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8UWF
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BU of 8uwf by Molmil
NMR structure of the funnel-web spider toxin Hc3a
分子名称: Pi-Hexatoxin-Hc1b_1
著者Budusan, E, Payne, C.D, Gonzalez, T.I, Clark, R.J, Rosengren, K.J, Rash, L.D, Cristofori-Armstrong, B.
登録日2023-11-06
公開日2024-03-13
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation.
Biochem Pharmacol, 2024
8EQS
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BU of 8eqs by Molmil
Structure of SARS-CoV-1 Orf3a in late endosome/lysosome-like environment, MSP1D1 nanodisc
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apolipoprotein A-I, ORF3a protein
著者Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
登録日2022-10-09
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
8EQJ
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Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like membrane environment, MSP1D1 nanodisc
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein
著者Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
登録日2022-10-07
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
8EQT
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Structure of SARS-CoV-2 Orf3a in plasma membrane-like environment, MSP1D1 nanodisc
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein
著者Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
登録日2022-10-09
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
8EQU
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Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein, Saposin A, ...
著者Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E.
登録日2022-10-09
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
6A90
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BU of 6a90 by Molmil
Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana and Dc1a
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mu-diguetoxin-Dc1a, ...
著者Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
登録日2018-07-11
公開日2018-08-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A91
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Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with saxitoxin and Dc1a
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
登録日2018-07-11
公開日2018-08-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A95
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Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with tetrodotoxin and Dc1a
分子名称: (1R,5R,6R,7R,9S,11S,12S,13S,14S)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shen, H.Z, li, Z.Q, Jiang, Y, Pan, X.J, Wu, J.P, Cristofori-Armstrong, B, Smith, J.J, Chin, Y.K.Y, Lei, J.L, Zhou, Q, King, G.F, Yan, N.
登録日2018-07-11
公開日2018-08-08
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
2MUB
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BU of 2mub by Molmil
Solution structure of the analgesic sea anemone peptide APETx2
分子名称: Toxin APETx2
著者Mobli, M, King, G.F, Rosengren, K.J, Jensen, J.E.
登録日2014-09-07
公開日2014-12-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores.
J.Med.Chem., 57, 2014
5I2P
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BU of 5i2p by Molmil
Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a (W6A in native sequence numbering)
分子名称: W7A mu-TRTX-Pre1a Toxin
著者Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D.
登録日2016-02-09
公開日2017-06-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a
To Be Published
6CUC
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BU of 6cuc by Molmil
Solution structure of double knot toxin (DkTx)
分子名称: Tau-theraphotoxin-Hs1a
著者Ramanujam, V, Mobli, M.
登録日2018-03-25
公開日2019-03-27
最終更新日2024-04-24
実験手法SOLUTION NMR
主引用文献Structural Basis of the Bivalency of the TRPV1 Agonist DkTx.
Angew.Chem.Int.Ed.Engl., 63, 2024
6AZA
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BU of 6aza by Molmil
NMR structure of sea anemone toxin Kappa-actitoxin-Ate1a
分子名称: ARG-CYS-LYS-THR-CYS-SER-LYS-GLY-ARG-CYS-ARG-PRO-LYS-PRO-ASN-CYS-GLY-NH2
著者Chin, Y.K.-Y, Madio, B, King, G.F, Undheim, E.A.B.
登録日2017-09-10
公開日2018-09-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold.
Cell. Mol. Life Sci., 75, 2018
7JPM
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BU of 7jpm by Molmil
The solution structure of omega-theraphotoxin-Pm1b isolated from King Baboon spider
分子名称: Omega-theraphotoxin-Pm1b
著者Chin, Y.K.-Y, Ziegman, R, Alewood, P.F.
登録日2020-08-09
公開日2021-09-08
最終更新日2023-10-11
実験手法SOLUTION NMR
主引用文献Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Proc.Natl.Acad.Sci.USA, 119, 2022
7L2G
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BU of 7l2g by Molmil
NMR solution structure of Nak1 from the Necator americanus hookworm
分子名称: ShTK domain protein
著者Smallwood, T.B, Rosengren, K.J, Clark, R.J.
登録日2020-12-17
公開日2021-10-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Synthetic hookworm-derived peptides are potent modulators of primary human immune cell function that protect against experimental colitis in vivo.
J.Biol.Chem., 297, 2021

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件を2024-04-24に公開中

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