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3,4,5-Trisubstituted Isoxazoles as Novel PPARdelta Agonists: Part2
Descriptor:	(3-{4-[2-(2,4-DICHLORO-PHENOXY)-ETHYLCARBAMOYL]-5-PHENYL-ISOXAZOL-3-YL}-PHENYL)-ACETIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA
Authors:	Epple, R, Azimioara, M, Russo, R, Xie, Y, Wang, X, Cow, C, Wityak, J, Karanewsky, D, Bursulaya, B, Kreusch, A, Tuntland, T, Gerken, A, Iskandar, M, Saez, E, Seidel, H.M, Tian, S.S.
Deposit date:	2006-08-08
Release date:	2006-09-06
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	3,4,5-Trisubstituted Isoxazoles as Novel Ppardelta Agonists. Part 2 Bioorg.Med.Chem.Lett., 16, 2006

Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases
Descriptor:	N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION
Authors:	Kreusch, A, Spraggon, G.
Deposit date:	2017-06-15
Release date:	2017-10-25
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett, 8, 2017

Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases.
Descriptor:	4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine, Receptor-interacting serine/threonine-protein kinase 2
Authors:	Kreusch, A, Spraggon, G.
Deposit date:	2017-06-15
Release date:	2017-10-25
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.89 Å)
Cite:	Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett, 8, 2017