molmil
70S ribosome with EF-Tu-tRNA and P-site tRNA in Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-30
Release date:2022-05-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PAI
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BU of 7pai by Molmil
70S ribosome with P-site tRNA in Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-30
Release date:2022-05-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PHA
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BU of 7pha by Molmil
70S ribosome with EF-Tu-tRNA and P-site tRNA in chloramphenicol-treated Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-08-16
Release date:2022-05-25
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7P6Z
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BU of 7p6z by Molmil
Mycoplasma pneumoniae 70S ribosome in untreated cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-18
Release date:2022-05-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PIO
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BU of 7pio by Molmil
70S ribosome with P-site tRNA in pseudouridimycin-treated Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-08-23
Release date:2022-05-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PIT
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BU of 7pit by Molmil
70S ribosome with EF-G, A/P- and P/E-site tRNAs in pseudouridimycin-treated Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-08-23
Release date:2022-05-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PAT
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BU of 7pat by Molmil
free 50S in untreated Mycoplasma pneumoniae cells
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-30
Release date:2022-05-25
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PHC
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BU of 7phc by Molmil
70S ribosome with A*- and P/E-site tRNAs in chloramphenicol-treated Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-08-16
Release date:2022-05-25
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (9.9 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PAJ
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BU of 7paj by Molmil
70S ribosome with EF-Tu-tRNA, P- and E-site tRNAs in Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-30
Release date:2022-05-25
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PAS
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BU of 7pas by Molmil
70S ribosome with P/E-site tRNA in Mycoplasma pneumoniae cells
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
Deposit date:2021-07-30
Release date:2022-05-25
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (16 Å)
Cite:Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022

 

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