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1CEO
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BU of 1ceo by Molmil
CELLULASE (CELC) MUTANT WITH GLU 140 REPLACED BY GLN
Descriptor: CELLULASE CELC
Authors:Dominguez, R, Alzari, P.M.
Deposit date:1995-12-04
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
J.Mol.Biol., 257, 1996
1CEN
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BU of 1cen by Molmil
CELLULASE (CELC) MUTANT WITH GLU 140 REPLACED BY GLN COMPLEXED WITH CELLOHEXAOSE
Descriptor: CELLULASE CELC, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Dominguez, R, Alzari, P.M.
Deposit date:1995-12-04
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
J.Mol.Biol., 257, 1996
1BR4
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BU of 1br4 by Molmil
SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.BEF3 BOUND AT THE ACTIVE SITE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Dominguez, R, Trybus, K.M, Cohen, C.
Deposit date:1998-08-27
Release date:1998-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
Cell(Cambridge,Mass.), 94, 1998
1BR2
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BU of 1br2 by Molmil
SMOOTH MUSCLE MYOSIN MOTOR DOMAIN COMPLEXED WITH MGADP.ALF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ...
Authors:Dominguez, R, Trybus, K.M, Cohen, C.
Deposit date:1998-08-26
Release date:1998-09-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
Cell(Cambridge,Mass.), 94, 1998
1BR1
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BU of 1br1 by Molmil
SMOOTH MUSCLE MYOSIN MOTOR DOMAIN-ESSENTIAL LIGHT CHAIN COMPLEX WITH MGADP.ALF4 BOUND AT THE ACTIVE SITE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MYOSIN, ...
Authors:Dominguez, R, Trybus, K.M, Cohen, C.
Deposit date:1998-08-26
Release date:1998-09-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
Cell(Cambridge,Mass.), 94, 1998
1CEC
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BU of 1cec by Molmil
A COMMON PROTEIN FOLD AND SIMILAR ACTIVE SITE IN TWO DISTINCT FAMILIES OF BETA-GLYCANASES
Descriptor: ENDOGLUCANASE CELC
Authors:Alzari, P.M, Dominguez, R.
Deposit date:1995-06-07
Release date:1996-01-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A common protein fold and similar active site in two distinct families of beta-glycanases.
Nat.Struct.Biol., 2, 1995
6PSD
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BU of 6psd by Molmil
Complex of CRACR2a with a Dynein Light Intermediate Chain Peptide
Descriptor: CALCIUM ION, EF-hand calcium-binding domain-containing protein 4B, cDNA FLJ10219 fis, ...
Authors:Dominguez, R, Lee, I.G.
Deposit date:2019-07-12
Release date:2020-07-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner.
Nat Commun, 11, 2020
6PSE
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BU of 6pse by Molmil
Complex of BICD2 with a Dynein Light Intermediate Chain Peptide
Descriptor: Cytoplasmic dynein 1 light intermediate chain 1, Protein bicaudal D homolog 2
Authors:Dominguez, R, Lee, I.G.
Deposit date:2019-07-12
Release date:2020-07-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner.
Nat Commun, 11, 2020
1XYZ
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BU of 1xyz by Molmil
A COMMON PROTEIN FOLD AND SIMILAR ACTIVE SITE IN TWO DISTINCT FAMILIES OF BETA-GLYCANASES
Descriptor: 1,4-BETA-D-XYLAN-XYLANOHYDROLASE
Authors:Alzari, P.M, Spinelli, S, Dominguez, R.
Deposit date:1995-06-07
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A common protein fold and similar active site in two distinct families of beta-glycanases.
Nat.Struct.Biol., 2, 1995
2R0O
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BU of 2r0o by Molmil
Crystal structure of the actin-binding domain of human alpha-actinin-4 mutant(K255E)
Descriptor: Alpha-actinin-4, GLYCEROL
Authors:Lee, S.H, Dominguez, R.
Deposit date:2007-08-20
Release date:2008-02-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis.
J.Mol.Biol., 376, 2008
9DLX
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BU of 9dlx by Molmil
Bovine Arp2/3 complex with N-WASP CA bound to Arp3 and Arp2-ArpC1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin nucleation-promoting factor WASL, Actin-related protein 2, ...
