2IDH
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![BU of 2idh by Molmil](/molmil-images/mine/2idh) | |
2ING
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![BU of 2ing by Molmil](/molmil-images/mine/2ing) | X-ray Structure of the BRCA1 BRCT mutant M1775K | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | Authors: | Birrane, G, Soni, A, Ladias, J.A.A. | Deposit date: | 2006-10-07 | Release date: | 2007-09-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach. Eur.J.Hum.Genet., 16, 2008
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1I92
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![BU of 1i92 by Molmil](/molmil-images/mine/1i92) | STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION | Descriptor: | CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR | Authors: | Karthikeyan, S, Leung, T, Ladias, J.A.A. | Deposit date: | 2001-03-16 | Release date: | 2001-06-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator. J.Biol.Chem., 276, 2001
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3CMY
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![BU of 3cmy by Molmil](/molmil-images/mine/3cmy) | Structure of a homeodomain in complex with DNA | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*DAP*DCP*DAP*DTP*DAP*DAP*DP*DCP*DGP*DAP*DTP*DTP*DAP*DC)-3', 5'-D(*DTP*DGP*DTP*DAP*DAP*DTP*DCP*DGP*DAP*DTP*DTP*DAP*DTP*DG)-3', ... | Authors: | Birrane, G, Ladias, J.A.A, Soni, A. | Deposit date: | 2008-03-24 | Release date: | 2009-02-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Basis for DNA Recognition by the Human PAX3 Homeodomain. Biochemistry, 48, 2009
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2I53
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![BU of 2i53 by Molmil](/molmil-images/mine/2i53) | Crystal structure of Cyclin K | Descriptor: | ACETATE ION, Cyclin K | Authors: | Baek, K, Brown, R.S, Birrane, G, Ladias, J.A.A. | Deposit date: | 2006-08-23 | Release date: | 2007-01-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal Structure of Human Cyclin K, a Positive Regulator of Cyclin-dependent Kinase 9. J.Mol.Biol., 366, 2007
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2KG2
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![BU of 2kg2 by Molmil](/molmil-images/mine/2kg2) | Solution structure of a PDZ protein | Descriptor: | Tax1-binding protein 3 | Authors: | Durney, M.A, Birrane, G, Anklin, C, Soni, A, Ladias, J.A.A. | Deposit date: | 2009-03-02 | Release date: | 2010-01-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the human Tax-interacting protein-1. J.Biomol.Nmr, 45, 2009
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2NTE
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![BU of 2nte by Molmil](/molmil-images/mine/2nte) | Crystal Structure of the BARD1 BRCT Domains | Descriptor: | 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ... | Authors: | Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A. | Deposit date: | 2006-11-07 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the BARD1 BRCT domains. Biochemistry, 46, 2007
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2OEI
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![BU of 2oei by Molmil](/molmil-images/mine/2oei) | |
4IGK
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![BU of 4igk by Molmil](/molmil-images/mine/4igk) | |
4IFI
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![BU of 4ifi by Molmil](/molmil-images/mine/4ifi) | |
1G9O
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![BU of 1g9o by Molmil](/molmil-images/mine/1g9o) | FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR | Descriptor: | NHE-RF | Authors: | Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A. | Deposit date: | 2000-11-26 | Release date: | 2001-05-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. J.Mol.Biol., 308, 2001
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3NGH
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![BU of 3ngh by Molmil](/molmil-images/mine/3ngh) | Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1 | Descriptor: | PDZ domain-containing protein 1 | Authors: | Kocher, O, Birrane, G, Krieger, M, Ladias, J.A. | Deposit date: | 2010-06-11 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1. J.Biol.Chem., 285, 2010
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2HO2
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![BU of 2ho2 by Molmil](/molmil-images/mine/2ho2) | |
1MFG
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![BU of 1mfg by Molmil](/molmil-images/mine/1mfg) | |
1MFL
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![BU of 1mfl by Molmil](/molmil-images/mine/1mfl) | |
1GQ4
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![BU of 1gq4 by Molmil](/molmil-images/mine/1gq4) | |
1GQ5
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1QKL
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![BU of 1qkl by Molmil](/molmil-images/mine/1qkl) | hRPABC14.4, essential subunit of human RNA polymerases I, II and III | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE | Authors: | Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G. | Deposit date: | 1999-07-26 | Release date: | 1999-11-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases Nat.Struct.Biol., 6, 1999
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1Y98
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![BU of 1y98 by Molmil](/molmil-images/mine/1y98) | Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide. | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ... | Authors: | Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A. | Deposit date: | 2004-12-14 | Release date: | 2005-08-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex. Biochemistry, 44, 2005
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3BYA
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![BU of 3bya by Molmil](/molmil-images/mine/3bya) | |