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6XWM
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BU of 6xwm by Molmil
Mechanism of substrate release in neurotransmitter:sodium symporters: the structure of LeuT in an inward-facing occluded conformation
Descriptor: Na(+):neurotransmitter symporter (Snf family), PHENYLALANINE, SODIUM ION
Authors:Boesen, T, Nissen, P, Gotfryd, K, Loland, C.J, Gether, U.
Deposit date:2020-01-24
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release.
Nat Commun, 11, 2020
2LUI
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BU of 2lui by Molmil
Structure of the PICK PDZ domain in complex with the DAT C-terminal
Descriptor: PICK1 PDZ DOMAIN FUSED TO THE C10 DAT LIGAND
Authors:Erlendsson, S, Rathje, M, Heidarsson, P.O, Poulsen, F.M, Madsen, K.L, Teilum, K, Gether, U.
Deposit date:2012-06-14
Release date:2013-06-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/discs-large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands.
J.Biol.Chem., 289, 2014
7ZH0
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BU of 7zh0 by Molmil
Structure of human OCT3 in lipid nanodisc
Descriptor: Solute carrier family 22 member 3
Authors:Khanppnavar, B, Korkhov, V, Qi, C.
Deposit date:2022-04-05
Release date:2022-11-09
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7ZH6
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BU of 7zh6 by Molmil
Structure of human OCT3 in complex with inhibitor Corticosterone
Descriptor: CORTICOSTERONE, Solute carrier family 22 member 3
Authors:Khanppnavar, B, Korkhov, V.
Deposit date:2022-04-05
Release date:2022-11-09
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022
7ZHA
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BU of 7zha by Molmil
Structure of human OCT3 in complex with inhibitor decynium-22
Descriptor: 1-ethyl-2-[(1-ethylquinolin-2-yl)methyl]quinoline, Solute carrier family 22 member 3
Authors:Khanppnavar, B, Korkhov, V.
Deposit date:2022-04-05
Release date:2022-11-09
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structural basis of organic cation transporter-3 inhibition.
Nat Commun, 13, 2022

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