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Crystal structure of HCV NS5B RNA polymerase complexed with a novel non-competitive inhibitor.
分子名称:	3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE, Hepatitis C virus NS5B RNA polymerase
著者	Love, R.A, Parge, H.E, Yu, X, Hickey, M.J, Diehl, W, Gao, J, Wriggers, H, Ekker, A, Wang, L, Thomson, J.A, Dragovich, P.S, Fuhrman, S.A.
登録日	2003-03-18
公開日	2004-03-18
最終更新日	2024-04-03
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme. J.Virol., 77, 2003

Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone
分子名称:	2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol, Heat shock protein HSP 90-alpha, PHOSPHATE ION
著者	Gajiwala, K.S.
登録日	2008-09-19
公開日	2008-11-25
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.55 Å)
主引用文献	Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone. Bioorg.Med.Chem.Lett., 18, 2008

Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone
分子名称:	4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol, Heat shock protein HSP 90-alpha, PHOSPHATE ION
著者	Gajiwala, K.S.
登録日	2008-09-19
公開日	2008-11-25
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone. Bioorg.Med.Chem.Lett., 18, 2008