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1YN3
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: truncated cell surface protein map-w
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN4
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: EapH1, ZINC ION
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
1YN5
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Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens
分子名称: EapH2
著者Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J.
登録日2005-01-23
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens.
J.Biol.Chem., 280, 2005
3D5R
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BU of 3d5r by Molmil
Crystal Structure of Efb-C (N138A) / C3d Complex
分子名称: Complement C3, Fibrinogen-binding protein
著者Geisbrecht, B.V.
登録日2008-05-16
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
3D5S
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BU of 3d5s by Molmil
Crystal Structure of Efb-C (R131A) / C3d Complex
分子名称: Complement C3, Fibrinogen-binding protein
著者Geisbrecht, B.V.
登録日2008-05-16
公開日2008-09-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
3L3O
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BU of 3l3o by Molmil
Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
著者Geisbrecht, B.V, Garcia, B.G.
登録日2009-12-17
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.405 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3KS2
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BU of 3ks2 by Molmil
Crystal Structure of Type-III Secretion Chaperone IpgC from Shigella flexneri (residues 10-155)
分子名称: Chaperone protein ipgC
著者Geisbrecht, B.V, Barta, M.L.
登録日2009-11-20
公開日2010-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Evidence for alternative quaternary structure in a bacterial Type III secretion system chaperone
Bmc Struct.Biol., 10, 2010
3L5N
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Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor, ...
著者Geisbrecht, B.V, Garcia, B.L.
登録日2009-12-22
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (7.536 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
3NMS
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Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement C3c
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
著者Geisbrecht, B.V, Garcia, B.L.
登録日2010-06-22
公開日2010-08-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
8TYP
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BU of 8typ by Molmil
Complement Protease C1s Inhibited by 6-(4-phenylpiperazin-1-yl)pyridine-3-carboximidamide
分子名称: 6-(4-phenylpiperazin-1-yl)pyridine-3-carboximidamide, Complement C1s subcomponent, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Geisbrecht, B.V.
登録日2023-08-25
公開日2023-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs.
J Immunol., 212, 2024
7TE3
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Crystal Structure of a Double Loop Deletion Mutant in gC1qR/C1qBP/HABP-1
分子名称: Complement component 1 Q subcomponent-binding protein, mitochondrial
著者Geisbrecht, B.V.
登録日2022-01-04
公開日2022-06-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献gC1qR/C1qBP/HABP-1: Structural Analysis of the Trimeric Core Region, Interactions With a Novel Panel of Monoclonal Antibodies, and Their Influence on Binding to FXII.
Front Immunol, 13, 2022
3OHX
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BU of 3ohx by Molmil
Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, Staphylococcal complement inhibitor
著者Geisbrecht, B.V, Garcia, B.L.
登録日2010-08-18
公開日2010-09-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.503 Å)
主引用文献Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b.
J.Mol.Biol., 402, 2010
6D69
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BU of 6d69 by Molmil
Crystal Structure of the NHL Repeat Region of D. melanogaster Thin
分子名称: GLYCEROL, NHL Repeat Region of D. melanogaster Thin
著者Ramyar, K.X, McWhorter, W.J, Geisbrecht, B.V.
登録日2018-04-20
公開日2019-04-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献DrosophilaTRIM32 cooperates with glycolytic enzymes to promote cell growth.
Elife, 9, 2020
5VJ0
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BU of 5vj0 by Molmil
Crystal Structure of heme-containing DyP Type Peroxidase from Enterobacter lignolyticus
分子名称: Dyp-type peroxidase family, PROTOPORPHYRIN IX CONTAINING FE
著者Meekins, D.A, Li, P, Geisbrecht, B.V.
登録日2017-04-17
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Mechanistic Insights into Dye-Decolorizing Peroxidase Revealed by Solvent Isotope and Viscosity Effects.
ACS Catal, 7, 2017
6VTM
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BU of 6vtm by Molmil
Human Cathepsin-G Inhibited by S. aureus EapH1
分子名称: Cathepsin G, MAP domain-containing protein, SULFATE ION
著者Herdendorf, T.J, Geisbrecht, B.V.
登録日2020-02-13
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Human Cathepsin-G Inhibited by S. aureus EapH1
J.Biol.Chem., 2020
5UZU
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BU of 5uzu by Molmil
Immune evasion by a Staphylococcal Peroxidase Inhibitor that blocks myeloperoxidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者de Jong, N, Geisbrecht, B.V, van Strijp, J, Haas, P, Nijland, R, Ramyar, K, Fevre, C, Guerra, F, Voyich-Kane, J, van Kessel, C, Garcia, B.
