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7UCL
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BU of 7ucl by Molmil
SxtA Methyltransferase variant F458H in complex with Mn2+ and malonate
Descriptor: MALONATE ION, MANGANESE (II) ION, Polyketide synthase-related protein
Authors:Lao, Y, Smith, J.L.
Deposit date:2022-03-16
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent C -Methyltransferases.
Acs Chem.Biol., 17, 2022
7UCI
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BU of 7uci by Molmil
SxtA Methyltransferase and decarboxylase didomain in complex with Mn2+ and SAH
Descriptor: GLYCEROL, MANGANESE (II) ION, Polyketide synthase-related protein, ...
Authors:Lao, Y, Skiba, M.A, Smith, J.L.
Deposit date:2022-03-16
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent C -Methyltransferases.
Acs Chem.Biol., 17, 2022
7UCH
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BU of 7uch by Molmil
AprA Methyltransferase 1 - GNAT in complex with Mn2+ , SAM, and Di-methyl-malonate
Descriptor: AprA Methyltransferase 1, GLYCEROL, MANGANESE (II) ION, ...
Authors:Skiba, M.A, Lao, Y, Smith, J.L.
Deposit date:2022-03-16
Release date:2022-06-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural Basis for Control of Methylation Extent in Polyketide Synthase Metal-Dependent C -Methyltransferases.
Acs Chem.Biol., 17, 2022
4RX0
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BU of 4rx0 by Molmil
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM265
Descriptor: 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Deng, X, Phillips, M, Tomchick, D.
Deposit date:2014-12-08
Release date:2015-07-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
Sci Transl Med, 7, 2015
5BOO
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BU of 5boo by Molmil
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM265
Descriptor: 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Phillips, M, Deng, X, Tomchick, D.
Deposit date:2015-05-27
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
Sci Transl Med, 7, 2015

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