2AAQ
| Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI | Descriptor: | 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Urig, S, Fritz-Wolf, K, Reau, R, Herold-Mende, C, Toth, K, Davioud-Charvet, E, Becker, K. | Deposit date: | 2005-07-14 | Release date: | 2006-04-04 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Undressing of Phosphine Gold(I) Complexes as Irreversible Inhibitors of Human Disulfide Reductases. Angew.Chem.Int.Ed.Engl., 45, 2006
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2GH5
| Crystal Structure of human Glutathione Reductase complexed with a Fluoro-Analogue of the Menadione Derivative M5 | Descriptor: | 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | Authors: | Fritz-Wolf, K, Winzer, A, Bauer, H, Schirmer, H, Davioud-Charvet, E. | Deposit date: | 2006-03-25 | Release date: | 2006-09-26 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme J.Am.Chem.Soc., 128, 2006
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