1YMC
 
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1YMB
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1PLG
 | | EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID | | 分子名称: | IGG2A=KAPPA= | | 著者 | Evans, S.V, Sigurskjold, B.W, Jennings, H.J, Brisson, J.-R, Tse, W.C, To, R, Altman, E, Frosch, M, Weisgerber, C, Kratzin, H, Klebert, S, Vaesen, M, Bitter-Suermann, D, Rose, D.R, Young, N.M, Bundle, D.R. | | 登録日 | 1995-04-24 | | 公開日 | 1996-04-03 | | 最終更新日 | 2012-02-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.
Biochemistry, 34, 1995
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5KXD
 | | Wisteria floribunda lectin in complex with GalNAc(beta1-4)GlcNAc (LacdiNAc) at pH 6.5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | | 著者 | Evans, S.V, Haji-Ghassemi, O. | | 登録日 | 2016-07-20 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[ beta 14]GlcNAc), by Wisteria floribunda Agglutinin.
J.Biol.Chem., 291, 2016
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5KXC
 | | Wisteria floribunda lectin in complex with GalNAc(beta1-4)GlcNAc (LacdiNAc) at pH 8.5. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE (II) ION, ... | | 著者 | Evans, S.V, Haji-Ghassemi, O. | | 登録日 | 2016-07-20 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[ beta 14]GlcNAc), by Wisteria floribunda Agglutinin.
J.Biol.Chem., 291, 2016
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5KXB
 | | Wisteria floribunda lectin in complex with GalNAc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, MANGANESE (II) ION, ... | | 著者 | Evans, S.V, Haji-Ghassemi, O. | | 登録日 | 2016-07-20 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[ beta 14]GlcNAc), by Wisteria floribunda Agglutinin.
J.Biol.Chem., 291, 2016
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5KXE
 | | Wisteria floribunda lectin in complex with GalNAc(beta1-4)GlcNAc (LacdiNAc) at pH 4.2 | | 分子名称: | CALCIUM ION, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Evans, S.V, Haji-Ghassemi, O. | | 登録日 | 2016-07-20 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[ beta 14]GlcNAc), by Wisteria floribunda Agglutinin.
J.Biol.Chem., 291, 2016
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6C5H
 | | S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Evans, S.V, Haji-Ghassemi, O. | | 登録日 | 2018-01-16 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019
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6C5I
 | | Unliganded S25-5 Fab | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Evans, S.V, Haji-Ghassemi, O. | | 登録日 | 2018-01-16 | | 公開日 | 2019-01-09 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019
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1R24
 | | FAB FROM MURINE IGG3 KAPPA | | 分子名称: | PROTEIN (IGG3-KAPPA ANTIBODY (HEAVY CHAIN)), PROTEIN (IGG3-KAPPA ANTIBODY (LIGHT CHAIN)) | | 著者 | Evans, S.V. | | 登録日 | 1998-11-05 | | 公開日 | 1999-11-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains.
J.Biol.Chem., 274, 1999
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2RIY
 | | B-specific-1,3-galactosyltransferase (GTB)+H-antigen acceptor | | 分子名称: | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside | | 著者 | Evans, S.V, Alfaro, J.A. | | 登録日 | 2007-10-13 | | 公開日 | 2008-02-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283, 2008
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2RJ4
 | | B-specific alpha-1,3-galactosyltransferase G176R +UDP+ADA | | 分子名称: | Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... | | 著者 | Evans, S.V, Alfaro, J.A. | | 登録日 | 2007-10-14 | | 公開日 | 2008-02-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283, 2008
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2RIX
 | | B-specific-1,3-galactosyltransferase)(GTB) + UDP | | 分子名称: | GLYCEROL, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, ... | | 著者 | Evans, S.V, Alfaro, J.A. | | 登録日 | 2007-10-13 | | 公開日 | 2008-02-05 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283, 2008
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2RJ9
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2RJ0
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2RJ8
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2RIT
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2RJ7
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2RJ1
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2RJ6
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2RJ5
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2RIZ
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1BZ7
 | | FAB FRAGMENT FROM MURINE ASCITES | | 分子名称: | PROTEIN (ANTIBODY R24 (HEAVY CHAIN)), PROTEIN (ANTIBODY R24 (LIGHT CHAIN)) | | 著者 | Kaminski, M.J, Mackenzie, C.R, Mooibroek, M.J, Dahms, T.E.S, Hirama, T, Houghton, A.N, Chapman, P.B, Evans, S.V. | | 登録日 | 1998-11-06 | | 公開日 | 1999-11-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains.
J.Biol.Chem., 274, 1999
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1JV5
 | | Anti-blood group A Fv | | 分子名称: | Ig chain heavy chain precursor V region, Ig kappa chain precursor V region | | 著者 | Thomas, R, Patenaude, S.I, MacKenzie, C.R, To, R, Hirama, T, Young, N.M, Evans, S.V. | | 登録日 | 2001-08-28 | | 公開日 | 2002-01-09 | | 最終更新日 | 2018-04-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of an anti-blood group A Fv and improvement of its binding affinity without loss of specificity.
J.Biol.Chem., 277, 2002
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7SV3
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