4NXX
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5WOU
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6XY4
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6XY6
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6XA8
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6XA6
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6XA7
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4AB0
| X-ray crystal structure of Nicotiana alata defensin NaD1 | Descriptor: | FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION | Authors: | Mills, G.D, Lay, F.T, Hulett, M.D, Kvansakul, M. | Deposit date: | 2011-12-06 | Release date: | 2012-04-25 | Last modified: | 2012-06-20 | Method: | X-RAY DIFFRACTION (1.636 Å) | Cite: | Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity. J.Biol.Chem., 287, 2012
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4AAZ
| X-ray structure of Nicotiana alata Defensin 1 NaD1 | Descriptor: | 1,2-ETHANEDIOL, FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION | Authors: | Lay, F.T, Mills, G.D, Hulett, M.D, Kvansakul, M. | Deposit date: | 2011-12-06 | Release date: | 2012-04-25 | Last modified: | 2012-08-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity. J.Biol.Chem., 287, 2012
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6YLI
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6YLD
| Crystal structure of Trichoplax adhaerens trBcl-2L2 bound to trBak BH3 | Descriptor: | 1,2-ETHANEDIOL, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 1, ... | Authors: | D Sa, J, Banjara, S, Kvansakul, M. | Deposit date: | 2020-04-07 | Release date: | 2021-03-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis. Sci Adv, 6, 2020
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7ADS
| Orf virus Apoptosis inhibitor ORFV125 | Descriptor: | 1,2-ETHANEDIOL, Apoptosis inhibitor, CHLORIDE ION, ... | Authors: | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | Deposit date: | 2020-09-16 | Release date: | 2021-10-06 | Last modified: | 2022-11-23 | Method: | X-RAY DIFFRACTION (2.22032046 Å) | Cite: | Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis. Biochem.J., 477, 2020
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7ADT
| Orf virus Apoptosis inhibitor ORFV125 | Descriptor: | 1,2-ETHANEDIOL, Apoptosis inhibitor, Apoptosis regulator BAX, ... | Authors: | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | Deposit date: | 2020-09-16 | Release date: | 2021-10-06 | Last modified: | 2022-11-23 | Method: | X-RAY DIFFRACTION (2.210037 Å) | Cite: | Crystal structures of ORFV125 provide insight into orf virus-mediated inhibition of apoptosis. Biochem.J., 477, 2020
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4CQK
| Crystal structure of ligand-bound NaD1 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, FLOWER-SPECIFIC DEFENSIN, SULFATE ION, ... | Authors: | Lay, F.T, Mills, G.M, Poon, I.K.H, Baxter, A.A, Hulett, M.D, Kvansakul, M. | Deposit date: | 2014-02-17 | Release date: | 2014-04-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Phosphoinositide-Mediated Oligomerization of a Defensin Induces Cell Lysis. Elife, 3, 2014
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7P0S
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7P0U
| ORF virus encoded Bcl-2 homolog ORFV125 in complex with Puma BH3 peptide | Descriptor: | 1,2-ETHANEDIOL, Activator of apoptosis harakiri, Apoptosis inhibitor, ... | Authors: | Suraweera, C.D, Hinds, M.G, Kvansakul, M. | Deposit date: | 2021-06-30 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.99374259 Å) | Cite: | Structural Investigation of Orf Virus Bcl-2 Homolog ORFV125 Interactions with BH3-Motifs from BH3-Only Proteins Puma and Hrk. Viruses, 13, 2021
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5TZQ
| Crystal Structure of FPV039:Bmf BH3 complex | Descriptor: | 1,2-ETHANEDIOL, Bcl-2-like protein FPV039, Bcl-2-modifying factor | Authors: | Anasir, M.I, Kvansakul, M. | Deposit date: | 2016-11-22 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039. J. Biol. Chem., 292, 2017
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5TZP
| Crystal structure of FPV039:Bik BH3 complex | Descriptor: | 1,2-ETHANEDIOL, Bcl-2-like protein FPV039, Bik, ... | Authors: | Anasir, M.I, Kvansakul, M. | Deposit date: | 2016-11-22 | Release date: | 2017-05-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039. J. Biol. Chem., 292, 2017
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5TWA
| Crystal structure of Geodia cydonium BHP2 in complex with Lubomirskia baicalensis Bak-2 | Descriptor: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAK-2 protein, ... | Authors: | Caria, S, Hinds, M.G, Kvansakul, M. | Deposit date: | 2016-11-12 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2. Cell Death Dis, 8, 2017
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5UA4
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5UA5
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5VWK
| Crystal structure of human Scribble PDZ1:Beta-PIX complex | Descriptor: | Beta-PIX, Protein scribble homolog, SULFATE ION | Authors: | Lim, K.Y.B, Kvansakul, M. | Deposit date: | 2017-05-22 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
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5VWC
| Crystal structure of human Scribble PDZ1 domain | Descriptor: | 1,2-ETHANEDIOL, Protein scribble homolog | Authors: | Lim, K.Y.B, Kvansakul, M. | Deposit date: | 2017-05-21 | Release date: | 2017-11-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.911 Å) | Cite: | Structural basis for the differential interaction of Scribble PDZ domains with the guanine nucleotide exchange factor beta-PIX. J. Biol. Chem., 292, 2017
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5VMO
| Crystal structure of grouper iridovirus GIV66:Bim complex | Descriptor: | 1,2-ETHANEDIOL, Bak protein, Bcl-2 interacting mediator of cell death, ... | Authors: | Banjara, S, Kvansakul, M. | Deposit date: | 2017-04-28 | Release date: | 2018-03-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim. J. Biol. Chem., 293, 2018
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5VMN
| Crystal structure of grouper iridovirus GIV66 | Descriptor: | 1,2-ETHANEDIOL, Bak protein, NITRATE ION | Authors: | Banjara, S, Kvansakul, M. | Deposit date: | 2017-04-27 | Release date: | 2018-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Grouper iridovirus GIV66 is a Bcl-2 protein that inhibits apoptosis by exclusively sequestering Bim. J. Biol. Chem., 293, 2018
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