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5D1N
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BU of 5d1n by Molmil
Crystal structure of the 16S rRNA (adenine(1408)-N(1))-methyltransferase with its reaction by-product SAH from Catenulisporales acidiphilia
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, Uncharacterized protein
Authors:Witek, M.A, Conn, G.L.
Deposit date:2015-08-04
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.713 Å)
Cite:Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization.
Nucleic Acids Res., 44, 2016
5EOV
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BU of 5eov by Molmil
C-terminal domain of the 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA.
Descriptor: 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA
Authors:Witek, M.A, Conn, G.L.
Deposit date:2015-11-10
Release date:2016-11-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis.
J. Biol. Chem., 292, 2017
4OX9
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BU of 4ox9 by Molmil
Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit
Descriptor: 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ...
Authors:Dunkle, J.A, Conn, G.L, Dunham, C.M.
Deposit date:2014-02-04
Release date:2014-04-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.8035 Å)
Cite:Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
404D
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BU of 404d by Molmil
CRYSTAL STRUCTURE OF THE RNA/DNA HYBRID R(GAAGAGAAGC). D(GCTTCTCTTC)
Descriptor: 5'-D(*GP*CP*TP*TP*CP*TP*CP*TP*TP*C)-3', 5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3'
Authors:Conn, G, Brown, T, Leonard, G.A.
Deposit date:1998-06-12
Release date:1998-12-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution.
Nucleic Acids Res., 27, 1999
4RWZ
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BU of 4rwz by Molmil
Crystal structure of the antibiotic-resistance methyltransferase Kmr
Descriptor: Putative rRNA methyltransferase
Authors:Savic, M.
Deposit date:2014-12-08
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:30S Subunit-Dependent Activation of the Sorangium cellulosum So ce56 Aminoglycoside Resistance-Conferring 16S rRNA Methyltransferase Kmr.
Antimicrob.Agents Chemother., 59, 2015
4RX1
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BU of 4rx1 by Molmil
Crystal Structure of antibiotic-resistance methyltransferase Kmr
Descriptor: GLYCEROL, IODIDE ION, Putative rRNA methyltransferase
Authors:Savic, M.
Deposit date:2014-12-08
Release date:2015-03-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.472 Å)
Cite:30S Subunit-Dependent Activation of the Sorangium cellulosum So ce56 Aminoglycoside Resistance-Conferring 16S rRNA Methyltransferase Kmr.
Antimicrob.Agents Chemother., 59, 2015
3PYJ
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BU of 3pyj by Molmil
Reduced sweetness of a monellin (MNEI) mutant results from increased protein flexibility and disruption of a distant poly-(L-proline) II helix
Descriptor: FORMIC ACID, Monellin chain B/Monellin chain A chimeric protein
Authors:Hobbs, J.R, Conn, G.C, Munger, S.D, Templeton, C.M.
Deposit date:2010-12-13
Release date:2011-04-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix.
Chem Senses, 36, 2011
3MQ2
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BU of 3mq2 by Molmil
Crystal Structure of 16S rRNA Methyltranferase KamB
Descriptor: 16S rRNA methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Macmaster, R.A.
Deposit date:2010-04-27
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria.
Nucleic Acids Res., 38, 2010
4MCE
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BU of 4mce by Molmil
Crystal structure of the Gas5 GRE Mimic
Descriptor: Gas5 GREM Fwd, Gas5 GREM Rev, SULFATE ION
Authors:Hudson, W.H, Ortlund, E.A.
Deposit date:2013-08-21
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate.
Nat Commun, 5, 2014
4MCF
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BU of 4mcf by Molmil
Crystal structure of the Gas5 GRE Mimic
Descriptor: Gas5 GREM Fwd, Gas5 GREM Rev, SULFATE ION
Authors:Hudson, W.H, Ortlund, E.A.
Deposit date:2013-08-21
Release date:2014-11-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate.
Nat Commun, 5, 2014
1OLN
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BU of 1oln by Molmil
Model for thiostrepton antibiotic binding to L11 substrate from 50S ribosomal RNA
Descriptor: 50S RIBOSOMAL PROTEIN L11, RNA, THIOSTREPTON
Authors:Lentzen, G, Klinck, R, Matassova, N, Aboul-Ela, F, Murchie, A.I.H.
Deposit date:2003-08-08
Release date:2003-09-11
Last modified:2019-08-21
Method:SOLUTION NMR, THEORETICAL MODEL
Cite:Structural Basis for Contrasting Activities of Ribosome Binding Thiazole Antibiotics
Chem.Biol., 10, 2003
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