1ELC
 
 | | Analogous inhibitors of elastase do not always bind analogously | | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-phenylalaninamide, CALCIUM ION, ELASTASE | | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | | 登録日 | 1993-12-07 | | 公開日 | 1994-04-30 | | 最終更新日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
|
|
1EOV
 | | FREE ASPARTYL-TRNA SYNTHETASE (ASPRS) (E.C. 6.1.1.12) FROM YEAST | | 分子名称: | ASPARTYL-TRNA SYNTHETASE | | 著者 | Sauter, C, Lorber, B, Cavarelli, J, Moras, D, Giege, R. | | 登録日 | 2000-03-24 | | 公開日 | 2000-09-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain.
J.Mol.Biol., 299, 2000
|
|
1EYL
 | | STRUCTURE OF A RECOMBINANT WINGED BEAN CHYMOTRYPSIN INHIBITOR | | 分子名称: | CHYMOTRYPSIN INHIBITOR, SULFATE ION | | 著者 | Dattagupta, J.K, Chakrabarti, C, Ravichandran, S, Ghosh, S. | | 登録日 | 2000-05-07 | | 公開日 | 2000-05-24 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: crystal structures of two point mutants Asn14-->Lys and Asn14-->Asp.
Protein Eng., 14, 2001
|
|
1ERC
 | | THE NMR SOLUTION STRUCTURE OF THE PHEROMONE ER-1 FROM THE CILIATED PROTOZOAN EUPLOTES RAIKOVI | | 分子名称: | PHEROMONE ER-1 | | 著者 | Mronga, S, Luginbuhl, P, Brown, L.R, Ortenzi, C, Luporini, P, Bradshaw, R.A, Wuthrich, K. | | 登録日 | 1994-02-14 | | 公開日 | 1994-10-15 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR solution structure of the pheromone Er-1 from the ciliated protozoan Euplotes raikovi.
Protein Sci., 3, 1994
|
|
1ELB
 | | Analogous inhibitors of elastase do not always bind analogously | | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-leucinamide, CALCIUM ION, ELASTASE, ... | | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | | 登録日 | 1993-12-07 | | 公開日 | 1994-06-22 | | 最終更新日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
|
|
1EEA
 | | Acetylcholinesterase | | 分子名称: | PROTEIN (ACETYLCHOLINESTERASE) | | 著者 | Raves, M.L, Giles, K, Schrag, J.D, Schmid, M.F, Phillips Jr, G.N, Wah, C, Howard, A.J, Silman, I, Sussman, J.L. | | 登録日 | 1999-01-26 | | 公開日 | 1999-02-01 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Quaternary Structure of Tetrameric Acetylcholinesterase
Structure and Function of Cholinesterases and Related Proteins, 1998
|
|
1ELA
 | | Analogous inhibitors of elastase do not always bind analogously | | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-prolinamide, ACETIC ACID, CALCIUM ION, ... | | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | | 登録日 | 1993-12-07 | | 公開日 | 1994-04-30 | | 最終更新日 | 2012-12-12 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
|
|
4U7D
 | | Structure of human RECQ-like helicase in complex with an oligonucleotide | | 分子名称: | ATP-dependent DNA helicase Q1, DNA oligonucleotide, ZINC ION | | 著者 | Pike, A.C.W, Zhang, Y, Schnecke, C, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) | | 登録日 | 2014-07-30 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4V0S
 | | Crystal structure of Mycobacterium tuberculosis Type II Dehydroquinase D88N mutant inhibited by a 3-dehydroquinic acid derivative | | 分子名称: | (1R,2S,4S,5R)-2-(2,3,4,5,6-pentafluorophenyl)methyl-1,4,5-trihydroxy-3-oxocyclohexane-1-carboxylic acid, 3,4-DIHYDROXY-2-[(2,3,4,5,6-PENTAFLUOROPHENYL)METHYL]BENZOIC ACID, 3-DEHYDROQUINATE DEHYDRATASE, ... | | 著者 | Otero, J.M, Llamas-Saiz, A.L, Santiago, C, Lamb, H, Hawkins, A.R, Maneiro, M, Peon, A, Gonzalez-Bello, C, van Raaij, M.J. | | 登録日 | 2014-09-18 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Investigation of the Dehydratation Mechanism Catalyzed by the Type II Dehydroquinase
To be Published
|
|
4URV
 | | The crystal structure of H-Ras and SOS in complex with ligands | | 分子名称: | 4-(4-BROMOPHENYL)PIPERIDIN-4-OL, FORMIC ACID, GTPASE HRAS, ... | | 著者 | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | | 登録日 | 2014-07-02 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation.
