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3ZLZ
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BU of 3zlz by Molmil
Lys6-linked tri-ubiquitin
Descriptor: UBIQUITIN, ZINC ION
Authors:Hospenthal, M.K, Freund, S.M.V, Komander, D.
Deposit date:2013-02-04
Release date:2013-04-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Assembly, Analysis and Architecture of Atypical Ubiquitin Chains
Nat.Struct.Mol.Biol., 20, 2013
4BCX
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BU of 4bcx by Molmil
gamma 2 adaptin EAR domain crystal structure
Descriptor: 1,3-PROPANDIOL, AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, IMIDAZOLE
Authors:Juergens, M.C, Voros, J, Rautureau, G, Shepherd, D, Pye, V.E, Muldoon, J, Johnson, C.M, Ashcroft, A, Freund, S.M.V, Ferguson, N.
Deposit date:2012-10-03
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
4BOS
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BU of 4bos by Molmil
Structure of OTUD2 OTU domain in complex with Ubiquitin K11-linked peptide
Descriptor: MAGNESIUM ION, NITRATE ION, OTUD2, ...
Authors:Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
Deposit date:2013-05-22
Release date:2013-07-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOP
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BU of 4bop by Molmil
Structure of OTUD1 OTU domain
Descriptor: OTU DOMAIN-CONTAINING PROTEIN 1, PHOSPHATE ION
Authors:Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOU
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BU of 4bou by Molmil
Structure of OTUD3 OTU domain
Descriptor: OTU DOMAIN-CONTAINING PROTEIN 3
Authors:Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOQ
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BU of 4boq by Molmil
Structure of OTUD2 OTU domain
Descriptor: GLYCEROL, UBIQUITIN THIOESTERASE OTU1
Authors:Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOZ
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BU of 4boz by Molmil
Structure of OTUD2 OTU domain in complex with K11-linked di ubiquitin
Descriptor: GLYCEROL, UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C
Authors:Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
Deposit date:2013-05-22
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4CH2
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BU of 4ch2 by Molmil
Low-salt crystal structure of a thrombin-GpIbalpha peptide complex
Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ...
Authors:Lechtenberg, B.C, Freund, S.M.V, Huntington, J.A.
Deposit date:2013-11-28
Release date:2013-12-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Gpibalpha Interacts Exclusively with Exosite II of Thrombin
J.Mol.Biol., 426, 2014
4CH8
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BU of 4ch8 by Molmil
High-salt crystal structure of a thrombin-GpIbalpha peptide complex
Descriptor: D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN, ...
Authors:Lechtenberg, B.C, Freund, S.M.V, Huntington, J.A.
Deposit date:2013-11-29
Release date:2013-12-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Gpibalpha Interacts Exclusively with Exosite II of Thrombin
J.Mol.Biol., 426, 2014
1AB7
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BU of 1ab7 by Molmil
NMR 15N RELAXATION AND STRUCTURAL STUDIES REVEAL CONFORMATIONAL EXCHANGE IN BARSTAR C40/82A, 30 STRUCTURES
Descriptor: BARSTAR
Authors:Wong, K.B, Fersht, A.R, Freund, S.M.V.
Deposit date:1997-02-04
Release date:1997-09-04
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:NMR 15N relaxation and structural studies reveal slow conformational exchange in barstar C40/82A.
J.Mol.Biol., 268, 1997
1BTB
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BU of 1btb by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE AND 13C ASSIGNMENTS OF BARSTAR USING NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: BARSTAR
Authors:Lubienski, M.J, Bycroft, M, Freund, S.M.V, Fersht, A.R.
Deposit date:1994-05-09
Release date:1994-07-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Three-dimensional solution structure and 13C assignments of barstar using nuclear magnetic resonance spectroscopy.
Biochemistry, 33, 1994
1ZTR
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BU of 1ztr by Molmil
Solution structure of Engrailed homeodomain L16A mutant
Descriptor: Segmentation polarity homeobox protein engrailed
Authors:Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R.
