1DRZ
| U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX | Descriptor: | MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ... | Authors: | Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A. | Deposit date: | 1998-09-01 | Release date: | 1999-02-16 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of a hepatitis delta virus ribozyme. Nature, 395, 1998
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1AN2
| RECOGNITION BY MAX OF ITS COGNATE DNA THROUGH A DIMERIC B/HLH/Z DOMAIN | Descriptor: | DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3'), PROTEIN (TRANSCRIPTION FACTOR MAX (TF MAX)) | Authors: | Ferre-D'Amare, A.R, Prendergast, G.C, Ziff, E.B, Burley, S.K. | Deposit date: | 1996-09-06 | Release date: | 1997-09-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature, 363, 1993
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1AN4
| STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF | Descriptor: | DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR) | Authors: | Ferre-D'Amare, A.R, Pognonec, P, Roeder, R.G, Burley, S.K. | Deposit date: | 1997-03-15 | Release date: | 1997-09-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure and function of the b/HLH/Z domain of USF. EMBO J., 13, 1994
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6PQ7
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4LCK
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2APO
| Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex | Descriptor: | POTASSIUM ION, Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ... | Authors: | Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R. | Deposit date: | 2005-08-16 | Release date: | 2005-11-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs. Nat.Struct.Mol.Biol., 12, 2005
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4W90
| Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... | Authors: | Jones, C.P, Ferre-D'Amare, A.R. | Deposit date: | 2014-08-26 | Release date: | 2014-10-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.118 Å) | Cite: | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA. Embo J., 33, 2014
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4XNR
| Vibrio Vulnificus Adenine Riboswitch Aptamer Domain, Synthesized by Position-selective Labeling of RNA (PLOR), in Complex with Adenine | Descriptor: | ADENINE, MAGNESIUM ION, Vibrio Vulnificus Adenine Riboswitch | Authors: | Zhang, J, Liu, Y, Wang, Y.-X, Ferre-D'Amare, A.R. | Deposit date: | 2015-01-16 | Release date: | 2015-05-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Synthesis and applications of RNAs with position-selective labelling and mosaic composition. Nature, 522, 2015
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6E81
| Crystal structure of the Corn aptamer in complex with ThT | Descriptor: | 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, POTASSIUM ION, RNA (36-MER) | Authors: | Sjekloca, L, Ferre-D'Amare, A.R. | Deposit date: | 2018-07-27 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.721 Å) | Cite: | Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence. Cell Chem Biol, 26, 2019
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7SXP
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1K8W
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1ZL3
| Coupling of active site motions and RNA binding | Descriptor: | 5'-R(*GP*GP*CP*AP*AP*CP*GP*GP*UP*(FLO) UP*CP*GP*AP*UP*CP*CP*CP*GP*UP*UP*GP*C)-3', SULFATE ION, tRNA pseudouridine synthase B | Authors: | Hoang, C, Hamilton, C.S, Mueller, E.G, Ferre-D'Amare, A.R. | Deposit date: | 2005-05-05 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Precursor complex structure of pseudouridine synthase TruB suggests coupling of active site perturbations to an RNA-sequestering peripheral protein domain Protein Sci., 14, 2005
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4W92
| Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, 1,2-ETHANEDIOL, C-di-AMP ribsoswitch, ... | Authors: | Jones, C.P, Ferre-D'Amare, A.R. | Deposit date: | 2014-08-26 | Release date: | 2014-10-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.209 Å) | Cite: | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA. Embo J., 33, 2014
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4XK0
| Crystal structure of a tetramolecular RNA G-quadruplex in potassium | Descriptor: | BARIUM ION, POTASSIUM ION, RNA (5'-(*UP*GP*GP*GP*GP*U)-3') | Authors: | Chen, M.C, Murat, P, Abecassis, K.A, Ferre-D'Amare, A.R, Balasubramanian, S. | Deposit date: | 2015-01-09 | Release date: | 2015-02-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase. Nucleic Acids Res., 43, 2015
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2AQC
| NMR Structural analysis of archaeal Nop10 | Descriptor: | Ribosome biogenesis protein Nop10, ZINC ION | Authors: | Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R. | Deposit date: | 2005-08-17 | Release date: | 2005-11-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs. Nat.Struct.Mol.Biol., 12, 2005
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2AQA
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6WZS
| Fusibacterium ulcerans ZTP riboswitch bound to m-1-pyridinyl AICA | Descriptor: | 5-amino-1-(pyridin-3-yl)-1H-imidazole-4-carboxamide, Fusibacterium ulcerans ZTP riboswitch, MAGNESIUM ION, ... | Authors: | Pichling, P, Jones, C.P, Ferre-D'Amare, A.R, Tran, B. | Deposit date: | 2020-05-14 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design. Cell Chem Biol, 27, 2020
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6WZR
| Fusibacterium ulcerans ZTP riboswitch bound to p-1-pyridinyl AICA | Descriptor: | 5-amino-1-(pyridin-4-yl)-1H-imidazole-4-carboxamide, Fusibacterium ulcerans ZTP riboswitch, MAGNESIUM ION, ... | Authors: | Pichling, P, Jones, C.P, Ferre-D'Amare, A.R, Tran, B. | Deposit date: | 2020-05-14 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design. Cell Chem Biol, 27, 2020
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1SB7
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3IWN
| Co-crystal structure of a bacterial c-di-GMP riboswitch | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C-di-GMP riboswitch, U1 small nuclear ribonucleoprotein A | Authors: | Kulshina, N, Baird, N.J, Ferre-D'Amare, A.R. | Deposit date: | 2009-09-02 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch. Nat.Struct.Mol.Biol., 16, 2009
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3K1V
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3K0J
| Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module | Descriptor: | MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ... | Authors: | Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R. | Deposit date: | 2009-09-24 | Release date: | 2009-12-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch. Rna, 16, 2010
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3V7E
| Crystal structure of YbxF bound to the SAM-I riboswitch aptamer | Descriptor: | COBALT HEXAMMINE(III), MAGNESIUM ION, Ribosome-associated protein L7Ae-like, ... | Authors: | Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. | Deposit date: | 2011-12-21 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops. Rna, 18, 2012
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3V7Q
| Crystal structure of B. subtilis YlxQ at 1.55 A resolution | Descriptor: | CITRIC ACID, POTASSIUM ION, Probable ribosomal protein ylxQ | Authors: | Baird, N.J, Zhang, J, Hamma, T, Ferre-D'Amare, A.R. | Deposit date: | 2011-12-21 | Release date: | 2012-03-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | YbxF and YlxQ are bacterial homologs of L7Ae and bind K-turns but not K-loops. Rna, 18, 2012
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5BJO
| Crystal structure of the Corn RNA aptamer in complex with DFHO, site-specific 5-iodo-U | Descriptor: | (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Warner, K.D, Song, W, Filonov, G.S, Jaffrey, S.R, Ferre-D'Amare, A.R. | Deposit date: | 2016-08-21 | Release date: | 2017-09-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | A homodimer interface without base pairs in an RNA mimic of red fluorescent protein. Nat. Chem. Biol., 13, 2017
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