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Cryo-EM structure of human insulin degrading enzyme
分子名称:	Insulin-degrading enzyme
著者	Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日	2017-10-05
公開日	2017-11-08
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (6.5 Å)
主引用文献	Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018

6B3Q

Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称:	Insulin, Insulin-degrading enzyme
著者	Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日	2017-09-22
公開日	2017-11-22
最終更新日	2021-04-28
実験手法	ELECTRON MICROSCOPY (3.7 Å)
主引用文献	Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018

6B7Z

Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
分子名称:	FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme
著者	Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日	2017-10-05
公開日	2018-01-10
最終更新日	2021-04-28
実験手法	ELECTRON MICROSCOPY (6.5 Å)
主引用文献	Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018

6BF9

Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称:	Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者	Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日	2017-10-26
公開日	2018-02-07
最終更新日	2021-04-28
実験手法	ELECTRON MICROSCOPY (7.2 Å)
主引用文献	Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018

6BF7

Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称:	Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者	Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日	2017-10-26
公開日	2018-02-07
最終更新日	2019-12-18
実験手法	ELECTRON MICROSCOPY (6.5 Å)
主引用文献	Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018

2HKD

The crystal structure of engineered OSPA
分子名称:	Outer Surface Protein A, TETRAETHYLENE GLYCOL
著者	Makabe, K, Terechko, V, Koide, S.
登録日	2006-07-03
公開日	2006-11-21
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Atomic structures of peptide self-assembly mimics. Proc.Natl.Acad.Sci.Usa, 103, 2006

3CSG

Crystal Structure of Monobody YS1(MBP-74)/Maltose Binding Protein Fusion Complex
分子名称:	Maltose-binding protein Monobody YS1 Fusion
著者	Gilbreth, R.N, Koide, S.
登録日	2008-04-09
公開日	2008-07-22
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.798 Å)
主引用文献	A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces J.Mol.Biol., 381, 2008

3CSB

Crystal Structure of Monobody YSX1/Maltose Binding Protein Fusion Complex
分子名称:	1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
著者	Gilbreth, R.N, Koide, S.
登録日	2008-04-09
公開日	2008-07-22
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.999 Å)
主引用文献	A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces J.Mol.Biol., 381, 2008

5ECJ

Crystal structure of monobody Mb(S4) bound to Prdm14 in complex with Mtgr1
分子名称:	Monobody Mb(S4), PR domain zinc finger protein 14,Protein CBFA2T2
著者	Gupta, A, Koide, S.
登録日	2015-10-20
公開日	2015-12-02
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (3.05 Å)
主引用文献	ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation. Elife, 4, 2015

7L0G

Monobody 12VC1 Bound to HRAS(G12C)
分子名称:	5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ...
著者	Teng, K.W, Hattori, T, Tsai, S, Koide, S.
登録日	2020-12-11
公開日	2021-03-24
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.54 Å)
主引用文献	Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021

7L0F

Monobody 12VC3 Bound to HRAS(WT)
分子名称:	5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GTPase HRas, MAGNESIUM ION, ...
著者	Teng, K.W, Hattori, T, Tsai, S, Koide, S.
登録日	2020-12-11
公開日	2021-03-24
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.98 Å)
主引用文献	Selective and noncovalent targeting of RAS mutants for inhibition and degradation. Nat Commun, 12, 2021

7SSU

Structure of EmrE-D3 mutant in complex with monobody L10 and methyltriphenylphosphonium
分子名称:	L10 monobody, Multidrug transporter EmrE, methyltriphenylphosphonium
著者	Kermani, A.A, Stockbridge, R.B.
登録日	2021-11-11
公開日	2022-03-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.22 Å)
主引用文献	Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. Elife, 11, 2022

7SZT

Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in low pH (protonated state)
分子名称:	Dodecyldimethylphosphine oxide, L10 monobody, Multidrug resistance protein, ...
著者	Kermani, A.A, Stockbridge, R.B, Burata, O.E.
登録日	2021-11-29
公開日	2022-03-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.32 Å)
主引用文献	Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. Elife, 11, 2022

7T00

Structure of EmrE-D3 mutant in complex with monobody L10 and benzyltrimethylammonium
分子名称:	L10 monobody, Multidrug transporter EmrE, benzyltrimethylammonium
著者	Kermani, A.A, Stockbridge, R.B.
登録日	2021-11-29
公開日	2022-03-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.91 Å)
主引用文献	Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. Elife, 11, 2022

