6V0J
 
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 8 | | Descriptor: | Intermembrane transport protein YebT | | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | Deposit date: | 2019-11-18 | | Release date: | 2020-05-06 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6V0G
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 5 | | Descriptor: | Intermembrane transport protein YebT | | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | Deposit date: | 2019-11-18 | | Release date: | 2020-05-06 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6V0I
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 7 | | Descriptor: | Intermembrane transport protein YebT | | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | Deposit date: | 2019-11-18 | | Release date: | 2020-05-06 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6VCI
 | | Lipophilic envelope-spanning tunnel protein (LetB), domains MCE2-MCE3 | | Descriptor: | Lipophilic envelope-spanning tunnel protein LetB | | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | Deposit date: | 2019-12-21 | | Release date: | 2020-05-06 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6V0D
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 2 | | Descriptor: | Intermembrane transport protein YebT | | Authors: | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | Deposit date: | 2019-11-18 | | Release date: | 2020-05-06 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6XGY
 | | Crystal structure of E. coli MlaFB ABC transport subunits in the dimeric state | | Descriptor: | ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Chang, Y, Bhabha, G, Ekiert, D.C. | | Deposit date: | 2020-06-18 | | Release date: | 2020-07-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation.
Elife, 9, 2020
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6XBD
 | | Cryo-EM structure of MlaFEDB in nanodiscs with phospholipid substrates | | Descriptor: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, MSP1D1, Phospholipid ABC transporter permease protein MlaE, ... | | Authors: | Coudray, N, Isom, G.L, MacRae, M.R, Saiduddin, M, Ekiert, D.C, Bhabha, G. | | Deposit date: | 2020-06-05 | | Release date: | 2020-07-01 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Structure of bacterial phospholipid transporter MlaFEDB with substrate bound.
Elife, 9, 2020
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6XGZ
 | | Crystal structure of E. coli MlaFB ABC transport subunits in the monomeric state | | Descriptor: | 1,2-ETHANEDIOL, ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ... | | Authors: | Chang, Y, Bhabha, G, Ekiert, D.C. | | Deposit date: | 2020-06-18 | | Release date: | 2020-07-15 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation.
Elife, 9, 2020
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5CWF
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5CWQ
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5CWJ
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5CWP
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5CWL
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5CWH
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5CWO
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5CWC
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5CWM
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5CWN
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5CWB
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5CWK
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5CWG
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5CWI
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5CWD
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4M6L
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and 5,10-dideazatetrahydrofolic acid | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydrofolate reductase, N-(4-{2-[(6S)-2-amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl]ethyl}benzoyl)-L-glutamic acid, ... | | Authors: | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | Deposit date: | 2013-08-09 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
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4M6J
 | | Crystal structure of human dihydrofolate reductase (DHFR) bound to NADPH | | Descriptor: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A. | | Deposit date: | 2013-08-09 | | Release date: | 2013-09-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.201 Å) | | Cite: | Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
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