6PDQ
Ancestral Effector Caspase 3/6/7
Summary for 6PDQ
Entry DOI | 10.2210/pdb6pdq/pdb |
Descriptor | Ancestral Effector Caspase-3/6/7, Ac-DEVD inhibitor, ... (4 entities in total) |
Functional Keywords | ancestral effector caspase, protease, ancestral protein reconstruction, apoptosis |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 54269.16 |
Authors | Clark, A.C. (deposition date: 2019-06-19, release date: 2019-11-13, Last modification date: 2020-01-01) |
Primary citation | Grinshpon, R.D.,Shrestha, S.,Titus-McQuillan, J.,Hamilton, P.T.,Swartz, P.D.,Clark, A.C. Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity. Biochem.J., 476:3475-3492, 2019 Cited by PubMed: 31675069DOI: 10.1042/BCJ20190625 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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