6NTY
| 2.1 A resolution structure of the Musashi-2 (Msi2) RNA recognition motif 1 (RRM1) domain | 分子名称: | PHOSPHATE ION, RNA-binding protein Musashi homolog 2 | 著者 | Lovell, S, Kashipathy, M.M, Battaile, K.P, Lan, L, Xiaoqing, W, Cooper, A, Gao, F.P, Xu, L. | 登録日 | 2019-01-30 | 公開日 | 2019-10-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1. Proteins, 88, 2020
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6C8U
| Solution structure of Musashi2 RRM1 | 分子名称: | RNA-binding protein Musashi homolog 2 | 著者 | Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L. | 登録日 | 2018-01-25 | 公開日 | 2019-01-30 | 最終更新日 | 2022-03-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1. Proteins, 2019
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4WJA
| Crystal Structure of PAXX | 分子名称: | Uncharacterized protein C9orf142 | 著者 | Xing, M, Yang, M, Huo, W, Feng, F, Wei, L, Ning, S, Yan, Z, Li, W, Wang, Q, Hou, M, Dong, C, Guo, R, Gao, G, Ji, J, Lan, L, Liang, H, Xu, D. | 登録日 | 2014-09-29 | 公開日 | 2015-03-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat Commun, 6, 2015
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4QBA
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4GXO
| Crystal structure of Staphylococcus aureus protein SarZ mutant C13E | 分子名称: | GLYCEROL, MarR family regulatory protein | 著者 | Sun, F, Ding, Y, Ji, Q, Liang, Z, Deng, X, Wong, C.C, Yi, C, Zhang, L, Xie, S, Alvarez, S, Hicks, L.M, Luo, C, Jiang, H, Lan, L, He, C. | 登録日 | 2012-09-04 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proc.Natl.Acad.Sci.USA, 109, 2012
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4HQM
| The crystal structure of QsrR-menadione complex | 分子名称: | 2-methylnaphthalene-1,4-diol, QsrR protein | 著者 | Ji, Q, Zhang, L, Jones, M.B, Sun, F, Deng, X, Liang, H, Brugarolas, P, Gao, N, Peterson, S.N, Lan, L, Bae, T, He, C. | 登録日 | 2012-10-25 | 公開日 | 2013-03-06 | 最終更新日 | 2013-05-22 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc.Natl.Acad.Sci.USA, 110, 2013
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3STA
| Crystal structure of ClpP in tetradecameric form from Staphylococcus aureus | 分子名称: | ATP-dependent Clp protease proteolytic subunit | 著者 | Zhang, J, Ye, F, Lan, L, Jiang, H, Luo, C, Yang, C.-G. | 登録日 | 2011-07-09 | 公開日 | 2011-09-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural switching of Staphylococcus aureus Clp protease: a key to understanding protease dynamics J.Biol.Chem., 286, 2011
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3ST9
| Crystal structure of ClpP in heptameric form from Staphylococcus aureus | 分子名称: | ATP-dependent Clp protease proteolytic subunit, CALCIUM ION, GLYCEROL, ... | 著者 | Zhang, J, Ye, F, Lan, L, Jiang, H, Luo, C, Yang, C.-G. | 登録日 | 2011-07-09 | 公開日 | 2011-09-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structural switching of Staphylococcus aureus Clp protease: a key to understanding protease dynamics J.Biol.Chem., 286, 2011
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4HBL
| Crystal structure of AbfR of Staphylococcus epidermidis | 分子名称: | Transcriptional regulator, MarR family | 著者 | Liu, X, Sun, X, Gan, J, Lan, L, Yang, C.-G. | 登録日 | 2012-09-28 | 公開日 | 2013-01-02 | 最終更新日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Oxidation-sensing Regulator AbfR Regulates Oxidative Stress Responses, Bacterial Aggregation, and Biofilm Formation in Staphylococcus epidermidis. J.Biol.Chem., 288, 2013
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6JFK
| GDP bound Mitofusin2 (MFN2) | 分子名称: | CITRIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | 登録日 | 2019-02-10 | 公開日 | 2019-11-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset. Nat Commun, 10, 2019
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6JFL
| Nucleotide-free Mitofusin2 (MFN2) | 分子名称: | CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ... | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | 登録日 | 2019-02-10 | 公開日 | 2019-11-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset. Nat Commun, 10, 2019
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6JFM
| Mitofusin2 (MFN2)_T111D | 分子名称: | ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2 | 著者 | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | 登録日 | 2019-02-10 | 公開日 | 2019-11-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset. Nat Commun, 10, 2019
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6M5F
