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4NXX
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BU of 4nxx by Molmil
Crystal structure of the cytosolic domain of human MiD51
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Mitochondrial dynamic protein MID51
Authors:Richter, V, Kvansakul, M, Ryan, M.T.
Deposit date:2013-12-09
Release date:2013-12-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and functional analysis of MiD51, a dynamin receptor required for mitochondrial fission.
J.Cell Biol., 204, 2014
5WOU
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BU of 5wou by Molmil
Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with Guk-Holder
Descriptor: 1,2-ETHANEDIOL, GUK-holder, isoform A, ...
Authors:Caria, S, Kvansakul, M.
Deposit date:2017-08-03
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large.
J. Biol. Chem., 293, 2018
6XY4
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BU of 6xy4 by Molmil
Structural insight into sheep-pox virus mediated inhibition of apoptosis
Descriptor: Activator of apoptosis harakiri, anti-apoptotic membrane protein
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-01-29
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.04623151 Å)
Cite:Crystal structures of the sheeppox virus encoded inhibitor of apoptosis SPPV14 bound to the proapoptotic BH3 peptides Hrk and Bax.
Febs Lett., 594, 2020
6XY6
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BU of 6xy6 by Molmil
Structural insight into sheep-pox virus mediated inhibition of apoptosis
Descriptor: Apoptosis regulator BAX, anti-apoptotic membrane protein
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-01-29
Release date:2020-07-29
Method:X-RAY DIFFRACTION (2.91414642 Å)
Cite:Crystal structures of the sheeppox virus encoded inhibitor of apoptosis SPPV14 bound to the proapoptotic BH3 peptides Hrk and Bax.
Febs Lett., 594, 2020
6XA8
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BU of 6xa8 by Molmil
Crystal Structure of Human Scribble PDZ1:Vangl2 complex
Descriptor: 1,2-ETHANEDIOL, C-terminal peptide of Vangl2, PHOSPHATE ION, ...
Authors:How, J.Y, Kvansakul, M.
Deposit date:2020-06-04
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of the human Scribble-Vangl2 association in health and disease.
Biochem.J., 478, 2021
6XA6
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BU of 6xa6 by Molmil
Crystal Structure of Human Scribble PDZ3:Vangl2 Complex
Descriptor: 1,2-ETHANEDIOL, Protein scribble homolog, Vang-like protein 2
Authors:How, J.Y, Kvansakul, M.
Deposit date:2020-06-04
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of the human Scribble-Vangl2 association in health and disease.
Biochem.J., 478, 2021
6XA7
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BU of 6xa7 by Molmil
Crystal Structure of Human Scribble PDZ2:Vangl2 complex
Descriptor: 1,2-ETHANEDIOL, Protein scribble homolog, Vang-like protein 2
Authors:How, J.Y, Kvansakul, M.
Deposit date:2020-06-04
Release date:2021-03-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of the human Scribble-Vangl2 association in health and disease.
Biochem.J., 478, 2021
4AB0
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BU of 4ab0 by Molmil
X-ray crystal structure of Nicotiana alata defensin NaD1
Descriptor: FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION
Authors:Mills, G.D, Lay, F.T, Hulett, M.D, Kvansakul, M.
Deposit date:2011-12-06
Release date:2012-04-25
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.636 Å)
Cite:Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
4AAZ
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BU of 4aaz by Molmil
X-ray structure of Nicotiana alata Defensin 1 NaD1
Descriptor: 1,2-ETHANEDIOL, FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION
Authors:Lay, F.T, Mills, G.D, Hulett, M.D, Kvansakul, M.
Deposit date:2011-12-06
Release date:2012-04-25
Last modified:2012-08-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
6YLI
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BU of 6yli by Molmil
Crystal structure of human bcl-xL bound to trichoplax adhaerens trBak BH3
Descriptor: Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1, SULFATE ION
Authors:D Sa, J, Banjara, S, Kvansakul, M.
Deposit date:2020-04-07
Release date:2021-03-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis.
Sci Adv, 6, 2020
6YLD
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BU of 6yld by Molmil
Crystal structure of Trichoplax adhaerens trBcl-2L2 bound to trBak BH3
Descriptor: 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1, ...
Authors:D Sa, J, Banjara, S, Kvansakul, M.
Deposit date:2020-04-07
Release date:2021-03-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis.
Sci Adv, 6, 2020
7ADS
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BU of 7ads by Molmil
Orf virus Apoptosis inhibitor ORFV125
Descriptor: 1,2-ETHANEDIOL, Apoptosis inhibitor, CHLORIDE ION, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-09-16
Release date:2021-10-06
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.22032046 Å)
Cite:Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis.
