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BINDING OF CHLOROMETHYL KETONE SUBSTRATE ANALOGUES TO CRYSTALLINE PAPAIN
分子名称:	CYSTEINE, PAPAIN
著者	Drenth, J, Kalk, K.H, Swen, H.M.
登録日	1976-11-01
公開日	1977-04-12
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Binding of chloromethyl ketone substrate analogues to crystalline papain. Biochemistry, 15, 1976

7TLN

STRUCTURAL ANALYSIS OF THE INHIBITION OF THERMOLYSIN BY AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR
分子名称:	2-(ACETYL-HYDROXY-AMINO)-4-METHYL-PENTANOIC ACID METHYL ESTER, CALCIUM ION, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A, Tronrud, D.E.
登録日	1983-01-27
公開日	1983-03-09
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor. Biochemistry, 22, 1983

5TLN

BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称:	CALCIUM ION, HONH-BENZYLMALONYL-L-ALANYLGLYCINE-P-NITROANILIDE, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A.
登録日	1982-02-08
公開日	1982-05-26
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry, 20, 1981

5TMN

Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues
分子名称:	CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ...
著者	Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues. Biochemistry, 26, 1987

3TMN

THE BINDING OF L-VALYL-L-TRYPTOPHAN TO CRYSTALLINE THERMOLYSIN ILLUSTRATES THE MODE OF INTERACTION OF A PRODUCT OF PEPTIDE HYDROLYSIS
分子名称:	CALCIUM ION, THERMOLYSIN, TRYPTOPHAN, ...
著者	Holden, H.M, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis. J.Biol.Chem., 263, 1988

4PAD

Binding of chloromethyl ketone substrate analogues to crystalline papain
分子名称:	N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide, PAPAIN
著者	Drenth, J.
登録日	1976-11-01
公開日	1977-04-12
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Binding of chloromethyl ketone substrate analogues to crystalline papain. Biochemistry, 15, 1976

6TMN

Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond
分子名称:	CALCIUM ION, N-[(2R,4S)-4-hydroxy-2-(2-methylpropyl)-4-oxido-7-oxo-9-phenyl-3,8-dioxa-6-aza-4-phosphanonan-1-oyl]-L-leucine, THERMOLYSIN, ...
著者	Tronrud, D.E, Holden, H.M, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond. Science, 235, 1987

2TMN

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称:	CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ...
著者	Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986

4TLN

BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
分子名称:	CALCIUM ION, L-LEUCYL-HYDROXYLAMINE, THERMOLYSIN, ...
著者	Matthews, B.W, Holmes, M.A.
登録日	1982-02-08
公開日	1982-05-26
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry, 20, 1981

4TMN

SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES
分子名称:	CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ...
著者	Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues. Biochemistry, 26, 1987

2OMF

OMPF PORIN
分子名称:	(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MATRIX PORIN OUTER MEMBRANE PROTEIN F
著者	Cowan, S.W.
登録日	1995-02-28
公開日	1995-12-07
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	The Refined Structure of Ompf Porin from E.Coli at 2.4 Angstroms Resolution To be Published

1TLP

CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称:	CALCIUM ION, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, THERMOLYSIN, ...
著者	Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157, 1986

1TMN

Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases
分子名称:	CALCIUM ION, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, THERMOLYSIN, ...
著者	Monzingo, A.F, Matthews, B.W.
登録日	1987-06-29
公開日	1989-01-09
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases Biochemistry, 23, 1984

1LNE

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CADMIUM ION, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNF

A structural analysis of metal substitutions in thermolysin
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者	Holland, D.R, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNB

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, FE (III) ION, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LND

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNA

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, COBALT (II) ION, DIMETHYL SULFOXIDE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1LNC

A STRUCTURAL ANALYSIS OF METAL SUBSTITUTIONS IN THERMOLYSIN
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
著者	Holland, D.R, Hausrath, A.C, Juers, D, Matthews, B.W.
登録日	1994-05-13
公開日	1995-05-08
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci., 4, 1995

1PAD

Binding of chloromethyl ketone substrate analogues to crystalline papain
分子名称:	ACETYL-ALA-ALA-PHE-ALA-CHLOROMETHYLKETONE INHIBITOR, PAPAIN
著者	Drenth, J, Kalk, K.H, Swen, H.M.
登録日	1976-11-01
公開日	1977-04-12
最終更新日	2023-09-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Binding of chloromethyl ketone substrate analogues to crystalline papain. Biochemistry, 15, 1976

3DBK

Pseudomonas aeruginosa elastase with phosphoramidon
分子名称:	CALCIUM ION, Elastase, N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN, ...
著者	McKay, D.B, Overgaard, M.T.
登録日	2008-06-01
公開日	2009-07-07
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.4 Å)
主引用文献	Structure of the Elastase of Pseudomonas aeruginosa Complexed with Phosphoramidon To be Published

1RHD

STRUCTURE OF BOVINE LIVER RHODANESE. I. STRUCTURE DETERMINATION AT 2.5 ANGSTROMS RESOLUTION AND A COMPARISON OF THE CONFORMATION AND SEQUENCE OF ITS TWO DOMAINS
分子名称:	RHODANESE
著者	Hol, W.G.J, Ploegman, J.H, Kalk, K.H, Drent, G.
登録日	1977-11-23
公開日	1978-01-16
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structure of bovine liver rhodanese. I. Structure determination at 2.5 A resolution and a comparison of the conformation and sequence of its two domains. J.Mol.Biol., 123, 1978

1THL

Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan
分子名称:	CALCIUM ION, N-({1-[(2S)-2-carboxy-4-phenylbutyl]cyclopentyl}carbonyl)-L-tryptophan, THERMOLYSIN, ...
著者	Holland, D.R, Matthews, B.W.
登録日	1993-11-17
公開日	1994-01-31
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33, 1994

1NSJ

CRYSTAL STRUCTURE OF PHOSPHORIBOSYL ANTHRANILATE ISOMERASE FROM THERMOTOGA MARITIMA
分子名称:	PHOSPHATE ION, PHOSPHORIBOSYL ANTHRANILATE ISOMERASE
著者	Hennig, M, Jansonius, J.N.J.
登録日	1996-09-13
公開日	1997-03-12
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Crystal structure at 2.0 A resolution of phosphoribosyl anthranilate isomerase from the hyperthermophile Thermotoga maritima: possible determinants of protein stability. Biochemistry, 36, 1997

1HYT

RE-DETERMINATION AND REFINEMENT OF THE COMPLEX OF BENZYLSUCCINIC ACID WITH THERMOLYSIN AND ITS RELATION TO THE COMPLEX WITH CARBOXYPEPTIDASE A
分子名称:	CALCIUM ION, DIMETHYL SULFOXIDE, L-BENZYLSUCCINIC ACID, ...
著者	Hausrath, A.C, Matthews, B.W.
登録日	1994-05-04
公開日	1994-07-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Redetermination and refinement of the complex of benzylsuccinic acid with thermolysin and its relation to the complex with carboxypeptidase A. J.Biol.Chem., 269, 1994

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