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4MHG
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BU of 4mhg by Molmil
Crystal structure of ETV6 bound to a specific DNA sequence
Descriptor: Complementary Specific 14 bp DNA, Specific 14 bp DNA, Transcription factor ETV6
Authors:Chan, A.C, De, S, Coyne III, H.J, Okon, M, Murphy, M.E, Graves, B.J, McIntosh, L.P.
Deposit date:2013-08-29
Release date:2014-01-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
5DPT
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BU of 5dpt by Molmil
Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Pleckstrin homology domain-containing family M member 1, Gamma-aminobutyric acid receptor-associated protein-like 1,Gamma-aminobutyric acid receptor-associated protein-like 1
Authors:Ravichandran, A.C, Suzuki, H, Dobson, R.C.J.
Deposit date:2015-09-14
Release date:2016-09-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional analysis of the GABARAP interaction motif (GIM).
EMBO Rep., 18, 2017
5DPW
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BU of 5dpw by Molmil
Crystal structure of PLEKHM1 LIR in complex with human LC3C_8-125
Descriptor: Microtubule-associated proteins 1A/1B light chain 3C, Pleckstrin homology domain-containing family M member 1
Authors:Ravichandran, A.C, Suzuki, H, Dobson, R.C.J.
Deposit date:2015-09-14
Release date:2016-09-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.185 Å)
Cite:Structural and functional analysis of the GABARAP interaction motif (GIM).
EMBO Rep., 18, 2017
5DPR
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BU of 5dpr by Molmil
Crystal structure of PLEKHM1 LIR-fused human LC3A_2-121
Descriptor: Pleckstrin homology domain-containing family M member 1,Microtubule-associated proteins 1A/1B light chain 3A
Authors:Ravichandran, A.C, Suzuki, H, Dobson, R.C.J.
Deposit date:2015-09-14
Release date:2016-09-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional analysis of the GABARAP interaction motif (GIM).
EMBO Rep., 18, 2017
5DPS
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BU of 5dps by Molmil
Crystal structure of PLEKHM1 LIR-fused human GABARAP_2-117
Descriptor: Pleckstrin homology domain-containing family M member 1,Gamma-aminobutyric acid receptor-associated protein
Authors:Ravichandran, A.C, Suzuki, H, Dobson, R.C.J.
Deposit date:2015-09-14
Release date:2016-09-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the GABARAP interaction motif (GIM).
EMBO Rep., 18, 2017
5VMM
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BU of 5vmm by Molmil
Staphylococcus aureus IsdB bound to human hemoglobin
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated cell wall-anchored protein, ...
Authors:Bowden, C.F, Chan, A.C, Murphy, M.E.
Deposit date:2017-04-27
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin.
J. Biol. Chem., 293, 2018
5VN5
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BU of 5vn5 by Molmil
Crystal structure of LigY from Sphingobium sp. strain SYK-6
Descriptor: 2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl meta-cleavage compound hydrolase, CHLORIDE ION, ZINC ION
Authors:Kuatsjah, E, Chan, A.C.K, Kobylarz, M.J, Murphy, M.E.P, Eltis, L.D.
Deposit date:2017-04-28
Release date:2017-09-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The bacterialmeta-cleavage hydrolase LigY belongs to the amidohydrolase superfamily, not to the alpha / beta-hydrolase superfamily.
J. Biol. Chem., 292, 2017
6XJ6
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BU of 6xj6 by Molmil
Crystal structure of the helical cell shape determining protein Pgp2 from Campylobacter jejuni
Descriptor: Pgp2
Authors:Lin, C.S, Chan, A.C, Murphy, M.E.
Deposit date:2020-06-23
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni.
J.Biol.Chem., 296, 2021
6XJ7
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BU of 6xj7 by Molmil
Crystal structure of the helical cell shape determining protein Pgp2 (K307A mutant) from Campylobacter jejuni
Descriptor: Pgp2
Authors:Lin, C.S, Chan, A.C, Murphy, M.E.
Deposit date:2020-06-23
Release date:2021-03-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni.
J.Biol.Chem., 296, 2021
6XM8
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BU of 6xm8 by Molmil
Crystal structure of lignostilbene bound to Co-LSD4 from Sphingobium sp. strain SYK-6
Descriptor: COBALT (II) ION, DIMETHYL SULFOXIDE, Dioxygenase, ...
Authors:Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D.
Deposit date:2020-06-29
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
6XMA
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BU of 6xma by Molmil
Crystal structure of iron-bound LSD4 from Sphingobium sp. strain SYK-6
Descriptor: Dioxygenase, FE (III) ION, SULFATE ION
Authors:Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D.
Deposit date:2020-06-29
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
6XM9
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BU of 6xm9 by Molmil
Crystal structure of vanillin bound to Co-LSD4 from Sphingobium sp. strain SYK-6
Descriptor: 4-hydroxy-3-methoxybenzaldehyde, ACETATE ION, COBALT (II) ION, ...
Authors:Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D.
Deposit date:2020-06-29
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
6XM7
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BU of 6xm7 by Molmil
Crystal structure of DCA-S bound to Co-LSD4 from Sphingobium sp. strain SYK-6
Descriptor: (2E)-3-{4-hydroxy-3-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-5-methoxyphenyl}prop-2-enoic acid, COBALT (II) ION, DIMETHYL SULFOXIDE, ...
