9MLY
 
 | | Azotobacter vinelandii Reduced MoFeP (C1 symmetry) obtained using the SPT Labtech chameleon of 5 mM sodium dithionite under Al's oil | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-12-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.33 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9MM0
 | | Azotobacter vinelandii Reduced MoFeP (C1 symmetry) obtained using the SPT Labtech chameleon of 60 mM sodium dithionite under Al's oil | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-12-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.19 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9MM1
 | | Azotobacter vinelandii Reduced MoFeP (C2 symmetry) obtained using the SPT Labtech chameleon of 60 mM sodium dithionite under Al's oil | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-12-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.08 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9MLZ
 | | Azotobacter vinelandii Reduced MoFeP (C2 symmetry) obtained using the SPT Labtech chameleon of 5 mM sodium dithionite under Al's oil | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-12-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.19 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQN
 | | Human OxyHb (C2 symmetry) obtained using the SPT Labtech chameleon In the presence of 25 uM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.37 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQX
 | | Azotobacter vinelandii Oxidized MoFeP (C1 symmetry) obtained using the SPT Labtech chameleon | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQY
 | | Azotobacter vinelandii Oxidized MoFeP (C2 symmetry) obtained using the SPT Labtech chameleon | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.39 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQV
 | | Human DeoxyHb (C1 symmetry) obtained using the SPT Labtech chameleon In the presence of 60 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQR
 | | Human metHb (C2 symmetry) obtained using the SPT Labtech chameleon under Al's Oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQZ
 | | Azotobacter vinelandii Reduced MoFeP (C1 symmetry) obtained using the SPT Labtech chameleon of 20 mM sodium dithionite under Al's oil | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.19 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQT
 | | Human OxyHb (C2 symmetry) obtained using the SPT Labtech chameleon In the presence of 5 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.37 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQP
 | | Human metHb (C2 symmetry) obtained using the SPT Labtech chameleon | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQW
 | | Human DeoxyHb (C2 symmetry) obtained using the SPT Labtech chameleon In the presence of 60 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQO
 | | Human metHb (C1 symmetry) obtained using the SPT Labtech chameleon | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CR0
 | | Azotobacter vinelandii Reduced MoFeP (C2 symmetry) obtained using the SPT Labtech chameleon of 20 mM sodium dithionite under Al's oil | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.08 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQQ
 | | Human metHb (C1 symmetry) obtained using the SPT Labtech chameleon under Al's Oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.91 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQS
 | | Human OxyHb (C1 symmetry) obtained using the SPT Labtech chameleon In the presence of 5 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQU
 | | Human OxyHb (C1 symmetry) obtained using the SPT Labtech chameleon In the presence of 20 mM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9CQM
 | | Human OxyHb (C1 symmetry) obtained using the SPT Labtech chameleon In the presence of 25 uM sodium dithionite under Al's oil | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | | Authors: | Cook, B.D, Narehood, S.M, McGuire, K.L, Li, Y, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2024-07-19 | | Release date: | 2025-04-30 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using blot-free vitrification.
Nat Commun, 16, 2025
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9PKQ
 | | Structure of the cytoplasmic domain of unliganded human Tom70, open and closed conformations | | Descriptor: | Mitochondrial import receptor subunit TOM70 | | Authors: | Bachochin, M.J, McGuire, K.L, Cook, B.D, Ye, Q, Silletti, S, Corbett, K.D, Komives, E.A, Herzik Jr, M.A. | | Deposit date: | 2025-07-14 | | Release date: | 2026-03-18 | | Last modified: | 2026-03-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | An allosteric network governs Tom70 conformational dynamics to coordinate mitochondrial import.
Structure, 34, 2026
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7UTA
 | | CryoEM structure of Azotobacter vinelandii nitrogenase complex (2:1 FeP:MoFeP) inhibited by BeFx during catalytic N2 reduction | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM, ... | | Authors: | Rutledge, H.L, Cook, B.D, Nguyen, H.P.M, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2022-04-26 | | Release date: | 2022-08-17 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions.
Science, 377, 2022
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7UT7
 | | C2 symmetric cryoEM structure of Azotobacter vinelandii MoFeP under non-turnover conditions | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | | Authors: | Rutledge, H.L, Cook, B.D, Tezcan, F.A, Herzik, M.A. | | Deposit date: | 2022-04-26 | | Release date: | 2022-08-17 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (1.91 Å) | | Cite: | Structures of the nitrogenase complex prepared under catalytic turnover conditions.
Science, 377, 2022
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9CU2
 | | Azotobacter vinelandii filamentous 2:2:1 MoFeP:FeP:FeSII-Complex (C2 symmetry) | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | | Authors: | Narehood, S.M, Cook, B.D, Srisantitham, S, Eng, V.H, Shiau, A, Britt, R.D, Herzik, M.A, Tezcan, F.A. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-15 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.27 Å) | | Cite: | Structural basis for the conformational protection of nitrogenase from O 2 .
Nature, 637, 2025
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9CU1
 | | Azotobacter vinelandii filamentous 2:2:1 MoFeP:FeP:FeSII-Complex (termini; C1 symmetry) | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | | Authors: | Narehood, S.M, Cook, B.D, Srisantitham, S, Eng, V.H, Shiau, A, Britt, R.D, Herzik, M.A, Tezcan, F.A. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-15 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Structural basis for the conformational protection of nitrogenase from O 2 .
Nature, 637, 2025
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9CU0
 | | Azotobacter vinelandii 1:1:1 MoFeP:FeP:FeSII-Complex (C1 symmetry) | | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | | Authors: | Narehood, S.M, Cook, B.D, Srisantitham, S, Eng, V.H, Shiau, A, Britt, R.D, Herzik, M.A, Tezcan, F.A. | | Deposit date: | 2024-07-25 | | Release date: | 2025-01-15 | | Last modified: | 2025-08-20 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Structural basis for the conformational protection of nitrogenase from O 2 .
Nature, 637, 2025
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