登録日2017-02-27
公開日2017-07-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Immune evasion by a staphylococcal inhibitor of myeloperoxidase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4NZL
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BU of 4nzl by Molmil
Extracellular proteins of Staphylococcus aureus inhibit the neutrophil serine proteases
分子名称: Neutrophil elastase, Uncharacterized protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Stapels, D.A.C, von Koeckritz-Blickwede, M, Ramyar, K.X, Bischoff, M, Milder, F, Ruyken, M, Scheepmaker, L, McWhorter, W.J, Herrmann, M, van Kessel, K.P.M, Geisbrecht, B.V, Rooijakkers, S.H.M.
登録日2013-12-12
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors.
Proc.Natl.Acad.Sci.USA, 111, 2014
5JXU
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Structural basis for the catalytic activity of Thermomonospora curvata heme-containing DyP-type peroxidase.
分子名称: Dyp-type peroxidase family, PROTOPORPHYRIN IX CONTAINING FE
著者Ramyar, K.X, Carlson, E.A, Li, P, Geisbrecht, B.V.
登録日2016-05-13
公開日2016-10-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献Identification of Surface-Exposed Protein Radicals and A Substrate Oxidation Site in A-Class Dye-Decolorizing Peroxidase from Thermomonospora curvata.
ACS Catal, 6, 2016
2HHI
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BU of 2hhi by Molmil
The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a novel class of beta-grasp proteins
分子名称: Immunogenic protein MPT64
著者Wang, Z, Potter, B.M, Gray, A.M, Sacksteder, K.A, Geisbrecht, B.V, Laity, J.H.
登録日2006-06-28
公開日2006-12-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The Solution Structure of Antigen MPT64 from Mycobacterium tuberculosis Defines a New Family of Beta-Grasp Proteins.
J.Mol.Biol., 366, 2007
6AZP
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BU of 6azp by Molmil
A Structurally Dynamic N-terminal Region Drives Function of the Staphylococcal Peroxidase Inhibitor (SPIN)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Ramyar, K.X, Geisbrecht, B.V.
登録日2017-09-11
公開日2017-12-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.291 Å)
主引用文献A structurally dynamic N-terminal region drives function of the staphylococcal peroxidase inhibitor (SPIN).
J. Biol. Chem., 293, 2018
1FCH
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BU of 1fch by Molmil
CRYSTAL STRUCTURE OF THE PTS1 COMPLEXED TO THE TPR REGION OF HUMAN PEX5
分子名称: PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR, PTS1-CONTAINING PEPTIDE
著者Gatto Jr, G.J, Geisbrecht, B.V, Gould, S.J, Berg, J.M.
登録日2000-07-18
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5.
Nat.Struct.Biol., 7, 2000
6BMT
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BU of 6bmt by Molmil
Crystal Structure of a Recombinant form of Human Myeloperoxidase Bound to an Inhibitor from Staphylococcus delphini
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Ploscariu, N.T, Geisbrecht, B.V.
登録日2017-11-15
公開日2018-01-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Identification and structural characterization of a novel myeloperoxidase inhibitor from Staphylococcus delphini.
Arch. Biochem. Biophys., 645, 2018
2NOJ
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Crystal structure of Ehp / C3d complex
分子名称: Complement C3, Efb homologous protein
著者Hammel, M, Geisbrecht, B.V.
登録日2006-10-25
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Characterization of Ehp, a Secreted Complement Inhibitory Protein from Staphylococcus aureus.
J.Biol.Chem., 282, 2007
3I86
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Crystal structure of the P60 Domain from M. avium subspecies paratuberculosis antigen MAP1204
分子名称: ISOPROPYL ALCOHOL, Putative uncharacterized protein
著者Ramyar, K.X, Lingle, C.K, McWhorter, W.J, Bouyain, S, Bannantine, J.P, Geisbrecht, B.V.
登録日2009-07-09
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Atypical structural features of two P60 family members from Mycobacterium avium subspecies paratuberculosis
To be Published
3GT2
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Crystal Structure of the P60 Domain from M. avium paratuberculosis Antigen MAP1272c
分子名称: 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION
著者Ramyar, K.X, Lingle, C.K, McWhorter, W.J, Bouyain, S, Bannantine, J.P, Geisbrecht, B.V.
登録日2009-03-27
公開日2010-04-07
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structures of Two P60-Family Antigens from Mycobacterium Avium Paratuberculosis
To be Published

 

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