9QE5
 
 | | VCB in complex with VHL-binding compound 82 | | Descriptor: | (2~{S},4~{R})-1-[(2~{S})-1-(1-fluoranylcyclopropyl)carbonylpiperidin-2-yl]carbonyl-~{N}-[(1~{S})-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | Authors: | Braun, M.B, Dierlamm, N, Hartmann, M.D. | | Deposit date: | 2025-03-07 | | Release date: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Breaking Barriers in PROTAC Design: Improving Solubility of USP7-Targeting Degraders
To Be Published
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9QE4
 | | VCB in complex with VHL-binding compound 114 | | Descriptor: | (2~{S},4~{R})-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-~{N}-[(1~{S})-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | Authors: | Braun, M.B, Dierlamm, N, Hartmann, M.D. | | Deposit date: | 2025-03-07 | | Release date: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Breaking Barriers in PROTAC Design: Improving Solubility of USP7-Targeting Degraders
To Be Published
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