5X5X
 
 | | Crystal structure of the Fab fragment of anti-osteocalcin C-terminal peptide antibody KTM219 | | 分子名称: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, Fd chain of anti-osteocalcin antibody KTM219, ... | | 著者 | Komatsu, M, Dong, J, Ueda, H, Arai, R. | | 登録日 | 2017-02-18 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the Fab fragment of anti-osteocalcin C-terminal peptide antibody KTM219
To be published
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4ZY3
 | | Crystal Structure of Keap1 in Complex with a small chemical compound, K67 | | 分子名称: | FORMIC ACID, Kelch-like ECH-associated protein 1, N,N'-[2-(2-oxopropyl)naphthalene-1,4-diyl]bis(4-ethoxybenzenesulfonamide) | | 著者 | Fukutomi, T, Iso, T, Suzuki, T, Takagi, K, Mizushima, T, Komatsu, M, Yamamoto, M. | | 登録日 | 2015-05-21 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
Nat Commun, 7, 2016
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2RRU
 | | Solution structure of the UBA omain of p62 and its interaction with ubiquitin | | 分子名称: | Sequestosome-1 | | 著者 | Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H. | | 登録日 | 2011-06-09 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Crystal structure of the UBA omain of p62 and its interaction with ubiquitin
To be Published
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1WXS
 | | Solution Structure of Ufm1, a ubiquitin-fold modifier | | 分子名称: | Ubiquitin-fold Modifier 1 | | 著者 | Sasakawa, H, Sakata, E, Yamaguchi, Y, Komatsu, M, Tatsumi, K, Kominami, E, Tanaka, K, Kato, K. | | 登録日 | 2005-02-01 | | 公開日 | 2006-04-18 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1
Biochem.Biophys.Res.Commun., 343, 2006
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3WDZ
 | | Crystal Structure of Keap1 in Complex with phosphorylated p62 | | 分子名称: | Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1 | | 著者 | Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M. | | 登録日 | 2013-06-26 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
Mol.Cell, 51, 2013
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3WIM
 | | GABARAP-LIR peptide complex | | 分子名称: | Gamma-aminobutyric acid receptor-associated protein, WD repeat and FYVE domain-containing protein 3 | | 著者 | Lystad, A, Ichimura, Y, Takagi, K, Yang, Y, Pankiv, S, Mizushima, T, Komatsu, M, Simonsen, A. | | 登録日 | 2013-09-19 | | 公開日 | 2014-03-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | GABARAP-LIR peptide complex
To be Published, 2014
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2D1I
 | | Structure of human Atg4b | | 分子名称: | Cysteine protease APG4B | | 著者 | Kumanomidou, T, Mizushima, T, Komatsu, M, Suzuki, A, Tanida, I, Sou, Y.S, Ueno, T, Kominami, E, Tanaka, K, Yamane, T. | | 登録日 | 2005-08-24 | | 公開日 | 2006-01-10 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of Human Atg4b, a Processing and De-conjugating Enzyme for Autophagosome-forming Modifiers
J.Mol.Biol., 355, 2006
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3B0F
 | | Crystal structure of the UBA domain of p62 and its interaction with ubiquitin | | 分子名称: | SULFATE ION, Sequestosome-1 | | 著者 | Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H. | | 登録日 | 2011-06-09 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of the ubiquitin-associated (UBA) domain of p62 and its interaction with ubiquitin.
J.Biol.Chem., 286, 2011
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2Z6P
 | | Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 | | 分子名称: | Ufm1-conjugating enzyme 1 | | 著者 | Mizushima , T, Tatsumi, K, Ozaki, Y, Kawakami, T, Suzuki, A, Ogasahara, K, Komatsu, M, Kominami, E, Tanaka, K, Yamane, T. | | 登録日 | 2007-08-06 | | 公開日 | 2007-09-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Ufc1, the Ufm1-conjugating enzyme
Biochem.Biophys.Res.Commun., 362, 2007
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2Z6O
 | | Crystal Structure of the Ufc1, Ufm1 conjugating enzyme 1 | | 分子名称: | MAGNESIUM ION, Ufm1-conjugating enzyme 1 | | 著者 | Mizushima , T, Tatsumi, K, Ozaki, Y, Kawakami, T, Suzuki, A, Ogasahara, K, Komatsu, M, Kominami, E, Tanaka, K, Yamane, T. | | 登録日 | 2007-08-06 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of Ufc1, the Ufm1-conjugating enzyme
Biochem.Biophys.Res.Commun., 362, 2007
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2ZJD
 | | Crystal Structure of LC3-p62 complex | | 分子名称: | Microtubule-associated proteins 1A/1B light chain 3B precursor, undecameric peptide from Sequestosome-1 | | 著者 | Ichimura, Y, Kumanomidou, T, Sou, Y, Mizushima, T, Ezaki, J, Ueno, T, Kominami, E, Yamane, T, Tanaka, K, Komatsu, M. | | 登録日 | 2008-03-05 | | 公開日 | 2008-06-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
J.Biol.Chem., 283, 2008
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3ADE
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7W3O
 | | Crystal structure of human CYB5R3 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3 soluble form | | 著者 | Noda, N.N. | | 登録日 | 2021-11-25 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Nat Commun, 13, 2022
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7W3N
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5HKH
 | | Crystal structure of Ufm1 in complex with UBA5 | | 分子名称: | ASP-ASN-GLU-TRP-GLY-ILE-GLU-LEU-VAL, Ubiquitin-fold modifier 1 | | 著者 | Huber, J, Doetsch, V, Rogov, V.V, Akutsu, M. | | 登録日 | 2016-01-14 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation.
J.Biol.Chem., 291, 2016
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3OQC
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7YO8
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7YO9
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6H8C
 | | Structure of the human GABARAPL2 protein in complex with the UBA5 LIR motif | | 分子名称: | Gamma-aminobutyric acid receptor-associated protein-like 2, Ubiquitin-like modifier-activating enzyme 5 | | 著者 | Huber, J, Loehr, F, Gruber, J, Akutsu, M, Guentert, P, Doetsch, V, Rogov, V.V. | | 登録日 | 2018-08-02 | | 公開日 | 2019-05-01 | | 最終更新日 | 2020-01-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5.
Autophagy, 16, 2020
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6HB9
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2MGW
 | | Solution Structure of the UBA Domain of Human NBR1 | | 分子名称: | Next to BRCA1 gene 1 protein | | 著者 | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | | 登録日 | 2013-11-09 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.
J.Biol.Chem., 289, 2014
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2MJ5
 | | Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin | | 分子名称: | Next to BRCA1 gene 1 protein, Polyubiquitin-C | | 著者 | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | | 登録日 | 2013-12-25 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.
J.Biol.Chem., 289, 2014
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2ZJ4
 | | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | | 分子名称: | 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | | 著者 | Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H. | | 登録日 | 2008-02-29 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes
Febs Lett., 583, 2009
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2ZJ3
 | | Isomerase domain of human glucose:fructose-6-phosphate amidotransferase | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | | 著者 | Nakaishi, Y, Bando, M, Kondo, K, Tsuge, H. | | 登録日 | 2008-02-29 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural analysis of human glutamine:fructose-6-phosphate amidotransferase, a key regulator in type 2 diabetes
Febs Lett., 583, 2009
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