4UDR
 
 | | Crystal structure of the H467A mutant of 5-hydroxymethylfurfural oxidase (HMFO) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE | | Authors: | Dijkman, W, Binda, C, Fraaije, M, Mattevi, A. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis, 5, 2015
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4UDQ
 | | Crystal structure of 5-hydroxymethylfurfural oxidase (HMFO) in the reduced state | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE | | Authors: | Dijkman, W, Binda, C, Fraaije, M, Mattevi, A. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis, 5, 2015
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4UDP
 | | Crystal structure of 5-hydroxymethylfurfural oxidase (HMFO) in the oxidized state | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE | | Authors: | Dijkman, W, Binda, C, Fraaije, M, Mattevi, A. | | Deposit date: | 2014-12-11 | | Release date: | 2015-03-18 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis, 5, 2015
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7AL4
 | | Ancestral Flavin-containing monooxygenase (FMO) 1 (mammalian) | | Descriptor: | Ancestral Flavin-containing monooxygenase 1 (mammalian), CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Nicoll, C.R, Mattevi, A. | | Deposit date: | 2020-10-05 | | Release date: | 2020-12-30 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties.
J.Biol.Chem., 296, 2020
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6HNS
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6SEM
 | | Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 2 | | Descriptor: | Ancestral Flavin-containing monooxygenase (FMO) 2, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A. | | Deposit date: | 2019-07-30 | | Release date: | 2019-12-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
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6SE3
 | | Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 3-6 | | Descriptor: | Ancestral Flavin-containing monooxygenase (FMO) 3-6, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A. | | Deposit date: | 2019-07-29 | | Release date: | 2019-12-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
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6SF0
 | | Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 2 in the presence of NADP+ | | Descriptor: | Ancestral Flavin-containing monooxygenase (FMO) 2, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A. | | Deposit date: | 2019-07-30 | | Release date: | 2019-12-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
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6SEK
 | | Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 5 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ancestral Flavin-containing monooxygenase 5, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A. | | Deposit date: | 2019-07-30 | | Release date: | 2019-12-25 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
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5O0X
 | | Crystal structure of dehydrogenase domain of Cylindrospermum stagnale NADPH-Oxidase 5 (NOX5) | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Magnani, F, Nenci, S, Mattevi, A. | | Deposit date: | 2017-05-17 | | Release date: | 2017-06-28 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures and atomic model of NADPH oxidase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5O0T
 | | CRYSTAL STRUCTURE OF TRANS-MEMBRANE DOMAIN OF Cylindrospermum stagnale NADPH-OXIDASE 5 (NOX5) | | Descriptor: | DECANE, DI(HYDROXYETHYL)ETHER, EICOSANE, ... | | Authors: | Magnani, F, Nenci, S, Mattevi, A. | | Deposit date: | 2017-05-17 | | Release date: | 2017-06-28 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structures and atomic model of NADPH oxidase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1AHZ
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1AHV
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1AHU
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7YWU
 | | Eugenol oxidase from rhodococcus jostii: mutant S81H, A423M, H434Y, S394V, I445D, S518P | | Descriptor: | 2-methoxy-4-(prop-2-en-1-yl)phenol, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | Authors: | Alvigini, L, Mattevi, A. | | Deposit date: | 2022-02-14 | | Release date: | 2022-11-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound.
Nat Commun, 13, 2022
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7YWV
 | | Eugenol oxidase from rhodococcus jostii: mutant S81H, D151E, A423M, H434Y, S394V, Q425S, I445D, S518P | | Descriptor: | 2-methoxy-4-(prop-2-en-1-yl)phenol, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Alvigini, L, Mattevi, A. | | Deposit date: | 2022-02-14 | | Release date: | 2022-11-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound.
Nat Commun, 13, 2022
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7PBI
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7PBG
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6GQI
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8OT8
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1E0Y
 | | Structure of the D170S/T457E double mutant of vanillyl-alcohol oxidase | | Descriptor: | ALPHA,ALPHA,ALPHA-TRIFLUORO-P-CRESOL, FLAVIN-ADENINE DINUCLEOTIDE, VANILLYL-ALCOHOL OXIDASE | | Authors: | Van Der heuvel, R.H.H, Van Berkel, W.J.H, Mattevi, A. | | Deposit date: | 2000-04-11 | | Release date: | 2000-04-12 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Inversion of Stereospecificity in Vanillyl-Alcohol Oxidase
Proc.Natl.Acad.Sci.USA, 97, 2000
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1VAO
 | | STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE | | Descriptor: | ACETATE ION, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Mattevi, A. | | Deposit date: | 1997-04-10 | | Release date: | 1997-10-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity.
Structure, 5, 1997
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1W1S
 | | Plant Cytokinin Dehydrogenase in Complex with Benzylaminopurine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOKININ DEHYDROGENASE, ... | | Authors: | Malito, E, Mattevi, A. | | Deposit date: | 2004-06-23 | | Release date: | 2004-08-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis
J.Mol.Biol., 341, 2004
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1W1Q
 | | Plant Cytokinin Dehydrogenase in Complex with Isopentenyladenine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOKININ DEHYDROGENASE 1, ... | | Authors: | Malito, E, Mattevi, A. | | Deposit date: | 2004-06-23 | | Release date: | 2004-08-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structures of Michaelis and Product Complexes of Plant Cytokinin Dehydrogenase: Implications for Flavoenzyme Catalysis
J.Mol.Biol., 341, 2004
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1W4X
 | | Phenylacetone Monooxygenase, a Baeyer-Villiger Monooxygenase | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, PHENYLACETONE MONOOXYGENASE, SULFATE ION | | Authors: | Malito, E, Alfieri, A, Mattevi, A. | | Deposit date: | 2004-08-03 | | Release date: | 2004-09-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of a Baeyer-Villiger Monooxygenase
Proc.Natl.Acad.Sci.USA, 101, 2004
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