Authors:Saks, A.J, Barrie, K.R, Dominguez, R.
Deposit date:2024-09-11
Release date:2025-02-12
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Arp 2/3 complex with bound NPFs
To Be Published
9DLZ
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BU of 9dlz by Molmil
Bovine Arp2/3 complex with N-WASP CA bound to Arp3
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ...
Authors:Saks, A.J, Barrie, K.R, Dominguez, R.
Deposit date:2024-09-11
Release date:2025-02-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Arp 2/3 complex with bound NPFs
To Be Published
5V7X
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BU of 5v7x by Molmil
Crystal Structure of Myosin 1b residues 1-728 with bound sulfate and Calmodulin
Descriptor: Calmodulin-1, SULFATE ION, Unconventional myosin-Ib
Authors:Zwolak, A, Shuman, H, Dominguez, R, Ostap, E.M.
Deposit date:2017-03-20
Release date:2018-02-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.141 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8VIZ
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BU of 8viz by Molmil
Structure of full-length gelsolin bound to the barbed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Barrie, K.R, Rebowski, G, Dominguez, R.
Deposit date:2024-01-05
Release date:2024-10-16
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Mechanism of actin filament severing and capping by gelsolin.
Nat.Struct.Mol.Biol., 32, 2025
8VKH
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BU of 8vkh by Molmil
Structure of gelsolin domains G1G3 bound to the barbed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Barrie, K.R, Rebowski, G, Dominguez, R.
Deposit date:2024-01-09
Release date:2024-10-16
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Mechanism of actin filament severing and capping by gelsolin.
Nat.Struct.Mol.Biol., 32, 2025
5WFN
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BU of 5wfn by Molmil
Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT)
Descriptor: Actin-5C, Leiomodin-2, MAGNESIUM ION, ...
Authors:Yurtsever, Z, Eck, M.J, Dominguez, R.
Deposit date:2017-07-12
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
7JPN
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BU of 7jpn by Molmil
Cryo-EM structure of Arpin-bound Arp2/3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G.
Deposit date:2020-08-09
Release date:2022-02-09
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:Molecular mechanism of Arp2/3 complex inhibition by Arpin.
Nat Commun, 13, 2022
9E2P
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BU of 9e2p by Molmil
Complex of Human MIRO1 and TRAK1 Binding Site-2 (L570-R613)
Descriptor: CALCIUM ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ravitch, E.E, Baltrusaitis, E.E, Barrie, K.R, Dominguez, R.
Deposit date:2024-10-22
Release date:2025-07-09
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Complex of Human MIRO1 and TRAK1 Binding Site-2 (L570-R613)
To Be Published
2TN4
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BU of 2tn4 by Molmil
FOUR CALCIUM TNC
Descriptor: CALCIUM ION, TROPONIN C
Authors:Love, M.L, Dominguez, R, Houdusse, A, Cohen, C.
Deposit date:1997-09-18
Release date:1998-04-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily.
Structure, 5, 1997
6NAS
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BU of 6nas by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-06
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NBW
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BU of 6nbw by Molmil
Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-10
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NBE
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BU of 6nbe by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-07
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
9AZQ
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BU of 9azq by Molmil
INF2 at the Barbed End of F-Actin with Incoming Actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Palmer, N.J, Barrie, K.R, Dominguez, R.
Deposit date:2024-03-11
Release date:2024-05-29
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Mechanisms of actin filament severing and elongation by formins.
Nature, 632, 2024
9AZ4
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BU of 9az4 by Molmil
INF2 at the Barbed End of F-Actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Palmer, N.J, Barrie, K.R, Dominguez, R.
Deposit date:2024-03-10
Release date:2024-05-29
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Mechanisms of actin filament severing and elongation by formins.
Nature, 632, 2024
9AZP
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BU of 9azp by Molmil
INF2 at the Barbed End of F-Actin with Incoming Profilin-Actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Palmer, N.J, Barrie, K.R, Dominguez, R.
Deposit date:2024-03-11
Release date:2024-05-29
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Mechanisms of actin filament severing and elongation by formins.
Nature, 632, 2024

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