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monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-CL interface
Descriptor:	Fab Lambda light chain, IgG1 Fab heavy chain
Authors:	Oganesyan, V.Y, van Dyk, N, Mazor, Y, Chiang, C.
Deposit date:	2023-07-21
Release date:	2023-11-22
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the C H 1-C lambda interface. Mabs, 15, 2023

Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZL0590
Descriptor:	Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, N-[4-({(2S)-2-[(morpholin-4-yl)methyl]pyrrolidin-1-yl}sulfonyl)phenyl]-N'-[4-(trifluoromethyl)phenyl]urea
Authors:	Leonard, P.G, Joseph, S.
Deposit date:	2019-08-14
Release date:	2020-08-19
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.43 Å)
Cite:	Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site J. Med. Chem., 2022