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Solution NMR structure of transmembrane domain of amyloid precursor protein WT
Descriptor:	Amyloid beta A4 protein
Authors:	Chen, W, Wang, C.
Deposit date:	2012-09-23
Release date:	2013-10-02
Last modified:	2024-05-01
Method:	SOLUTION NMR
Cite:	Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site. Nat Commun, 5, 2014

Solution NMR structure of transmembrane domain of amyloid precursor protein V44M
Descriptor:	Amyloid beta A4 protein
Authors:	Chen, W, Wang, C.
Deposit date:	2012-09-23
Release date:	2013-10-02
Last modified:	2024-05-15
Method:	SOLUTION NMR
Cite:	Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site. Nat Commun, 5, 2014

Characterization of Peptide Ligands Against WDR5 Isolated Using Phage Display Technique
Descriptor:	CYS-ARG-THR-LEU-PRO-PHE, WD repeat-containing protein 5
Authors:	Cao, J, Cao, D, Xiong, B, Li, Y, Fan, T.
Deposit date:	2020-12-10
Release date:	2021-02-10
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.03 Å)
Cite:	Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5. Molecules, 26, 2021

NSD2-PWWP1 domain bound with an imidazol-5-yl benzonitrile compound
Descriptor:	4-[5-[4-(aminomethyl)-2,6-dimethoxy-phenyl]-3-methyl-imidazol-4-yl]benzenecarbonitrile, Histone-lysine N-methyltransferase NSD2
Authors:	Cao, D.Y, Li, Y.L, Li, J, Xiong, B.
Deposit date:	2021-10-05
Release date:	2022-07-06
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (3.09 Å)
Cite:	Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors. J.Med.Chem., 65, 2022