Biochem.J., 477, 2020
7ADT
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BU of 7adt by Molmil
Orf virus Apoptosis inhibitor ORFV125
Descriptor: 1,2-ETHANEDIOL, Apoptosis inhibitor, Apoptosis regulator BAX, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2020-09-16
Release date:2021-10-06
Last modified:2022-11-23
Method:X-RAY DIFFRACTION (2.210037 Å)
Cite:Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis.
Biochem.J., 477, 2020
4CQK
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BU of 4cqk by Molmil
Crystal structure of ligand-bound NaD1
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, FLOWER-SPECIFIC DEFENSIN, SULFATE ION, ...
Authors:Lay, F.T, Mills, G.M, Poon, I.K.H, Baxter, A.A, Hulett, M.D, Kvansakul, M.
Deposit date:2014-02-17
Release date:2014-04-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Phosphoinositide-Mediated Oligomerization of a Defensin Induces Cell Lysis.
Elife, 3, 2014
7P0S
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BU of 7p0s by Molmil
ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide
Descriptor: Apoptosis inhibitor, Bcl-2-binding component 3, isoforms 1/2
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2021-06-30
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.50315881 Å)
Cite:Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk.
Viruses, 13, 2021
7P0U
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BU of 7p0u by Molmil
ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide
Descriptor: 1,2-ETHANEDIOL, Activator of apoptosis harakiri, Apoptosis inhibitor, ...
Authors:Suraweera, C.D, Hinds, M.G, Kvansakul, M.
Deposit date:2021-06-30
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.99374259 Å)
Cite:Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk.
Viruses, 13, 2021
5TZQ
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BU of 5tzq by Molmil
Crystal Structure of FPV039:Bmf BH3 complex
Descriptor: 1,2-ETHANEDIOL, Bcl-2-like protein FPV039, Bcl-2-modifying factor
Authors:Anasir, M.I, Kvansakul, M.
Deposit date:2016-11-22
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.
J. Biol. Chem., 292, 2017
5TZP
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BU of 5tzp by Molmil
Crystal structure of FPV039:Bik BH3 complex
Descriptor: 1,2-ETHANEDIOL, Bcl-2-like protein FPV039, Bik, ...
Authors:Anasir, M.I, Kvansakul, M.
Deposit date:2016-11-22
Release date:2017-05-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.
J. Biol. Chem., 292, 2017
5TWA
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BU of 5twa by Molmil
Crystal structure of Geodia cydonium BHP2 in complex with Lubomirskia baicalensis Bak-2
Descriptor: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAK-2 protein, ...
Authors:Caria, S, Hinds, M.G, Kvansakul, M.
Deposit date:2016-11-12
Release date:2017-01-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2.
Cell Death Dis, 8, 2017
5UA4
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BU of 5ua4 by Molmil
Crystal structure of A179L:Bid BH3 complex
Descriptor: 5-HL, BH3-interacting domain death agonist
Authors:Banjara, S, Caria, S, Kvansakul, M.
Deposit date:2016-12-18
Release date:2017-01-04
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insight into African Swine Fever Virus A179L-Mediated Inhibition of Apoptosis.
J. Virol., 91, 2017
5UA5
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BU of 5ua5 by Molmil
Crystal structure of A179L:Bid BH3 complex
Descriptor: 5-HL, Uncharacterized protein
Authors:Banjara, S, Caria, S, Kvansakul, M.
Deposit date:2016-12-19
Release date:2017-01-04
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insight into African Swine Fever Virus A179L-Mediated Inhibition of Apoptosis.
J. Virol., 91, 2017
5VWK
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BU of 5vwk by Molmil
Crystal structure of human Scribble PDZ1:Beta-PIX complex
Descriptor: Beta-PIX, Protein scribble homolog, SULFATE ION
Authors:Lim, K.Y.B, Kvansakul, M.
Deposit date:2017-05-22
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
5VWC
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BU of 5vwc by Molmil
Crystal structure of human Scribble PDZ1 domain
Descriptor: 1,2-ETHANEDIOL, Protein scribble homolog
Authors:Lim, K.Y.B, Kvansakul, M.
Deposit date:2017-05-21
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX.
J. Biol. Chem., 292, 2017
5VMO
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BU of 5vmo by Molmil
Crystal structure of grouper iridovirus GIV66:Bim complex
Descriptor: 1,2-ETHANEDIOL, Bak protein, Bcl-2 interacting mediator of cell death, ...
Authors:Banjara, S, Kvansakul, M.
Deposit date:2017-04-28
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
J. Biol. Chem., 293, 2018
5VMN
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BU of 5vmn by Molmil
Crystal structure of grouper iridovirus GIV66
Descriptor: 1,2-ETHANEDIOL, Bak protein, NITRATE ION
Authors:Banjara, S, Kvansakul, M.
Deposit date:2017-04-27
Release date:2018-03-07
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim.
J. Biol. Chem., 293, 2018

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