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Crystal structure of CD38 with a novel CD38-targeting antibody SAR650984
Descriptor:	ADP-RIBOSYL CYCLASE 1, HEAVY CHAIN OF SAR650984-FAB FRAGMENT, LIGHT CHAIN OF SAR650984-FAB FRAGMENT
Authors:	Deckert, J, Wetzel, M.C, Park, P.U, Bartle, L.M, Skaletskaya, A, Goldmacher, V, Vallee, F, ZhouLiu, Q, Ferrari, P, Pouzieux, S, Lahoute, C, Dumontet, C, Plesa, A, Chiron, M, Lejeune, P, Chittenden, T, Blanc, V.
Deposit date:	2014-01-15
Release date:	2014-07-16
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (1.53 Å)
Cite:	SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies. Clin. Cancer Res., 20, 2014

Anti-CD28xCD3 CODV Fab bound to CD28
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-CD28xCD3 CODV Fab Heavy chain, ...
Authors:	Lord, D.M, Wei, R.R.
Deposit date:	2019-03-09
Release date:	2019-11-20
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (3.547 Å)
Cite:	Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation To Be Published

Anti-CD28xCD3 CODV Fab
Descriptor:	Anti-CD28xCD3 CODV-Fab Heavy chain, Anti-CD28xCD3 CODV-Fab Light chain
Authors:	Lord, D.M, Wei, R.R.
Deposit date:	2019-03-09
Release date:	2019-11-20
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.09 Å)
Cite:	Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation Nat Cancer, 1, 2020