7SVX

Structure of EmrE-D3 mutant in complex with monobody L10 and harmane
分子名称:	1-methyl-9H-pyrido[3,4-b]indole, L10 monobody, Multidrug transporter EmrE
著者	Kermani, A.A, Stockbridge, R.B.
登録日	2021-11-19
公開日	2022-03-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.9 Å)
主引用文献	Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. Elife, 11, 2022

7SV9

Structure of EmrE-D3 mutant in complex with monobody L10 and TPP
分子名称:	L10 monobody, Multidrug transporter EmrE, TETRAPHENYLPHOSPHONIUM
著者	Kermani, A.A, Stockbridge, R.B.
登録日	2021-11-18
公開日	2022-03-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.36 Å)
主引用文献	Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. Elife, 11, 2022

5CWS

Crystal structure of the intact Chaetomium thermophilum Nsp1-Nup49-Nup57 channel nucleoporin heterotrimer bound to its Nic96 nuclear pore complex attachment site
分子名称:	Nucleoporin NIC96, Nucleoporin NSP1, Nucleoporin NUP49, ...
著者	Bley, C.J, Petrovic, S, Paduch, M, Lu, V, Kossiakoff, A.A, Hoelz, A.
登録日	2015-07-28
公開日	2015-10-14
最終更新日	2019-12-25
実験手法	X-RAY DIFFRACTION (3.77 Å)
主引用文献	Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015

5CWT

Crystal structure of Chaetomium thermophilum Nup57
分子名称:	Nucleoporin NUP57
著者	Bley, C.J, Hoelz, A.
登録日	2015-07-28
公開日	2015-09-16
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015

5NKQ

Crystal structure of a dual topology fluoride ion channel.
分子名称:	FLUORIDE ION, Monobody, Putative fluoride ion transporter CrcB, ...
著者	Stockbridge, R, Miller, C, Newstead, S.
登録日	2017-03-31
公開日	2017-04-26
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.17 Å)
主引用文献	Crystal structures of a double-barrelled fluoride ion channel. Nature, 525, 2015

1X0C

Improved Crystal Structure of Isopullulanase from Aspergillus niger ATCC 9642
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Isopullulanase
著者	Mizuno, M, Tonozuka, T, Yamamura, A, Miyasaka, Y, Akeboshi, H, Kamitori, S, Nishikawa, A, Sakano, Y.
登録日	2005-03-17
公開日	2006-06-13
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Crystal Structure of Aspergillus niger Isopullulanase, a Member of Glycoside Hydrolase Family 49 J.Mol.Biol., 376, 2008

1WMR

Crystal Structure of Isopullulanase from Aspergillus niger ATCC 9642
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Isopullulanase
著者	Mizuno, M, Tonozuka, T, Miyasaka, Y, Akeboshi, H, Kamitori, S, Nishikawa, A, Sakano, Y.
登録日	2004-07-15
公開日	2005-07-19
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Crystal Structure of Aspergillus niger Isopullulanase, a Member of Glycoside Hydrolase Family 49 J.Mol.Biol., 376, 2008

7MGX

Structure of EmrE-D3 mutant in complex with monobody L10 and methyl viologen
分子名称:	1,1'-dimethyl-4,4'-bipyridin-1-ium, L10 Monobody, Multidrug transporter EmrE
著者	Kermani, A.A, Stockbridge, R.B.
登録日	2021-04-13
公開日	2022-03-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.13 Å)
主引用文献	Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. Elife, 11, 2022

7MH6

Structure of EmrE-D3 mutant in complex with monobody L10 in low pH (protonated state)
分子名称:	Monobody L10, Multidrug transporter EmrE
著者	Kermani, A.A, Stockbridge, R.B.
登録日	2021-04-14
公開日	2022-03-02
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.85 Å)
主引用文献	Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates. Elife, 11, 2022

4JQ5

Crystal structure of the human Nup49CCS2+3* coiled-coil segment
分子名称:	Nucleoporin p58/p45
著者	Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
登録日	2013-03-20
公開日	2014-09-24
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.195 Å)
主引用文献	Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015

4JNV

Crystal structure of the human Nup57CCS3* coiled-coil segment, space group C2
分子名称:	Nucleoporin p54
著者	Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
登録日	2013-03-15
公開日	2014-09-17
最終更新日	2016-02-03
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015

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