8CJ4
| Crystal structure of ClpP from Staphylococcus epidermidis, tetradecamer | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit | Authors: | Alves Franca, B, Rohde, H, Betzel, C. | Deposit date: | 2023-02-12 | Release date: | 2024-01-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds. Sci Rep, 14, 2024
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6FDG
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4WFD
| Structure of the Rrp6-Rrp47-Mtr4 interaction | Descriptor: | ATP-dependent RNA helicase DOB1, Exosome complex exonuclease RRP6, Exosome complex protein LRP1, ... | Authors: | Schuch, B, Conti, E. | Deposit date: | 2014-09-14 | Release date: | 2014-10-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. Embo J., 33, 2014
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4WFC
| Structure of the Rrp6-Rrp47 interaction | Descriptor: | Exosome complex exonuclease RRP6, Exosome complex protein LRP1, SULFATE ION | Authors: | Schuch, B, Conti, E. | Deposit date: | 2014-09-14 | Release date: | 2014-10-29 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. Embo J., 33, 2014
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8S8X
| SARS-CoV-2 nsp10-16 methyltransferase in complex with Toyocamycin and m7GpppA-RNA (Cap0-RNA) | Descriptor: | 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-amino-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, ... | Authors: | Kremling, V, Sprenger, J, Oberthuer, D, Scheer, T.E.S. | Deposit date: | 2024-03-07 | Release date: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug development To Be Published
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8S8W
| SARS-CoV-2 nsp10-16 methyltransferase in complex with Sangivamycin and m7GpppA-RNA (Cap0-RNA) | Descriptor: | 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Kremling, V, Sprenger, J, Oberthuer, D, Scheer, T.E.S. | Deposit date: | 2024-03-07 | Release date: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug development To Be Published
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3ZRI
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3ZRJ
| Complex of ClpV N-domain with VipB peptide | Descriptor: | 1,2-ETHANEDIOL, CLPB PROTEIN, VIPB | Authors: | Lenherr, E.D, Kopp, J, Sinning, I. | Deposit date: | 2011-06-16 | Release date: | 2011-07-06 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Molecular Basis for the Unique Role of the Aaa+ Chaperone Clpv in Type Vi Protein Secretion. J.Biol.Chem., 286, 2011
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7AQE
| Structure of SARS-CoV-2 Main Protease bound to UNC-2327 | Descriptor: | 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Guenther, S, Reinke, P, Meents, A. | Deposit date: | 2020-10-21 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
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8BS1
| Room-temperature structure of SARS-CoV-2 Main protease at atmospheric pressure | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Lieske, J, Saouane, S, Guenther, S, Reinke, P.Y.A, Rahmani Mashhour, A, Meents, A. | Deposit date: | 2022-11-24 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | High-pressure macromolecular crystallography to explore the conformational space of proteins To Be Published
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8BS2
| Room-temperature structure of SARS-CoV-2 Main protease at 104 MPa helium gas pressure in a sapphire capillary | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Lieske, J, Saouane, S, Guenther, S, Reinke, P.Y.A, Rahmani Mashhour, A, Meents, A. | Deposit date: | 2022-11-24 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | High-pressure macromolecular crystallography to explore the conformational space of proteins To Be Published
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8BRZ
| Room-temperature structure of Pedobacter heparinus N-acetylglucosamine 2-epimerase at 52 MPa helium gas pressure in a sapphire capillary | Descriptor: | CHLORIDE ION, N-acylglucosamine 2-epimerase, PHOSPHATE ION | Authors: | Lieske, J, Saouane, S, Assmann, M, Zaun, H, Kuballa, J, Meents, A. | Deposit date: | 2022-11-24 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High-pressure macromolecular crystallography to explore the conformational space of proteins To Be Published
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8BRY
| Room-temperature structure of Pedobacter heparinus N-acetylglucosamine 2-epimerase at atmospheric pressure | Descriptor: | CHLORIDE ION, N-acylglucosamine 2-epimerase, PHOSPHATE ION | Authors: | Lieske, J, Saouane, S, Assmann, M, Zaun, H, Kuballa, J, Meents, A. | Deposit date: | 2022-11-24 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High-pressure macromolecular crystallography to explore the conformational space of proteins To Be Published
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8BS0
| Room-temperature structure of Pedobacter heparinus N-acetylglucosamine 2-epimerase at 80 MPa helium gas pressure in a sapphire capillary | Descriptor: | CHLORIDE ION, N-acylglucosamine 2-epimerase, PHOSPHATE ION | Authors: | Lieske, J, Saouane, S, Assmann, M, Zaun, H, Kuballa, J, Meents, A. | Deposit date: | 2022-11-24 | Release date: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High-pressure macromolecular crystallography to explore the conformational space of proteins To Be Published
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8OTO
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8OV3
| SARS-CoV-2 nsp10-16 methyltransferase in complex with 5-Iodotubercidin | Descriptor: | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, ... | Authors: | Kremling, V, Sprenger, J, Oberthuer, D. | Deposit date: | 2023-04-25 | Release date: | 2023-05-10 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structures of Tubercidin and Adenosine bound to the active site of the SARS-CoV-2 methyltransferase nsp10-16 To Be Published
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8OV1
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8OV4
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8OV2
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8OSX
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8OTR
| SARS-CoV-2 nsp10-16 methyltransferase in complex with SAM analog BDH 33959089 | Descriptor: | (2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-(1-methylpiperidin-4-yl)-3,4-bis(oxidanyl)oxolane-2-carboxamide, 1,2-ETHANEDIOL, 2'-O-methyltransferase nsp16, ... | Authors: | Kremling, V, Sprenger, J, Oberthuer, D. | Deposit date: | 2023-04-21 | Release date: | 2023-05-24 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal structures of Tubercidin and Adenosine bound to the active site of the SARS-CoV-2 methyltransferase nsp10-16 To Be Published
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8QYF
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8JEE
| Crystal Structure of Human Carbonic Anhydrase II In-complex with Levosulpiride at 2.96 A Resolution | Descriptor: | Carbonic anhydrase 2, GLYCEROL, Levosulpiride, ... | Authors: | Rasheed, S, Huda, N, Falke, S, Fisher, S.Z, Ahmad, M.S. | Deposit date: | 2023-05-15 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Crystal Structure of Human Carbonic Anhydrase II In-complex with Levosulpiride at 2.96 A Resolution To Be Published
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7ALZ
| GqqA- a novel type of quorum quenching acylases | Descriptor: | PHENYLALANINE, Prephenate dehydratase | Authors: | Werner, N, Betzel, C. | Deposit date: | 2020-10-07 | Release date: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity. Sci Rep, 11, 2021
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7AM0
| GqqA- a novel type of quorum quenching acylases | Descriptor: | PHENYLALANINE, Prephenate dehydratase | Authors: | Werner, N, Betzel, C. | Deposit date: | 2020-10-07 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity. Sci Rep, 11, 2021
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