5V12
 
 | | Crystal structure of Carbon Sulfoxide lyase, Egt2 Y134F with sulfenic acid intermediate | | 分子名称: | (1S)-1-carboxy-2-[2-(hydroxysulfanyl)-1H-imidazol-4-yl]-N,N,N-trimethylethan-1-aminium, FORMIC ACID, Hercynylcysteine sulfoxide lyase | | 著者 | Irani, S, Zhang, Y. | | 登録日 | 2017-03-01 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | | 主引用文献 | Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism.
Cell Chem Biol, 25, 2018
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5V1X
 | | Carbon Sulfoxide lyase, Egt2 Y134F in complex with its substrate | | 分子名称: | (2~{S})-3-[2-[(2~{R})-2-azanyl-3-oxidanyl-3-oxidanylidene-propyl]sulfinyl-1~{H}-imidazol-4-yl]-2-(trimethyl-$l^{4}-azanyl)propanoic acid, FORMIC ACID, Hercynylcysteine sulfoxide lyase | | 著者 | Irani, S, Zhang, Y. | | 登録日 | 2017-03-02 | | 公開日 | 2018-03-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.558 Å) | | 主引用文献 | Snapshots of C-S Cleavage in Egt2 Reveals Substrate Specificity and Reaction Mechanism.
Cell Chem Biol, 25, 2018
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5UTS
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6NPW
 | | SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide | | 分子名称: | PHOSPHATE ION, Ser2/Ser5 phosphorylated peptide, Ssu72 ortholog, ... | | 著者 | Irani, S, Zhang, Y. | | 登録日 | 2019-01-18 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.486 Å) | | 主引用文献 | Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription.
J.Biol.Chem., 294, 2019
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5C2Y
 | | Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription) | | 分子名称: | GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ... | | 著者 | Yogesha, S.D, Irani, S, Zhang, Y.J. | | 登録日 | 2015-06-16 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.
Sci.Signal., 9, 2016
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6O6L
 | | The Structure of EgtB(Cabther) in complex with Hercynine | | 分子名称: | EgtB (Cabther), FE (III) ION, N,N,N-trimethyl-histidine | | 著者 | Irani, S, Zhang, Y. | | 登録日 | 2019-03-07 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity.
Acs Catalysis, 9, 2019
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6O6M
 | | The Structure of EgtB (Cabther) | | 分子名称: | EgtB (Cabther), FE (III) ION, GLYCEROL | | 著者 | Irani, S, Zhang, Y. | | 登録日 | 2019-03-07 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | | 主引用文献 | Crystal Structure of the Ergothioneine Sulfoxide Synthase fromCandidatus Chloracidobacterium thermophilumand Structure-Guided Engineering To Modulate Its Substrate Selectivity.
Acs Catalysis, 9, 2019
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6OVG
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6DU3
 | | Structure of Scp1 D96N bound to REST-pS861/4 peptide | | 分子名称: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861 | | 著者 | Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. | | 登録日 | 2018-06-19 | | 公開日 | 2018-09-26 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
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6DU2
 | | Structure of Scp1 D96N bound to REST-pS861/4 peptide | | 分子名称: | MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2 | | 著者 | Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J. | | 登録日 | 2018-06-19 | | 公開日 | 2018-09-26 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
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6NKO
 | | Crystal structure of ForH | | 分子名称: | ForH | | 著者 | Zheng, J, Irani, S, Zhang, Y. | | 登録日 | 2019-01-07 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | | 主引用文献 | Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis.
J. Am. Chem. Soc., 141, 2019
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4ZM9
 | | Crystal structure of circularly permuted human asparaginase-like protein 1 | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CITRATE ANION, ... | | 著者 | Li, W.Z, Zhang, Y. | | 登録日 | 2015-05-02 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages.
Biochemistry, 55, 2016
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