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1MXX
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BU of 1mxx by Molmil
crystal titration experiments (AMPA co-crystals soaked in 100 uM BrW)
Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY3
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BU of 1my3 by Molmil
crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form
Descriptor: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY0
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BU of 1my0 by Molmil
crystal titration experiments (AMPA co-crystals soaked in 100 nM BrW)
Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXV
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BU of 1mxv by Molmil
crystal titration experiments (AMPA co-crystals soaked in 10 mM BrW)
Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXU
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BU of 1mxu by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments)
Descriptor: 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MY2
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BU of 1my2 by Molmil
crystal titration experiment (AMPA complex control)
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MXY
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BU of 1mxy by Molmil
crystal titration experiments (AMPA co-crystals soaked in 10 uM BrW)
Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MXW
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BU of 1mxw by Molmil
crystal titration experiments (AMPA co-crystals soaked in 1 mM BrW)
Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MY4
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BU of 1my4 by Molmil
crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form
Descriptor: 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1MXZ
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BU of 1mxz by Molmil
crystal titration experiments (AMPA co-crystals soaked in 1 uM BrW)
Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal.
Biochemistry, 42, 2003
1MY1
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BU of 1my1 by Molmil
crystal titration experiments (AMPA co-crystals soaked in 10 nM BrW)
Descriptor: GLUTAMATE RECEPTOR 2, ZINC ION
Authors:Jin, R, Gouaux, E.
Deposit date:2002-10-03
Release date:2003-06-10
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal
Biochemistry, 42, 2003
1P1N
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BU of 1p1n by Molmil
GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-13
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1PB7
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BU of 1pb7 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION
Descriptor: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB8
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BU of 1pb8 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION
Descriptor: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB9
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BU of 1pb9 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION
Descriptor: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-06-24
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PBQ
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BU of 1pbq by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION
Descriptor: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1
Authors:Furukawa, H, Gouaux, E.
Deposit date:2003-05-14
Release date:2003-07-29
Last modified:2020-07-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1LB8
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BU of 1lb8 by Molmil
Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with AMPA at 2.3 resolution
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LB9
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BU of 1lb9 by Molmil
Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with antagonist DNQX at 2.3 A resolution
Descriptor: 6,7-DINITROQUINOXALINE-2,3-DIONE, Glutamate receptor 2, SULFATE ION
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LBB
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BU of 1lbb by Molmil
Crystal structure of the GluR2 ligand binding domain mutant (S1S2J-N754D) in complex with kainate at 2.1 A resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamine receptor 2
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LBC
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BU of 1lbc by Molmil
Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamine Receptor 2, ...
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-05-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1P1W
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BU of 1p1w by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2 precursor, SULFATE ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-14
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1Q
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BU of 1p1q by Molmil
Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with AMPA
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, ZINC ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-13
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1U
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BU of 1p1u by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form)
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-14
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1O
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BU of 1p1o by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) mutant L650T in complex with quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-13
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
2LKF
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BU of 2lkf by Molmil
LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS
Descriptor: LEUKOCIDIN F SUBUNIT
Authors:Olson, R, Nariya, H, Yokota, K, Kamio, Y, Gouaux, J.E.
Deposit date:1998-07-28
Release date:1999-07-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel.
Nat.Struct.Biol., 6, 1999

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數據於2024-05-15公開中

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