1YFD
 
 | | Crystal structure of the Y122H mutant of ribonucleotide reductase R2 protein from E. coli | | Descriptor: | MERCURY (II) ION, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 beta chain | | Authors: | Kolberg, M, Logan, D.T, Bleifuss, G, Poetsch, S, Sjoeberg, B.M, Graeslund, A, Lubitz, W, Lassmann, G, Lendzian, F. | | Deposit date: | 2004-12-31 | | Release date: | 2005-02-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies
J.Biol.Chem., 280, 2005
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1E12
 | | Halorhodopsin, a light-driven chloride pump | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, HALORHODOPSIN, ... | | Authors: | Essen, L.-O, Kolbe, M, Oesterhelt, D. | | Deposit date: | 2000-04-14 | | Release date: | 2000-06-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of Light-Driven Chloride Pump Halorhodopsin at 1.8 A Resolution
Science, 288, 2000
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9HH5
 | | Crystal Structure of nsp15 Endoribonuclease from SARS CoV-2 in Complex with Sepantronium (YM-155) | | Descriptor: | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Nsp15 - Uridylate-specific endoribonuclease, ... | | Authors: | Chatziefthymiou, S.D, Kolbe, M, Hakanpaeae, J, Labahn, J, Windshuegel, B. | | Deposit date: | 2024-11-21 | | Release date: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Identification, validation, and characterization of approved and investigational drugs interfering with the SARS-CoV-2 endoribonuclease Nsp15.
Protein Sci., 34, 2025
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9HH6
 | | Crystal Structure of Nsp15 Endoribonuclease from SARS CoV-2 in Complex with TAS-103 | | Descriptor: | 1,2-ETHANEDIOL, 6-[2-(dimethylamino)ethylamino]-3-oxidanyl-indeno[2,1-c]quinolin-7-one, ORF1ab polyprotein, ... | | Authors: | Chatziefthymiou, S.D, Kolbe, M, Hakanpaeae, J, Labahn, J, Windshuegel, B. | | Deposit date: | 2024-11-21 | | Release date: | 2025-05-28 | | Method: | SOLUTION SCATTERING (2 Å), X-RAY DIFFRACTION | | Cite: | Identification, validation, and characterization of approved and investigational drugs interfering with the SARS-CoV-2 endoribonuclease Nsp15.
Protein Sci., 34, 2025
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6RAE
 | | Structural analysis of the Salmonella type III secretion system ATPase InvC | | Descriptor: | CHLORIDE ION, GLYCEROL, Secretory apparatus ATP synthase (Associated with virulence) | | Authors: | Bernal, I, Roemermann, J, Flacht, L, Lunelli, M, Uetrecht, C, Kolbe, M. | | Deposit date: | 2019-04-05 | | Release date: | 2019-08-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.049 Å) | | Cite: | Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC.
Protein Sci., 28, 2019
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6RAD
 | | Salmonella ATPase InvC with ADP | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | | Authors: | Bernal, I, Roemermann, J, Flacht, L, Lunelli, M, Uetrecht, C, Kolbe, M. | | Deposit date: | 2019-04-05 | | Release date: | 2019-08-21 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.796 Å) | | Cite: | Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC.
Protein Sci., 28, 2019
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6RGV
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2KV7
 | | NMR solution structure of a soluble PrgI mutant from Salmonella Typhimurium | | Descriptor: | Protein prgI | | Authors: | Schmidt, H, Poyraz, O, Seidel, K, Delissen, F, Ader, C, Tenenboim, H, Goosmann, C, Laube, B, Thuenemann, A.F, Zychlinski, A, Baldus, M, Lange, A, Griesinger, C, Kolbe, M. | | Deposit date: | 2010-03-09 | | Release date: | 2010-06-16 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Protein refolding is required for assembly of the type three secretion needle.
Nat.Struct.Mol.Biol., 17, 2010
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3ZQB
 | | PrgI-SipD from Salmonella typhimurium | | Descriptor: | GLYCEROL, PROTEIN PRGI, CELL INVASION PROTEIN SIPD | | Authors: | Lunelli, M, Kolbe, M. | | Deposit date: | 2011-06-08 | | Release date: | 2011-08-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Prgi-Sipd: Insight Into a Secretion Competent State of the Type Three Secretion System Needle Tip and its Interaction with Host Ligands
Plos Pathog., 7, 2011
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3ZQE
 | | PrgI-SipD from Salmonella typhimurium in complex with deoxycholate | | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCEROL, PROTEIN PRGI, ... | | Authors: | Lunelli, M, Kolbe, M. | | Deposit date: | 2011-06-09 | | Release date: | 2011-08-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Crystal Structure of Prgi-Sipd: Insight Into a Secretion Competent State of the Type Three Secretion System Needle Tip and its Interaction with Host Ligands
Plos Pathog., 7, 2011
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3GZ1
 | | Crystal structure of IpgC in complex with the chaperone binding region of IpaB | | Descriptor: | Chaperone protein ipgC, GLYCEROL, Invasin ipaB | | Authors: | Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M. | | Deposit date: | 2009-04-06 | | Release date: | 2009-06-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
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3GYZ
 | | Crystal structure of IpgC from Shigella flexneri | | Descriptor: | Chaperone protein ipgC, GLYCEROL, SODIUM ION, ... | | Authors: | Lunelli, M, Lokareddy, R.K, Zychlinsky, A, Kolbe, M. | | Deposit date: | 2009-04-06 | | Release date: | 2009-06-16 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | IpaB-IpgC interaction defines binding motif for type III secretion translocator
Proc.Natl.Acad.Sci.USA, 106, 2009
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3GZ2
 | | Crystal structure of IpgC in complex with an IpaB peptide | | Descriptor: | Chaperone protein ipgC, GLYCEROL, IMIDAZOLE, ... | | Authors: | Lokareddy, R.K, Lunelli, M, Kolbe, M. | | Deposit date: | 2009-04-06 | | Release date: | 2010-04-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Combination of two separate binding domains defines stoichiometry between type III secretion system chaperone IpgC and translocator protein IpaB
J.Biol.Chem., 285, 2010
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4A4Y
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6SDX
 | | Salmonella ATPase InvC with ATP gamma S | | Descriptor: | ATP synthase, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Bernal, I, Roemermann, J, Flacht, L, Lunelli, M, Uetrecht, C, Kolbe, M. | | Deposit date: | 2019-07-29 | | Release date: | 2019-08-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.645 Å) | | Cite: | Structural analysis of ligand-bound states of the Salmonella type III secretion system ATPase InvC.