Deposit date:2005-05-27
Release date:2005-10-18
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Solution structure of a protein denatured state and folding intermediate.
Nature, 437, 2005
2BIV
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BU of 2biv by Molmil
Crystal structure of the wild-type MBT domains of Human SCML2
Descriptor: IODIDE ION, SEX COMB ON MIDLEG-LIKE PROTEIN 2, SODIUM ION
Authors:Santiveri, C.M, Allen, M.D, Sait, F, Bycroft, M.
Deposit date:2005-01-26
Release date:2005-02-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Malignant Brain Tumor Repeats of Human Scml2 Bind to Peptides Containing Monomethylated Lysine.
J.Mol.Biol., 382, 2008
6Z5L
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BU of 6z5l by Molmil
Helical reconstruction of influenza A virus M1 in complex with nucleic acid.
Descriptor: Matrix protein 1
Authors:Xiong, X, Qu, K, Briggs, J.A.G.
Deposit date:2020-05-26
Release date:2020-10-14
Last modified:2020-12-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The native structure of the assembled matrix protein 1 of influenza A virus.
Nature, 587, 2020
4UZM
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BU of 4uzm by Molmil
Shotgun proteolysis: A practical application
Descriptor: PUTATIVE MEMBRANE PROTEIN IGAA HOMOLOG
Authors:Allen, M.D, Bycroft, M, Freund, S.M.V, Christ, D.
Deposit date:2014-09-05
Release date:2014-09-17
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:Solution Structure of a Soluble Fragment Derived from a Membrane Protein by Shotgun Proteolysis.
Protein Eng.Des.Sel., 28, 2015
2L9N
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BU of 2l9n by Molmil
Structure of the human Shwachman-Bodian-Diamond syndrome (SBDS) protein
Descriptor: Ribosome maturation protein SBDS
Authors:Hilcenko, C, Freund, S.M.V, Warren, A.J.
Deposit date:2011-02-21
Release date:2011-05-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome.
Genes Dev., 25, 2011
7OWD
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BU of 7owd by Molmil
Structure of CYLD CAP-Gly3 (467-552) bound to Ub; tetragonal space group
Descriptor: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase CYLD
Authors:Elliott, P.R, Komander, D.
Deposit date:2021-06-17
Release date:2021-10-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
7OWC
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BU of 7owc by Molmil
Structure of CYLD CAP-Gly3 (467-565) bound to Ub; orthorhobic space group
Descriptor: Deubiquitinating enzyme CYLD, Ubiquitin-60S ribosomal protein L40
Authors:Elliott, P.R, Komander, D.
Deposit date:2021-06-17
Release date:2021-10-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
7Q6D
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BU of 7q6d by Molmil
E. coli FtsA 1-405 ATP 3 Ni
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION, ...
Authors:Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2021-11-06
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Nat Microbiol, 7, 2022
7Q6G
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BU of 7q6g by Molmil
Xenorhabdus poinarii FtsA 1-396 ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION
Authors:Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2021-11-07
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Nat Microbiol, 7, 2022
7Q6I
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BU of 7q6i by Molmil
Vibrio maritimus FtsA 1-396 ATP and FtsN 1-29, bent tetramers in double filament arrangement
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, Cell division protein FtsN (polyAla model), ...
Authors:Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2021-11-07
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Nat Microbiol, 7, 2022
7Q6F
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BU of 7q6f by Molmil
Vibrio maritimus FtsA 1-396 ATP, double filament
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION
Authors:Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J.
Deposit date:2021-11-07
Release date:2022-09-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Nat Microbiol, 7, 2022
7B1H
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BU of 7b1h by Molmil
Monoclinic P21 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-24
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
7B1F
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BU of 7b1f by Molmil
Orthorhombic P212121 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-24
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
7B1J
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BU of 7b1j by Molmil
Orthorhombic P21212 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
Authors:Fischer, E, Bellini, D, Barford, D.
Deposit date:2020-11-25
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021

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