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1PXG
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BU of 1pxg by Molmil
Crystal structure of the mutated tRNA-guanine transglycosylase (TGT) D280E complexed with preQ1
Descriptor: 7-DEAZA-7-AMINOMETHYL-GUANINE, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
Authors:Kittendorf, J.D, Sgraja, T, Reuter, K, Klebe, G, Garcia, G.A.
Deposit date:2003-07-04
Release date:2003-09-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli.
J.Biol.Chem., 278, 2003
2H7X
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BU of 2h7x by Molmil
Pikromycin Thioesterase adduct with reduced triketide affinity label
Descriptor: DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ...
Authors:Giraldes, J.W, Akey, D.L, Kittendorf, J.D, Sherman, D.H, Smith, J.S, Fecik, R.A.
Deposit date:2006-06-05
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Mechanistic Insights of Polyketide Macrolactonization from Polyketide-based Affinity Labels
NAT.CHEM.BIOL., 2, 2006
2HFK
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BU of 2hfk by Molmil
Pikromycin thioesterase in complex with product 10-deoxymethynolide
Descriptor: (3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, DIMETHYL SULFOXIDE, MAGNESIUM ION, ...
Authors:Akey, D.L, Kittendorf, J.D, Giraldes, J.W, Fecik, R.A, Sherman, D.H, Smith, J.L.
Deposit date:2006-06-24
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural Basis for Macrolactonization by the Pikromycin Thioesterase
NAT.CHEM.BIOL., 2, 2006
2H7Y
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BU of 2h7y by Molmil
Pikromycin Thioesterase with covalent affinity label
Descriptor: DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ...
Authors:Giraldes, J.W, Akey, D.L, Kittendorf, J.D, Sherman, D.H, Smith, J.S, Fecik, R.A.
Deposit date:2006-06-06
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Insights of Polyketide Macrolactonization from Polyketide-based Affinity Labels
NAT.CHEM.BIOL., 2, 2006
2HFJ
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BU of 2hfj by Molmil
Pikromycin thioesterase with covalent pentaketide affinity label
Descriptor: DIMETHYL SULFOXIDE, MAGNESIUM ION, SULFATE ION, ...
Authors:Akey, D.L, Kittendorf, J.D, Giraldes, J.W, Fecik, R.A, Sherman, D.H, Smith, J.L.
Deposit date:2006-06-24
Release date:2006-09-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for Macrolactonization by the Pikromycin Thioesterase
NAT.CHEM.BIOL., 2, 2006
3LCR
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BU of 3lcr by Molmil
Thioesterase from Tautomycetin Biosynthhetic Pathway
Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, Tautomycetin biosynthetic PKS
Authors:Akey, D.L, Scaglione, J.B, Smith, J.L, Sherman, D.H.
Deposit date:2010-01-11
Release date:2010-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.
Angew.Chem.Int.Ed.Engl., 49, 2010

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