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Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (33% substrate/67% product at 72 hours)
Descriptor:	7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(CPCPCPGPAP(DZM)PAPGPTPCPCPG)-3'), ...
Authors:	Mullins, E.A, Eichman, B.F.
Deposit date:	2015-07-16
Release date:	2015-10-28
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.541 Å)
Cite:	The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527, 2015

Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog (9-mer B)
Descriptor:	AlkD, DNA (5'-D(APAPGPCPCP(DZM)PCPCPC)-3'), DNA (5'-D(TPGPGPGPTPGPGPCPT)-3')
Authors:	Mullins, E.A, Eichman, B.F.
Deposit date:	2015-07-16
Release date:	2015-10-28
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.729 Å)
Cite:	The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature, 527, 2015