| Crystal structure of HinK, a LysR family transcriptional regulator from Pseudomonas aeruginosa | 分子名称: | Probable transcriptional regulator | 著者 | Wang, Y, Lan, L, Cao, Q, Gan, J, Wang, F. | 登録日 | 2020-03-10 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structure of HinK, a LysR family transcriptional regulator from Pseudomonas aeruginosa To Be Published
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4HQE
| The crystal structure of QsrR-DNA complex | 分子名称: | DNA (5'-D(*AP*GP*TP*AP*TP*AP*AP*TP*TP*AP*TP*TP*AP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*TP*AP*AP*TP*AP*AP*TP*TP*AP*TP*AP*CP*T)-3'), Transcriptional regulator QsrR | 著者 | He, C, Ji, Q, Zhang, L. | 登録日 | 2012-10-25 | 公開日 | 2013-03-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc.Natl.Acad.Sci.USA, 110, 2013
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4EYC
| Crystal structure of the cathelin-like domain of human cathelicidin LL-37 (hCLD) | 分子名称: | Cathelicidin antimicrobial peptide | 著者 | Pazgier, M, Pozharski, E, Toth, E, Lu, W. | 登録日 | 2012-05-01 | 公開日 | 2013-02-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37. Biochemistry, 52, 2013
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5C90
| Staphylococcus aureus ClpP mutant - Y63A | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit | 著者 | Ye, F, Liu, H, Zhang, J, Gan, J, Yang, C.-G. | 登録日 | 2015-06-26 | 公開日 | 2016-05-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Characterization of Gain-of-Function Mutant Provides New Insights into ClpP Structure Acs Chem.Biol., 11, 2016
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5DAJ
| Crystal structure of NalD, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | 分子名称: | NalD | 著者 | Chen, W.Z, Wang, D, Huang, S.Q, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | 登録日 | 2015-08-20 | 公開日 | 2016-04-20 | 最終更新日 | 2023-04-12 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa Mol.Microbiol., 100, 2016
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5XPD
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5YEW
| Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion | 分子名称: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Yan, L, Qi, Y, Huang, X, Yu, C. | 登録日 | 2017-09-20 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion Nat. Struct. Mol. Biol., 25, 2018
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6CFD
| ADEP4 bound to E. faecium ClpP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit, N-[(6aS,12S,15aS,17R,21R,23aS)-17,21-dimethyl-6,11,15,20,23-pentaoxooctadecahydro-2H,6H,11H,15H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13]oxatetraazacyclohexadecin-12-yl]-3,5-difluoro-Nalpha-[(2E)-hept-2-enoyl]-L-phenylalaninamide | 著者 | Lee, R.E, Griffith, E.C. | 登録日 | 2018-02-14 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | In VivoandIn VitroEffects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci. Antimicrob. Agents Chemother., 62, 2018
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7V6K
| Crystal structure of Sortase A from Streptococcus pyogenes in complex with ML346 | 分子名称: | 5-[3-(4-methoxyphenyl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione, MAGNESIUM ION, Sortase | 著者 | Yang, C.G, Gan, J. | 登録日 | 2021-08-20 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella. Rsc Med Chem, 13, 2022
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5HLG
| Structure of reduced AbfR bound to DNA | 分子名称: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | 著者 | Liu, G, Liu, X, Gan, J, Yang, C.G. | 登録日 | 2016-01-15 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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5HLI
| Structure of Disulfide formed AbfR | 分子名称: | CHLORIDE ION, COPPER (II) ION, MarR family transcriptional regulator | 著者 | Liu, G, Liu, X, Gan, J, Yang, C.-G. | 登録日 | 2016-01-15 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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5HLH
| Crystal structure of the overoxidized AbfR bound to DNA | 分子名称: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | 著者 | Liu, G, Liu, X, Gan, J, Yang, C.-G. | 登録日 | 2016-01-15 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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5H9T
| Crystal structure of native NalD at resolution of 2.9, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | 分子名称: | NalD | 著者 | Chen, W.Z, Wang, D, Huang, S.Q, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | 登録日 | 2015-12-29 | 公開日 | 2016-04-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa. Mol. Microbiol., 100, 2016
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