7A8P
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![BU of 7a8p by Molmil](/molmil-images/mine/7a8p) | Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor. | Descriptor: | (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid, DNA-directed RNA polymerase, mitochondrial | Authors: | Hillen, H.S, Bonekamp, N, Peter, B, Felser, A, Bergbrede, T, Choidas, A, Horn, M, Unger, A, di Lucrezia, R, Atanassov, I, Li, X, Koch, U, Menninger, S, Boros, J, Habenberger, P, Giavalisco, P, Cramer, P, Denzel, M, Nussbaumer, P, Klebl, B, Falkenberg, M, Gustafsson, C.M, Larsson, N.G. | Deposit date: | 2020-08-30 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Small-molecule inhibitors of human mitochondrial DNA transcription. Nature, 588, 2020
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6RCI
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![BU of 6rci by Molmil](/molmil-images/mine/6rci) | Crystal structure of REXO2 | Descriptor: | Oligoribonuclease, mitochondrial | Authors: | Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. | Deposit date: | 2019-04-11 | Release date: | 2019-10-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol.Cell, 76, 2019
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6RCN
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![BU of 6rcn by Molmil](/molmil-images/mine/6rcn) | Crystal structure of REXO2-D199A-dAdA | Descriptor: | DNA (5'-D(P*AP*A)-3'), MAGNESIUM ION, Oligoribonuclease, ... | Authors: | Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. | Deposit date: | 2019-04-11 | Release date: | 2019-10-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol.Cell, 76, 2019
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6RCL
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![BU of 6rcl by Molmil](/molmil-images/mine/6rcl) | Crystal structure of REXO2-D199A-AA | Descriptor: | MAGNESIUM ION, Oligoribonuclease, mitochondrial, ... | Authors: | Spahr, H, Nicholls, T.J, Larsson, N.G, Gustafsson, C.M. | Deposit date: | 2019-04-11 | Release date: | 2019-10-09 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria. Mol.Cell, 76, 2019
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3M66
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![BU of 3m66 by Molmil](/molmil-images/mine/3m66) | Crystal structure of human Mitochondrial Transcription Termination Factor 3 | Descriptor: | mTERF domain-containing protein 1, mitochondrial | Authors: | Spahr, H, Samuelsson, T, Hallberg, B.M, Gustafsson, C.M. | Deposit date: | 2010-03-15 | Release date: | 2010-05-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain. Biochem.Biophys.Res.Commun., 397, 2010
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7ZC4
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![BU of 7zc4 by Molmil](/molmil-images/mine/7zc4) | Cryo-EM structure of POLRMT mutant. | Descriptor: | DNA-directed RNA polymerase, mitochondrial | Authors: | Das, H, Hallberg, B.M. | Deposit date: | 2022-03-25 | Release date: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022
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7PZR
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![BU of 7pzr by Molmil](/molmil-images/mine/7pzr) | Cryo-EM structure of POLRMT in free form. | Descriptor: | DNA-directed RNA polymerase, mitochondrial | Authors: | Das, H, Hallberg, B.M. | Deposit date: | 2021-10-13 | Release date: | 2022-11-16 | Last modified: | 2023-05-31 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization. Cell, 185, 2022
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7PZP
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![BU of 7pzp by Molmil](/molmil-images/mine/7pzp) | |
4FP9
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![BU of 4fp9 by Molmil](/molmil-images/mine/4fp9) | Human MTERF4-NSUN4 protein complex | Descriptor: | S-ADENOSYLMETHIONINE, SULFATE ION, mTERF domain-containing protein 2, ... | Authors: | Spahr, H, Hallberg, B.M. | Deposit date: | 2012-06-21 | Release date: | 2012-09-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis. Proc.Natl.Acad.Sci.USA, 109, 2012
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