3F3C
 
 | | Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium | | Descriptor: | 4-FLUORO-L-PHENYLALANINE, SODIUM ION, Transporter, ... | | Authors: | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | | Deposit date: | 2008-10-30 | | Release date: | 2008-12-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A competitive inhibitor traps LeuT in an open-to-out conformation.
Science, 322, 2008
|
|
3GIA
 | | Crystal Structure of ApcT Transporter | | Descriptor: | BICINE, DECANE, Uncharacterized protein MJ0609 | | Authors: | Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2009-03-05 | | Release date: | 2009-08-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
|
|
3GI9
 | | Crystal Structure of ApcT Transporter Bound to 7F11 Monoclonal Fab Fragment | | Descriptor: | 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609 | | Authors: | Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2009-03-05 | | Release date: | 2009-08-18 | | Last modified: | 2017-06-07 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
|
|
3GI8
 | | Crystal Structure of ApcT K158A Transporter Bound to 7F11 Monoclonal Fab Fragment | | Descriptor: | 7F11 Anti-ApcT Monoclonal Fab Heavy Chain, 7F11 Anti-ApcT Monoclonal Fab Light Chain, Uncharacterized protein MJ0609 | | Authors: | Shaffer, P.L, Goehring, A.S, Shankaranarayanan, A, Gouaux, E, New York Consortium on Membrane Protein Structure (NYCOMPS) | | Deposit date: | 2009-03-05 | | Release date: | 2009-08-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structure and mechanism of a na+-independent amino Acid transporter.
Science, 325, 2009
|
|
3H5W
 | | Crystal structure of the GluR2-ATD in space group P212121 without solvent | | Descriptor: | Glutamate receptor 2 | | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | Deposit date: | 2009-04-22 | | Release date: | 2009-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.686 Å) | | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
|
|
3H5V
 | | Crystal structure of the GluR2-ATD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | | Deposit date: | 2009-04-22 | | Release date: | 2009-06-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain.
Embo J., 28, 2009
|
|
3H9V
 | | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.1 Angstroms | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GADOLINIUM ATOM, P2X purinoceptor | | Authors: | Kawate, T, Michel, J.C, Gouaux, E. | | Deposit date: | 2009-04-30 | | Release date: | 2009-07-28 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
|
|
3I5D
 | | Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor | | Authors: | Kawate, T, Michel, J.C, Gouaux, E. | | Deposit date: | 2009-07-05 | | Release date: | 2009-08-04 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (3.46 Å) | | Cite: | Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
|
|
3IJ4
 | |
4NYK
 | | Structure of a membrane protein | | Descriptor: | Acid-sensing ion channel 1, CHLORIDE ION | | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | | Deposit date: | 2013-12-10 | | Release date: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Pore architecture and ion sites in acid-sensing ion channels and P2X receptors.
Nature, 460, 2009
|
|
4U2P
 | |
4U1X
 | | Full length GluA2-kainate-(R,R)-2b complex crystal form B | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, ... | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-16 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.301 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U1W
 | | Full length GluA2-kainate-(R,R)-2b complex crystal form A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, ... | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-16 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U2Q
 | | Full-length AMPA subtype ionotropic glutamate receptor GluA2 in complex with partial agonist kainate | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 | | Authors: | Duerr, K.L, Chen, L, Gouaux, E. | | Deposit date: | 2014-07-17 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.5247 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U2R
 | | Crystal structure of the GLUR2 ligand binding core (S1S2J, flip variant) in the apo state | | Descriptor: | Glutamate receptor 2, SULFATE ION | | Authors: | Duerr, K.L, Chen, L, Gouaux, E. | | Deposit date: | 2014-07-17 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.4114 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U1Z
 | | GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form D | | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-16 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9401 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U21
 | | GluA2flip sLBD complexed with FW and (R,R)-2b crystal form E | | Descriptor: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-16 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.3908 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U22
 | | GluA2flip sLBD complexed with FW and (R,R)-2b crystal form D | | Descriptor: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-16 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.4409 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U23
 | | GluA2flip sLBD complexed with FW and (R,R)-2b crystal form F | | Descriptor: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2,Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-16 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6734 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U5D
 | | Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Con-ikot-ikot, ... | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-25 | | Release date: | 2014-08-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.5757 Å) | | Cite: | X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
|
|
4U5G
 | | Crystal structure of con-ikot-ikot toxin | | Descriptor: | Con-ikot-ikot, ZINC ION | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-25 | | Release date: | 2014-08-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1997 Å) | | Cite: | X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
|
|
4U5H
 | | crystal structure of con-ikot-ikot toxin | | Descriptor: | Con-ikot-ikot | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-25 | | Release date: | 2014-08-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
|
|
4U1Y
 | | Full length GluA2-FW-(R,R)-2b complex | | Descriptor: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2, ... | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-16 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.8999 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U1O
 | | GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form C | | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-15 | | Release date: | 2014-08-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8501 Å) | | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States.
Cell, 158, 2014
|
|
4U5C
 | | Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist FW and postitive modulator (R,R)-2b complex | | Descriptor: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Con-ikot-ikot, ... | | Authors: | Chen, L, Gouaux, E. | | Deposit date: | 2014-07-25 | | Release date: | 2014-08-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.6883 Å) | | Cite: | X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345, 2014
|
|
