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1T84
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Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor
分子名称: (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL, Wiskott-Aldrich syndrome protein
著者Peterson, J.R, Bickford, L.C, Morgan, D, Kim, A.S, Ouerfelli, O, Kirschner, M.W, Rosen, M.K.
登録日2004-05-11
公開日2004-07-13
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nat.Struct.Mol.Biol., 11, 2004
5T0I
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BU of 5t0i by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2016-08-16
公開日2016-10-19
最終更新日2016-11-30
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0C
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BU of 5t0c by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2016-08-15
公開日2016-10-19
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0J
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BU of 5t0j by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2016-08-16
公開日2016-10-19
最終更新日2016-11-30
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0G
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BU of 5t0g by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2016-08-16
公開日2016-10-19
最終更新日2016-11-30
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0H
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BU of 5t0h by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2016-08-16
公開日2016-10-19
最終更新日2016-11-30
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VHR
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BU of 5vhr by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHN
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BU of 5vhn by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHJ
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BU of 5vhj by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHQ
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BU of 5vhq by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHO
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BU of 5vho by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHM
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BU of 5vhm by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHP
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BU of 5vhp by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHF
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BU of 5vhf by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 10, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VGZ
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BU of 5vgz by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-12
公開日2017-08-23
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHI
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BU of 5vhi by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 10, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHH
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BU of 5vhh by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 10, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5VHS
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BU of 5vhs by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
5JG6
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BU of 5jg6 by Molmil
APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C
分子名称: Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION
著者Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A.
登録日2016-04-19
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.0013 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5L9U
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BU of 5l9u by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-09-14
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5L9T
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BU of 5l9t by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-10-26
最終更新日2016-11-02
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
1DUJ
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BU of 1duj by Molmil
SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2
分子名称: SPINDLE ASSEMBLY CHECKPOINT PROTEIN
著者Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H.
登録日2000-01-17
公開日2000-03-08
最終更新日2022-12-21
実験手法SOLUTION NMR
主引用文献Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nat.Struct.Biol., 7, 2000
2QYF
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BU of 2qyf by Molmil
Crystal structure of the Mad2/p31(comet)/Mad2-binding peptide ternary complex
分子名称: MAD2L1-binding protein, Mitotic spindle assembly checkpoint protein MAD2A, peptide
著者Tomchick, D.R, Luo, X.
登録日2007-08-14
公開日2008-01-29
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献p31comet blocks Mad2 activation through structural mimicry.
Cell(Cambridge,Mass.), 131, 2007
1S2H
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BU of 1s2h by Molmil
The Mad2 spindle checkpoint protein possesses two distinct natively folded states
分子名称: Mitotic spindle assembly checkpoint protein MAD2A
著者Luo, X, Tang, Z, Xia, G, Wassmann, K, Matsumoto, T, Rizo, J, Yu, H.
登録日2004-01-08
公開日2004-03-30
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The Mad2 spindle checkpoint protein has two distinct natively folded states.
Nat.Struct.Mol.Biol., 11, 2004

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