1MA0
 
 | | Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with NAD+ and dodecanoic acid | | Descriptor: | Glutathione-dependent formaldehyde dehydrogenase, LAURIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Sanghani, P.C, Robinson, H, Bosron, W.F, Hurley, T.D. | | Deposit date: | 2002-07-30 | | Release date: | 2002-08-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes.
Biochemistry, 41, 2002
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1O00
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1O01
 | | Human mitochondrial aldehyde dehydrogenase complexed with crotonaldehyde, NAD(H) and Mg2+ | | Descriptor: | (2E)-BUT-2-ENAL, 1,2-ETHANEDIOL, Aldehyde dehydrogenase, ... | | Authors: | Perez-Miller, S.J, Hurley, T.D. | | Deposit date: | 2003-02-20 | | Release date: | 2003-06-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase
Biochemistry, 42, 2003
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1O04
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1NZX
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1NZZ
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1O02
 | | Human mitochondrial aldehyde dehydrogenase complexed with NADH in the presence of Mg2+ | | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Aldehyde dehydrogenase, ... | | Authors: | Perez-Miller, S.J, Hurley, T.D. | | Deposit date: | 2003-02-20 | | Release date: | 2003-06-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Coenzyme isomerization is integral to catalysis in aldehyde dehydrogenase
Biochemistry, 42, 2003
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1NZW
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1HSO
 | | HUMAN ALPHA ALCOHOL DEHYDROGENASE (ADH1A) | | Descriptor: | 4-IODOPYRAZOLE, CLASS I ALCOHOL DEHYDROGENASE 1, ALPHA SUBUNIT, ... | | Authors: | Niederhut, M.S, Gibbons, B.J, Perez-Miller, S, Hurley, T.D. | | Deposit date: | 2000-12-27 | | Release date: | 2001-01-10 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Three-dimensional structures of the three human class I alcohol dehydrogenases.
Protein Sci., 10, 2001
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1ZUM
 | | Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, Apo Form | | Descriptor: | 1,2-ETHANEDIOL, Aldehyde dehydrogenase, GUANIDINE, ... | | Authors: | Larson, H.N, Weiner, H, Hurley, T.D. | | Deposit date: | 2005-05-31 | | Release date: | 2005-06-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase "asian" variant
J.Biol.Chem., 280, 2005
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1HT0
 | | HUMAN GAMMA-2 ALCOHOL DEHYDROGENSE | | Descriptor: | CLASS I ALCOHOL DEHYDROGENASE 3, GAMMA SUBUNIT, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Niederhut, M.S, Gibbons, B.J, Perez-Miller, S, Hurley, T.D. | | Deposit date: | 2000-12-27 | | Release date: | 2001-01-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Three-dimensional structures of the three human class I alcohol dehydrogenases.
Protein Sci., 10, 2001
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1HSZ
 | | HUMAN BETA-1 ALCOHOL DEHYDROGENASE (ADH1B*1) | | Descriptor: | CLASS I ALCOHOL DEHYDROGENASE 1, BETA SUBUNIT, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Niederhut, M.S, Gibbons, B.J, Perez-Miller, S, Hurley, T.D. | | Deposit date: | 2000-12-27 | | Release date: | 2001-01-10 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Three-dimensional structures of the three human class I alcohol dehydrogenases.
Protein Sci., 10, 2001
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1LL2
 | | Crystal Structure of Rabbit Muscle Glycogenin Complexed with UDP-glucose and Manganese | | Descriptor: | GLYCOGENIN-1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE | | Authors: | Gibbons, B.J, Roach, P.J, Hurley, T.D. | | Deposit date: | 2002-04-26 | | Release date: | 2002-05-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the autocatalytic initiator of glycogen biosynthesis, glycogenin.
J.Mol.Biol., 319, 2002
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2Q95
 | | E. coli methionine aminopeptidase Mn-form with inhibitor A05 | | Descriptor: | 5-(2-CHLORO-4-NITROPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... | | Authors: | Ye, Q.-Z. | | Deposit date: | 2007-06-12 | | Release date: | 2008-01-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
Bmc Struct.Biol., 7, 2007
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2Q92
 | | E. coli methionine aminopeptidase Mn-form with inhibitor B23 | | Descriptor: | 5-(2-NITROPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... | | Authors: | Ye, Q.-Z. | | Deposit date: | 2007-06-12 | | Release date: | 2008-01-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
Bmc Struct.Biol., 7, 2007
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3D27
 | | E. coli methionine aminopeptidase with Fe inhibitor W29 | | Descriptor: | 4-(3-ethylthiophen-2-yl)benzene-1,2-diol, MANGANESE (II) ION, Methionine aminopeptidase | | Authors: | Ye, Q.Z, Chai, S, He, H.Z. | | Deposit date: | 2008-05-07 | | Release date: | 2008-08-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
J.Med.Chem., 51, 2008
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1N8K
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1N92
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8CVZ
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8CVY
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8CVX
 | | Human glycogenin-1 and glycogen synthase-1 complex in the presence of glucose-6-phosphate | | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, Glycogen [starch] synthase, muscle, ... | | Authors: | Liu, Y, Fastman, N.M, Tzitzilonis, C. | | Deposit date: | 2022-05-18 | | Release date: | 2022-07-13 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex.
Cell Rep, 40, 2022
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2Q96
 | | E. coli methionine aminopeptidase Mn-form with inhibitor A18 | | Descriptor: | 5-(2-CHLOROBENZYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... | | Authors: | Ye, Q.-Z. | | Deposit date: | 2007-06-12 | | Release date: | 2008-01-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
Bmc Struct.Biol., 7, 2007
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2Q94
 | | E. coli methionine aminopeptidase Mn-form with inhibitor A04 | | Descriptor: | 5-[2-(TRIFLUOROMETHOXY)PHENYL]-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... | | Authors: | Ye, Q.-Z. | | Deposit date: | 2007-06-12 | | Release date: | 2008-01-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
Bmc Struct.Biol., 7, 2007
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2Q93
 | | E. coli methionine aminopeptidase Mn-form with inhibitor B21 | | Descriptor: | 5-(2-METHOXYPHENYL)-2-FUROIC ACID, MANGANESE (II) ION, Methionine aminopeptidase, ... | | Authors: | Ye, Q.-Z. | | Deposit date: | 2007-06-12 | | Release date: | 2008-01-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
Bmc Struct.Biol., 7, 2007
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