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4O9H
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BU of 4o9h by Molmil
Structure of Interleukin-6 in complex with a Camelid Fab fragment
分子名称: Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7
著者Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C.
登録日2014-01-02
公開日2015-04-15
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies
To be Published
2I6S
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BU of 2i6s by Molmil
Complement component C2a
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C2a fragment, ...
著者Milder, F.J, Raaijmakers, H.C.A, Vandeputte, D.A.A, Schouten, A, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
登録日2006-08-29
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2I6Q
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Complement component C2a
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C2a fragment, ...
著者Milder, F.J, Raaijmakers, H.C.A, Vandeputte, D.A.A, Schouten, A, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
登録日2006-08-29
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2OK5
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BU of 2ok5 by Molmil
Human Complement factor B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement factor B, ...
著者Milder, F.J, Gomes, L, Schouten, A, Janssen, B.J.C, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
登録日2007-01-16
公開日2007-02-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Factor B structure provides insights into activation of the central protease of the complement system.
Nat.Struct.Mol.Biol., 14, 2007
2WFH
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BU of 2wfh by Molmil
The Human Slit 2 Dimerization Domain D4
分子名称: SLIT HOMOLOG 2 PROTEIN C-PRODUCT, SULFATE ION
著者Seiradake, E, von Philipsborn, A.C, Henry, M, Fritz, M, Lortat-Jacob, H, Jamin, M, Hemrika, W, Bastmeyer, M, Cusack, S, McCarthy, A.A.
登録日2009-04-06
公開日2009-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and functional relevance of the Slit2 homodimerization domain.
EMBO Rep., 10, 2009
2V9T
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BU of 2v9t by Molmil
Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1
分子名称: ROUNDABOUT HOMOLOG 1, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
著者Morlot, C, Cusack, S, McCarthy, A.A.
登録日2007-08-25
公開日2007-09-25
最終更新日2012-08-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9R
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BU of 2v9r by Molmil
First and second Ig domains from human Robo1 (Form 2)
分子名称: ROUNDABOUT HOMOLOG 1, SULFATE ION
著者Morlot, C, Cusack, S, McCarthy, A.A.
登録日2007-08-25
公開日2007-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9Q
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First and second Ig domains from human Robo1
分子名称: MERCURY (II) ION, ROUNDABOUT HOMOLOG 1
著者Morlot, C, Cusack, S, McCarthy, A.A.
登録日2007-08-25
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
2V9S
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BU of 2v9s by Molmil
Second LRR domain of human Slit2
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
著者Morlot, C, Cusack, S, McCarthy, A.A.
登録日2007-08-25
公開日2007-09-25
最終更新日2014-11-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
3D68
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BU of 3d68 by Molmil
Crystal structure of a T325I/T329I/H333Y/H335Q mutant of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI-IIYQ)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, Carboxypeptidase B2, ...
著者Brondijk, T.H.C, Huizinga, E.G.
登録日2008-05-19
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D66
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BU of 3d66 by Molmil
Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ZINC ION
著者Brondijk, T.H.C, Huizinga, E.G.
登録日2008-05-19
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
3D67
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Crystal structure of Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) in complex with 2-guanidino-ethyl-mercaptosuccinic acid (GEMSA)
分子名称: (2-GUANIDINOETHYLMERCAPTO)SUCCINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase B2, ...
著者Brondijk, T.H.C, Huizinga, E.G.
登録日2008-05-19
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood, 112, 2008
2V70
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BU of 2v70 by Molmil
Third LRR domain of human Slit2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SLIT HOMOLOG 2 PROTEIN N-PRODUCT
著者Morlot, C, Cusack, S, McCarthy, A.A.
登録日2007-07-24
公開日2007-08-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Production of Slit2 Lrr Domains in Mammalian Cells for Structural Studies and the Structure of Human Slit2 Domain 3.
Acta Crystallogr.,Sect.D, 63, 2007
1VNE
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BU of 1vne by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT D292A
分子名称: VANADATE ION, VANADIUM CHLOROPEROXIDASE
著者Macedo-Ribeiro, S, Messerschmidt, A.
登録日1999-01-20
公開日1999-08-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNF
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BU of 1vnf by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT R360A
分子名称: VANADATE ION, VANADIUM CHLOROPEROXIDASE
著者Macedo-Ribeiro, S, Messerschmidt, A.
登録日1999-01-20
公開日1999-08-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNG
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CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT H404A
分子名称: VANADATE ION, VANADIUM CHLOROPEROXIDASE
著者Macedo-Ribeiro, S, Messerschmidt, A.
登録日1999-01-20
公開日1999-08-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNH
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BU of 1vnh by Molmil
CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: MUTANT H496A
分子名称: VANADATE ION, VANADIUM CHLOROPEROXIDASE
著者Macedo-Ribeiro, S, Messerschmidt, A.
登録日1999-01-20
公開日1999-08-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNI
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CHLOROPEROXIDASE FROM THE FUNGUS CURVULARIA INAEQUALIS: RECOMBINANT HOLO-CHLOROPEROXIDASE
分子名称: VANADATE ION, VANADIUM CHLOROPEROXIDASE
著者Macedo-Ribeiro, S, Messerschmidt, A.
登録日1999-01-20
公開日1999-08-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
1VNS
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RECOMBINANT APO-CHLOROPEROXIDASE FROM CURVULARIA INAEQUALIS
分子名称: SULFATE ION, VANADIUM CHLOROPEROXIDASE
著者Macedo-Ribeiro, S, Messerschmidt, A.
登録日1999-01-14
公開日1999-08-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献X-ray crystal structures of active site mutants of the vanadium-containing chloroperoxidase from the fungus Curvularia inaequalis.
J.Biol.Inorg.Chem., 4, 1999
3BB0
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Crystal Structure of a Trapped Phosphate-Intermediate in Vanadium Apochloroperoxidase Catalyzing a Dephosphorylation Reaction
分子名称: PHOSPHITE ION, SULFATE ION, Vanadium chloroperoxidase
著者Messerschmidt, A, Macedo-Ribeiro, S.
登録日2007-11-09
公開日2008-02-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a trapped phosphate intermediate in vanadium apochloroperoxidase catalyzing a dephosphorylation reaction
Biochemistry, 47, 2008

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