Authors:Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D.
Deposit date:2020-06-29
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
6XM6
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BU of 6xm6 by Molmil
Crystal structure of cobalt-bound LSD4 from Sphingobium sp. strain SYK-6
Descriptor: COBALT (II) ION, Dioxygenase
Authors:Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D.
Deposit date:2020-06-29
Release date:2021-05-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
6E6I
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BU of 6e6i by Molmil
Crystal structure of 4-methyl HOPDA bound to LigY from Sphingobium sp. strain SYK-6
Descriptor: (1Z,3E)-5-carboxy-3-methyl-5-oxo-1-phenylpenta-1,3-dien-1-olate, 2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl meta-cleavage compound hydrolase, ZINC ION
Authors:Kuatsjah, E, Chan, A.C, Hurst, T.E, Snieckus, V, Murphy, M.E, Eltis, L.D.
Deposit date:2018-07-24
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal- and Serine-Dependent Meta-Cleavage Product Hydrolases Utilize Similar Nucleophile-Activation Strategies
Acs Catalysis, 8, 2018
8E67
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BU of 8e67 by Molmil
ETV6 H396Y variant bound to DNA containing the sequence GGAT
Descriptor: Complementary 15 bp strand, GGAT-containing 15 bp DNA, Transcription factor ETV6
Authors:Scheu, K, Chan, A.C, Murphy, M.E, McIntosh, L.P.
Deposit date:2022-08-22
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The functional role of histidine within the ETV6 ETS domain
to be published
8E66
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BU of 8e66 by Molmil
ETV6 H396Y variant bound to DNA containing the sequence GGAA
Descriptor: CACODYLATE ION, Complementary 15 bp strand, GGAA-containing 15 bp DNA, ...
Authors:Scheu, K, Chan, A.C, Murphy, M.E, McIntosh, L.P.
Deposit date:2022-08-22
Release date:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The functional role of histidine within the ETV6 ETS domain
to be published
2MD5
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BU of 2md5 by Molmil
Structure of uninhibited ETV6 ETS domain
Descriptor: Transcription factor ETV6
Authors:De, S, Mcintosh, L.P, Chan, A.C, Coyne, H.J, Okon, M, Graves, B.J, Murphy, M.E.
Deposit date:2013-08-29
Release date:2013-12-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
8GLD
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BU of 8gld by Molmil
Crystal structure of the peptidoglycan O-acetylesterase Ape1 (amino acids 22-392) from Campylobacter jejuni
Descriptor: ACETATE ION, SGNH hydrolase-type esterase domain-containing protein
Authors:Lin, C.S, Murphy, M.E.
Deposit date:2023-03-22
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of the CBM35 domain in assisting catalysis by Ape1, a Campylobacter jejuni O-acetyl esterase
To be published
8GKD
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BU of 8gkd by Molmil
Crystal structure of the peptidoglycan O-acetylesterase Ape1 (amino acids 41-392) from Campylobacter jejuni
Descriptor: ACETATE ION, SGNH hydrolase-type esterase domain-containing protein
Authors:Lin, C.S, Murphy, M.E.
Deposit date:2023-03-17
Release date:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of the CBM35 domain in assisting catalysis by Ape1, a Campylobacter jejuni O-acetyl esterase
To be published
4WAA
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BU of 4waa by Molmil
Crystal structure of Nix LIR-fused human LC3B_2-119
Descriptor: Microtubule-associated proteins 1A/1B light chain 3B
Authors:Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S.
Deposit date:2014-08-29
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.
Sci Rep, 7, 2017
1A81
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BU of 1a81 by Molmil
CRYSTAL STRUCTURE OF THE TANDEM SH2 DOMAIN OF THE SYK KINASE BOUND TO A DUALLY TYROSINE-PHOSPHORYLATED ITAM
Descriptor: SYK KINASE, T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN
Authors:Fuetterer, K, Waksman, G.
Deposit date:1998-03-31
Release date:1998-10-21
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.
J.Mol.Biol., 281, 1998
7Q2A
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BU of 7q2a by Molmil
Crystal structure of AphC in complex with 4-ethylcatechol
Descriptor: 4-ethylbenzene-1,2-diol, CALCIUM ION, Catechol 2,3-dioxygenase, ...
Authors:Zahn, M, Grigg, J.C, Eltis, L.D, McGeehan, J.E.
Deposit date:2021-10-25
Release date:2022-04-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds.
J.Biol.Chem., 298, 2022
1E9L
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BU of 1e9l by Molmil
The crystal structure of novel mammalian lectin Ym1 suggests a saccharide binding site
Descriptor: 2-amino-2-deoxy-beta-D-glucopyranose, YM1 SECRETORY PROTEIN
Authors:Hsiao, C.D, Sun, Y.J.
Deposit date:2000-10-21
Release date:2001-03-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Crystal Structure of a Novel Mammalian Lectin, Ym1, Suggests a Saccharide Binding Site
J.Biol.Chem., 276, 2001
5JM6
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BU of 5jm6 by Molmil
Structure of Chaetomium thermophilum mApe1
Descriptor: Aminopeptidase-like protein, ZINC ION
Authors:Bertipaglia, C, Jakobi, A.J, Wilmanns, M, Sachse, C.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle.
Embo Rep., 17, 2016

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