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4HJ0
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BU of 4hj0 by Molmil
Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution
分子名称: Gastric inhibitory polypeptide receptor, Gipg013 Fab, Antagonizing antibody to the GIP Receptor, ...
著者Madhurantakam, C, Ravn, P, Gruetter, M.G, Jackson, R.H.
登録日2012-10-12
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor.
J.Biol.Chem., 288, 2013
4JB8
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BU of 4jb8 by Molmil
Caspase-7 in Complex with DARPin C7_16
分子名称: Caspase-7 subunit p11, Caspase-7 subunit p20, DARPin C7_16
著者Fluetsch, A, Seeger, M.A, Gruetter, M.G.
登録日2013-02-19
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity.
Protein Sci., 22, 2013
4J7W
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BU of 4j7w by Molmil
E3_5 DARPin L86A mutant
分子名称: DARPin_E3_5_L86A
著者Seeger, M.A, Gruetter, M.G.
登録日2013-02-14
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity.
Protein Sci., 22, 2013
4J8Y
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BU of 4j8y by Molmil
E3_5 DARPin D77S mutant
分子名称: DARPin_E3_5_D77S
著者Seeger, M.A, Gruetter, M.G.
登録日2013-02-15
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity.
Protein Sci., 22, 2013
3QF4
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BU of 3qf4 by Molmil
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ...
著者Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A.
登録日2011-01-21
公開日2012-03-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Nat.Struct.Mol.Biol., 19, 2012
4LSZ
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BU of 4lsz by Molmil
Caspase-7 in Complex with DARPin D7.18
分子名称: Caspase-7 subunit p10, Caspase-7 subunit p20, DARPin D7.18
著者Fluetsch, A, Lukarska, M, Gruetter, M.G.
登録日2013-07-23
公開日2014-07-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise.
Biochem.J., 461, 2014
2MIB
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BU of 2mib by Molmil
THE STRUCTURE OF MURINE INTERLEUKIN-1 BETA AT 2.8 ANGSTROMS RESOLUTION
分子名称: INTERLEUKIN-1 BETA
著者Priestle, J.P, Van Oostrum, J, Schmitz, A, Gruetter, M.G.
登録日1993-12-06
公開日1994-01-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献The structure of murine interleukin-1 beta at 2.8 A resolution.
J.Struct.Biol., 107, 1991
2K7Z
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BU of 2k7z by Molmil
Solution Structure of the Catalytic Domain of Procaspase-8
分子名称: Caspase-8
著者Keller, N, Zerbe, O, Mares, J, Gruetter, M.G.
登録日2008-08-28
公開日2009-03-24
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation.
Structure, 17, 2009
2P2C
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BU of 2p2c by Molmil
Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin)
分子名称: Caspase-2
著者Roschitzki Voser, H, Briand, C, Capitani, G, Gruetter, M.G.
登録日2007-03-07
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.
Structure, 15, 2007
4I2O
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BU of 4i2o by Molmil
The Structure of FixK2 from Bradyrhizobium japonicum
分子名称: FixK2 protein, Promoter of fixK2 direct target, fixN, ...
著者Bonnet, M, Kurz, M, Mesa, S, Briand, C, Hennecke, H, Gruetter, M.G.
登録日2012-11-22
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The Structure of Bradyrhizobium japonicum Transcription Factor FixK2 Unveils Sites of DNA Binding and Oxidation.
J.Biol.Chem., 288, 2013
4Q4A
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BU of 4q4a by Molmil
Improved model of AMP-PNP bound TM287/288
分子名称: ABC transporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-14
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q4H
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BU of 4q4h by Molmil
TM287/288 in its apo state
分子名称: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-14
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.527 Å)
主引用文献Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q7M
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BU of 4q7m by Molmil
Structure of NBD288-Avi of TM287/288
分子名称: Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-25
公開日2015-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
4Q4J
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BU of 4q4j by Molmil
Structure of crosslinked TM287/288_S498C_S520C mutant
分子名称: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A.
登録日2014-04-14
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q7K
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BU of 4q7k by Molmil
Structure of NBD287 of TM287/288
分子名称: ABC transporter
著者Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-25
公開日2015-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
4Q7L
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BU of 4q7l by Molmil
Structure of NBD288 of TM287/288
分子名称: NICKEL (II) ION, Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-25
公開日2015-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
1PII
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BU of 1pii by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION
分子名称: N-(5'PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE, PHOSPHATE ION
著者Wilmanns, M, Priestle, J.P, Jansonius, J.N.
登録日1991-06-21
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of the bifunctional enzyme phosphoribosylanthranilate isomerase: indoleglycerolphosphate synthase from Escherichia coli refined at 2.0 A resolution.
J.Mol.Biol., 223, 1992
1TFG
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BU of 1tfg by Molmil
AN UNUSUAL FEATURE REVEALED BY THE CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF HUMAN TRANSFORMING GROWTH FACTOR-BETA2
分子名称: TRANSFORMING GROWTH FACTOR, BETA 2
著者Gruetter, M, Schlunegger, M.
登録日1992-11-17
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2.
Nature, 358, 1992
1L34
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BU of 1l34 by Molmil
HIGH-RESOLUTION STRUCTURE OF THE TEMPERATURE-SENSITIVE MUTANT OF PHAGE LYSOZYME, ARG 96 (RIGHT ARROW) HIS
分子名称: T4 LYSOZYME
著者Weaver, L.H, Matthews, B.W.
登録日1989-05-01
公開日1990-01-15
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution structure of the temperature-sensitive mutant of phage lysozyme, Arg 96----His.
Biochemistry, 28, 1989
1L26
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BU of 1l26 by Molmil
REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY
分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者Bell, J.A, Dao-Pin, S, Matthews, B.W.
登録日1989-05-01
公開日1990-01-15
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability.
Science, 239, 1988
1L44
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BU of 1l44 by Molmil
CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称: T4 LYSOZYME
著者Daopin, S, Matthews, B.W.
登録日1991-01-28
公開日1991-10-15
最終更新日2022-11-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability.
J.Mol.Biol., 221, 1991
1L58
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BU of 1l58 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者Nicholson, H, Matthews, B.W.
登録日1991-05-06
公開日1991-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献
To be Published
1L64
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BU of 1l64 by Molmil
TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者Heinz, D, Matthews, B.W.
登録日1991-09-23
公開日1991-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence.
Proc.Natl.Acad.Sci.USA, 89, 1992
1L71
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MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者Zhang, X, Matthews, B.W.
登録日1991-09-23
公開日1991-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein Sci., 1, 1992
1L76
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TOLERANCE OF T4 LYSOZYME TO PROLINE SUBSTITUTIONS WITHIN THE LONG INTERDOMAIN ALPHA-HELIX ILLUSTRATES THE ADAPTABILITY OF PROTEINS TO POTENTIALLY DESTABILIZING LESIONS
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者Sauer, U, Matthews, B.W.
登録日1991-09-23
公開日1991-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tolerance of T4 lysozyme to proline substitutions within the long interdomain alpha-helix illustrates the adaptability of proteins to potentially destabilizing lesions.
J.Biol.Chem., 267, 1992

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