5JFT
 
 | | Zebra Fish Caspase-3 | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACE-ASP-GLU-VAL-ASK, ... | | Authors: | Tucker, M.B, MacKenzie, S.H, Maciag, J.J, Dirscherl, H, Swartz, P.D, Yoder, J.A, Hamilton, P.T, Clark, A.C. | | Deposit date: | 2016-04-19 | | Release date: | 2016-10-26 | | Last modified: | 2016-11-02 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish.
Protein Sci., 25, 2016
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6PPM
 | | Ancestral Caspase 6 | | Descriptor: | Ancestral Caspase-6 Large Subunit, Ancestral Caspase-6 small subunit, VAL-GLU-ILE-ASP Inhibitor | | Authors: | Clark, A.C. | | Deposit date: | 2019-07-08 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity.
Biochem.J., 476, 2019
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6PDQ
 | | Ancestral Effector Caspase 3/6/7 | | Descriptor: | Ac-DEVD inhibitor, Ancestral Effector Caspase-3/6/7 | | Authors: | Clark, A.C. | | Deposit date: | 2019-06-19 | | Release date: | 2019-11-13 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity.
Biochem.J., 476, 2019
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7JL7
 | | Zebrafish Caspase N213T | | Descriptor: | ASP-GLU-VAL-ASP peptide, Caspase 3, apoptosis-related cysteine protease a | | Authors: | Clark, A.C, Swartz, P.D. | | Deposit date: | 2020-07-29 | | Release date: | 2021-01-27 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Remodeling hydrogen bond interactions results in relaxed specificity of Caspase-3.
Biosci.Rep., 41, 2021
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6WI4
 | | Caspases from Scleractinian Coral | | Descriptor: | ACE-DEVD inhibitor, Caspase-3 | | Authors: | Clark, A.C, Swartz, P.D. | | Deposit date: | 2020-04-08 | | Release date: | 2020-08-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Caspases from scleractinian coral show unique regulatory features.
J.Biol.Chem., 295, 2020
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4Z81
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4Z80
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