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7JHP
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BU of 7jhp by Molmil
Crystal structure of HRas in complex with the Ras-binding and cysteine-rich domains of CRaf-kinase
Descriptor: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Cookis, T, Mattos, C.
Deposit date:2020-07-21
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.766 Å)
Cite:Crystal Structure Reveals the Full Ras-Raf Interface and Advances Mechanistic Understanding of Raf Activation.
Biomolecules, 11, 2021
8VMI
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BU of 8vmi by Molmil
PRC2_AJ119-450 bound to H3K4me3
Descriptor: EZH2, Histone H3.1, Histone H3.1t, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-13
Release date:2025-01-15
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8VMJ
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BU of 8vmj by Molmil
H3K4me3 nucleosome bound to PRC2_AJ119-450
Descriptor: DNA (157-MER), Histone H2A, Histone H2B, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-13
Release date:2025-01-15
Last modified:2025-03-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8VML
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BU of 8vml by Molmil
PRC2_AJ1-450 bound to H3K4me3
Descriptor: AEPB2, EED, EZH2, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-13
Release date:2025-01-15
Last modified:2025-03-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8VOB
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BU of 8vob by Molmil
H3K36me3-modified nucleosome bound to PRC2_AJ1-450
Descriptor: DNA (157-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-14
Release date:2025-01-15
Last modified:2025-03-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8VMN
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BU of 8vmn by Molmil
H3K4me3 nucleosome bound to PRC2_AJ1-450
Descriptor: DNA (157-MER), Histone H2A, Histone H2B, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-13
Release date:2025-01-22
Last modified:2025-03-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8VNZ
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BU of 8vnz by Molmil
PRC2_AJ1-450 bound to H3K36me3-modified nucleosome with histone H3 tail disengaged
Descriptor: Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, Isoform 3 of Zinc finger protein AEBP2, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-14
Release date:2025-01-15
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8VO0
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BU of 8vo0 by Molmil
H3K36me3-modified nucleosome bound to PRC2_AJ1-450 with histone H3 tail disengaged
Descriptor: DNA (157-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-14
Release date:2025-01-22
Last modified:2025-03-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8VNV
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BU of 8vnv by Molmil
PRC2_AJ1-450 bound to H3K36me3 with histone H3 tail engaged
Descriptor: DNA (26-MER), DNA (26-mer), EED, ...
Authors:Cookis, T, Nogales, E.
Deposit date:2024-01-13
Release date:2025-01-22
Last modified:2025-03-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications.
Nat.Struct.Mol.Biol., 32, 2025
8TB9
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BU of 8tb9 by Molmil
PRC2-J119-450 monomer bound to H1-nucleosome
Descriptor: DNA (226-MER), Histone H1.0, Histone H2A type 1, ...
Authors:Sauer, P.V, Cookis, T, Pavlenko, E, Nogales, E, Poepsel, S.
Deposit date:2023-06-28
Release date:2024-09-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Activation of automethylated PRC2 by dimerization on chromatin.
Mol.Cell, 84, 2024
8TAS
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BU of 8tas by Molmil
PRC2 monomer bound to nucleosome
Descriptor: DNA (226-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Sauer, P.V, Pavlenko, E, Nogales, E, Poepsel, S.
Deposit date:2023-06-27
Release date:2024-09-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Activation of automethylated PRC2 by dimerization on chromatin.
Mol.Cell, 84, 2024
8T9G
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BU of 8t9g by Molmil
Automethylated PRC2 dimer bound to nucleosome
Descriptor: DNA (226-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Sauer, P.V, Pavlenko, E, Nogales, E, Poepsel, S.
Deposit date:2023-06-23
Release date:2024-09-25
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Activation of automethylated PRC2 by dimerization on chromatin.
Mol.Cell, 84, 2024

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PDB entries from 2025-12-31

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