Protein Sci., 28, 2019
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2X9C
 | | Crystal structure of a soluble PrgI mutant from Salmonella Typhimurium | | Descriptor: | PROTEIN PRGI | | Authors: | Poyraz, O, Schmidt, H, Seidel, K, Delissen, F, Ader, C, Tenenboim, H, Goosmann, C, Laube, B, Thuenemann, A.F, Zychlinsky, A, Baldus, M, Lange, A, Griesinger, C, Kolbe, M. | | Deposit date: | 2010-03-15 | | Release date: | 2010-06-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Protein Refolding is Required for Assembly of the Type Three Secretion Needle
Nat.Struct.Mol.Biol., 17, 2010
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2YM9
 | | SipD from Salmonella typhimurium | | Descriptor: | CELL INVASION PROTEIN SIPD, GLYCEROL, SULFATE ION | | Authors: | Lunelli, M, Kolbe, M. | | Deposit date: | 2011-06-06 | | Release date: | 2011-08-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structure of Prgi-Sipd: Insight Into a Secretion Competent State of the Type Three Secretion System Needle Tip and its Interaction with Host Ligands
Plos Pathog., 7, 2011
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2YM0
 | | Truncated SipD from Salmonella typhimurium | | Descriptor: | CELL INVASION PROTEIN SIPD, GLYCEROL | | Authors: | Lunelli, M, Kolbe, M. | | Deposit date: | 2011-06-06 | | Release date: | 2011-08-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of PrgI-SipD: insight into a secretion competent state of the type three secretion system needle tip and its interaction with host ligands.
PLoS Pathog., 7, 2011
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6ZNI
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6ZNH
 | | Structure of the Salmonella PrgI needle filament attached to the basal body | | Descriptor: | PrgI | | Authors: | Lunelli, M, Kotov, V, Wald, J, Kolbe, M, Marlovits, T.C. | | Deposit date: | 2020-07-06 | | Release date: | 2021-07-07 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Helical reconstruction of Salmonella and Shigella needle filaments attached to type 3 basal bodies.
Biochem Biophys Rep, 27, 2021
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1W69
 | | Crystal Structure of Mouse Ribonucleotide Reductase Subunit R2 under Reducing Conditions. A Fully Occupied Dinuclear Iron Cluster and Bound Acetate. | | Descriptor: | ACETIC ACID, FE (II) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN | | Authors: | Karlsen, S, Strand, K.R, Kolberg, M, Rohr, A.K, Gorbitz, C.H, Andersson, K.K. | | Deposit date: | 2004-08-16 | | Release date: | 2004-08-26 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structural Studies of Changes in the Native Dinuclear Iron Center of Ribonucleotide Reductase Protein R2 from Mouse
J.Biol.Chem., 279, 2004
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1W68
 | | Crystal Structure of Mouse Ribonucleotide Reductase Subunit R2 under Oxidizing Conditions. A Fully Occupied Dinuclear Iron Cluster. | | Descriptor: | MU-OXO-DIIRON, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 CHAIN | | Authors: | Karlsen, S, Strand, K.R, Kolberg, M, Rohr, A.K, Gorbitz, C.H, Andersson, K.K. | | Deposit date: | 2004-08-16 | | Release date: | 2004-08-26 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structural Studies of Changes in the Native Dinuclear Iron Center of Ribonucleotide Reductase Protein R2 from Mouse
J.Biol.Chem., 279, 2004
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2LPZ
 | | Atomic model of the Type-III Secretion System Needle | | Descriptor: | Protein prgI | | Authors: | Loquet, A, Sgourakis, N.G, Gupta, R, Giller, K, Riedel, D, Goosmann, C, Griesinger, C, Kolbe, M.G, Baker, D, Becker, S, Lange, A. | | Deposit date: | 2012-02-21 | | Release date: | 2012-05-16 | | Last modified: | 2024-05-15 | | Method: | SOLID-STATE NMR | | Cite: | Atomic model of the type III secretion system needle.
Nature, 486, 2012
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8AXK
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8AXL
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