5IFU
 
 | | Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with Glyburide | | Descriptor: | 1,2-ETHANEDIOL, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, CHLORIDE ION, ... | | Authors: | Dranow, D.M, Hewitt, S.N, Abendroth, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2016-02-26 | | Release date: | 2016-11-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase.
ACS Infect Dis, 3, 2017
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2KN9
 | | Solution structure of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis. Seattle Structural Genomics Center for Infectious Disease target MytuD.01635.a | | Descriptor: | Rubredoxin, ZINC ION | | Authors: | Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2009-08-20 | | Release date: | 2009-09-15 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 67, 2011
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2KOK
 | | Solution structure of an arsenate reductase (ArsC) related protein from Brucella melitensis. Seattle Structural Genomics Center for Infectious Disease target BrabA.00007.a. | | Descriptor: | arsenate reductase | | Authors: | Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W.C, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2009-09-23 | | Release date: | 2009-10-13 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis, the etiological agent responsible for brucellosis.
Acta Crystallogr.,Sect.F, 67, 2011
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4Q15
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3TL6
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3U40
 | | Crystal structure of a purine nucleoside phosphorylase from Entamoeba histolytica bound to adenosine | | Descriptor: | ADENOSINE, NITRATE ION, PHOSPHATE ION, ... | | Authors: | Edwards, T.E, Gardberg, A.S, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2011-10-06 | | Release date: | 2011-10-19 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline.
Acta Crystallogr.,Sect.F, 67, 2011
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4NCX
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3SDS
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4O2D
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6UHW
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6ALI
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6AMR
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4EMD
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4EGE
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4F3W
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4TZR
 | | Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1561 | | Descriptor: | 1-{4-amino-3-[2-(cyclopropyloxy)quinolin-6-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}-2-methylpropan-2-ol, Calmodulin-domain protein kinase 1 | | Authors: | Merritt, E.A. | | Deposit date: | 2014-07-10 | | Release date: | 2014-08-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.
J. Med. Chem., 59, 2016
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3T5S
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3TCR
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3TAV
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3TZU
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3TLF
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3TJR
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3U0B
 | | Crystal structure of an oxidoreductase from Mycobacterium smegmatis | | Descriptor: | Oxidoreductase, short chain dehydrogenase/reductase family protein, SODIUM ION | | Authors: | Arakaki, T.L, Staker, B.L, Clifton, M.C, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2011-09-28 | | Release date: | 2011-10-05 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
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3U0A
 | | Crystal structure of an Acyl-CoA thioesterase II TesB2 from Mycobacterium marinum | | Descriptor: | Acyl-CoA thioesterase II TesB2, GLYCEROL, SODIUM ION, ... | | Authors: | Arakaki, T.L, Staker, B.L, Clifton, M.C, Sankaran, B, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | Deposit date: | 2011-09-28 | | Release date: | 2011-10-05 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
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3TL3
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