Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1NL4
DownloadVisualize
BU of 1nl4 by Molmil
Crystal Structure of Rat Farnesyl Transferase in Complex With A Potent Biphenyl Inhibitor
分子名称: 4-[(3-CYANO-BENZYL)-(3-METHYL-3H-IMIDAZOL-4-YLMETHYL)-AMINO]-2-NAPHTHALEN-1-YL-BENZONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ...
著者Curtin, M.L, Florjancic, A.S, Cohen, J, Gu, W.-J, Frost, D.J, Muchmore, S.W, Sham, H.L.
登録日2003-01-06
公開日2003-02-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel and Selective Imidazole-containing Biphenyl Inhibitors of Protein Farnesyltransferase
BIOORG.MED.CHEM.LETT., 13, 2003
4IQ6
DownloadVisualize
BU of 4iq6 by Molmil
Gsk-3beta with inhibitor 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine
分子名称: 6-chloro-N-cyclohexyl-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-amine, Glycogen synthase kinase-3 beta
著者Tong, Y, Stewart, K.D, Florjancic, A.S, Harlan, J.E, Merta, P.J, Przytulinska, M, Soni, N, Swinger, K.S, Zhu, H, Johnson, E.F, Shoemaker, A.R, Penning, T.D.
登録日2013-01-10
公開日2013-04-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195.
ACS Med Chem Lett, 4, 2013
7M2F
DownloadVisualize
BU of 7m2f by Molmil
CDK2 with compound 14 inhibitor with carboxylate
分子名称: Cyclin-dependent kinase 2, [(1r,4r)-4-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}cyclohexyl]acetic acid
著者Longenecker, K.L, Qiu, W, Korepanova, A, Tong, Y.
登録日2021-03-16
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.632 Å)
主引用文献Balancing Properties with Carboxylates: A Lead Optimization Campaign for Selective and Orally Active CDK9 Inhibitors.
Acs Med.Chem.Lett., 12, 2021

218853

件を2024-04-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon