1F3E
 
 | | A NEW TARGET FOR SHIGELLOSIS: RATIONAL DESIGN AND CRYSTALLOGRAPHIC STUDIES OF INHIBITORS OF TRNA-GUANINE TRANSGLYCOSYLASE | | 分子名称: | 3,5-DIAMINOPHTHALHYDRAZIDE, QUEUINE TRNA-RIBOSYLTRANSFERASE, ZINC ION | | 著者 | Graedler, U, Gerber, H.-D, Goodenough-Lashua, D.M, Garcia, G.A.G, Ficner, R, Reuter, K, Stubbs, M.T, Klebe, G. | | 登録日 | 2000-06-02 | | 公開日 | 2000-06-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase.
J.Mol.Biol., 306, 2001
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6RMC
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative mRNA splicing factor, ... | | 著者 | Hamann, F, Neumann, P, Schmitt, A, Ficner, R. | | 登録日 | 2019-05-06 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RMA
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Hamann, F, Neumann, P, Ficner, R. | | 登録日 | 2019-05-06 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6RM8
 | | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Hamann, F, Neumann, P, Ficner, R. | | 登録日 | 2019-05-06 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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1WKE
 | | TRNA-GUANINE TRANSGLYCOSYLASE | | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | | 登録日 | 1996-08-06 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
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1WKD
 | | TRNA-GUANINE TRANSGLYCOSYLASE | | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | | 登録日 | 1996-08-06 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
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1WKF
 | | TRNA-GUANINE TRANSGLYCOSYLASE | | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | | 登録日 | 1996-08-06 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
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1FJH
 | | THE CRYSTAL STRUCTURE OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY | | 分子名称: | 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE | | 著者 | Grimm, C, Ficner, R, Maser, E, Klebe, G, Reuter, K. | | 登録日 | 2000-08-08 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family.
J.Biol.Chem., 275, 2000
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1FK8
 | | THE CRYSTAL STRUCTURE OF THE BINARY COMPLEX WITH NAD OF 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE FROM COMAMONAS TESTOSTERONI, A MEMBER OF THE SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY | | 分子名称: | 3ALPHA-HYDROXYSTEROID DEHYDROGENASE/CARBONYL REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Grimm, C, Ficner, R, Maser, E, Klebe, G, Reuter, K. | | 登録日 | 2000-08-09 | | 公開日 | 2001-01-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family.
J.Biol.Chem., 275, 2000
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5D0U
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8C4J
 | | CdaA-compound 4 complex | | 分子名称: | 5-methylpyrimidin-4-amine, CHLORIDE ION, Diadenylate cyclase | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8C4P
 | | CdaA-compound 7 complex | | 分子名称: | CHLORIDE ION, Diadenylate cyclase, ~{N}-[5-(2-azanyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]ethanamide | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8C4N
 | | CdaA-AMP complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Diadenylate cyclase, ... | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8C4M
 | | CdaA-Adenosine complex | | 分子名称: | ADENOSINE, CHLORIDE ION, Diadenylate cyclase | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8C4R
 | | CdaA-adenine complex | | 分子名称: | ADENINE, CHLORIDE ION, Diadenylate cyclase | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8C4O
 | | CdaA-ATP complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Diadenylate cyclase, ... | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8C4Q
 | | CdaA-Apo | | 分子名称: | CHLORIDE ION, Diadenylate cyclase | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8CNT
 | | Structure of the DEAH-box helicase Prp16 in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ... | | 著者 | Garbers, T.B, Neumann, P, Ficner, R. | | 登録日 | 2023-02-24 | | 公開日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of Prp16 in complex with ADP.
Acta Crystallogr.,Sect.F, 79, 2023
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4XRI
 | | Crystal Structure of Importin Beta in an Ammonium Sulfate Condition | | 分子名称: | GLYCEROL, Putative uncharacterized protein, SULFATE ION | | 著者 | Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A. | | 登録日 | 2015-01-21 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Impact of the crystallization condition on importin-beta conformation.
Acta Crystallogr D Struct Biol, 72, 2016
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4XRK
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4ZEM
 | | Crystal structure of eIF2B beta from Chaetomium thermophilum | | 分子名称: | Translation initiation factor eIF2b-like protein,Translation initiation factor eIF2b-like protein | | 著者 | Kuhle, B, Ficner, R. | | 登録日 | 2015-04-20 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Architecture of the eIF2B regulatory subcomplex and its implications for the regulation of guanine nucleotide exchange on eIF2.
Nucleic Acids Res., 43, 2015
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4ZEO
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1V0E
 | | Endosialidase of Bacteriophage K1F | | 分子名称: | ENDO-ALPHA-SIALIDASE, PHOSPHATE ION | | 著者 | Stummeyer, K, Dickmanns, A, Muehlenhoff, M, Gerady-Schahn, R, Ficner, R. | | 登録日 | 2004-03-28 | | 公開日 | 2004-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F
Nat.Struct.Mol.Biol., 12, 2005
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1V0F
 | | Endosialidase of Bacteriophage K1F in complex with oligomeric alpha-2,8-sialic acid | | 分子名称: | ENDO-ALPHA-SIALIDASE, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, N-acetyl-beta-neuraminic acid, ... | | 著者 | Stummeyer, K, Dickmanns, A, Muehlenhoff, M, Gerady-Schahn, R, Ficner, R. | | 登録日 | 2004-03-28 | | 公開日 | 2004-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F
Nat.Struct.Mol.Biol., 12, 2005
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1QR0
 | | CRYSTAL STRUCTURE OF THE 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP-COENZYME A COMPLEX | | 分子名称: | 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP, COENZYME A, MAGNESIUM ION | | 著者 | Reuter, K, Mofid, R.M, Marahiel, A.M, Ficner, R. | | 登録日 | 1999-06-17 | | 公開日 | 1999-12-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily.
EMBO J., 18, 1999
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