J.Med.Chem., 58, 2015
|
|
4UU9
 | | Crystal structure of the human c5a in complex with MEDI7814 a neutralising antibody | | 分子名称: | COMPLEMENT C5, MEDI7814, SULFATE ION | | 著者 | Colley, C, Sridharan, S, Dobson, C, Popovic, B, Debreczeni, J.E, Hargreaves, D, Edwards, B, Brennan, J, England, L, Fung, S, An Eghobamien, L, Sivars, U, Woods, R, Flavell, L, Renshaw, G.J, Wickson, K, Wilkinson, T, Davies, R, Bonnell, J, Warrener, P, Howes, R, Vaughan, T. | | 登録日 | 2014-07-25 | | 公開日 | 2015-08-12 | | 最終更新日 | 2019-02-27 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
MAbs, 10, 2018
|
|
8USO
 | | Full-length human CaMKII delta holoenzyme | | 分子名称: | MALONATE ION, calcium/calmodulin-dependent protein kinase | | 著者 | Ozden, C, Abromson, N.L, Tomchick, D.R, Stratton, M.M, Garman, S.C. | | 登録日 | 2023-10-28 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Full-length human CaMKII delta holoenzyme
To be published
|
|
8VSW
 | | 4-MERCAPTOPHENOL-ALPHA3C | | 分子名称: | 4-mercaptophenol-alpha3C protein, 4-sulfanylphenol | | 著者 | Tommos, C. | | 登録日 | 2024-01-24 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Switching the proton-coupled electron transfer mechanism for non-canonical tyrosine residues in a de novo protein.
Chem Sci, 15, 2024
|
|
8W3V
 | | Crystal structure of human WDR41 | | 分子名称: | WD repeat-containing protein 41 | | 著者 | Hutchinson, A, Dong, A, Li, Y, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | 登録日 | 2024-02-22 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human WDR41
To be published
|
|
8V3B
 | |
8WUC
 | | Cryo-EM structure of H. thermoluteolus GroEL-GroES2 football complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | | 登録日 | 2023-10-20 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural insights into thermophilic chaperonin complexes.
Structure, 2024
|
|
8VJC
 | | Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | | 分子名称: | Insulin-like growth factor II, Isoform Short of Insulin receptor | | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | | 登録日 | 2024-01-06 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
|
|
8WUW
 | | Cryo-EM structure of H. thermophilus GroEL-GroES2 asymmetric football complex | | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | | 登録日 | 2023-10-21 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into thermophilic chaperonin complexes.
Structure, 2024
|
|
8WU4
 | | Cryo-EM structure of native H. thermoluteolus TH-1 GroEL | | 分子名称: | Chaperonin GroEL | | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | | 登録日 | 2023-10-20 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into thermophilic chaperonin complexes.
Structure, 2024
|
|
8WUX
 | | Cryo-EM structure of H. thermophilus GroEL-GroES bullet complex | | 分子名称: | Chaperonin GroEL, Co-chaperonin GroES, MAGNESIUM ION, ... | | 著者 | Liao, Z, Gopalasingam, C.C, Kameya, M, Gerle, C, Shigematsu, H, Ishii, M, Arakawa, T, Fushinobu, S. | | 登録日 | 2023-10-21 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into thermophilic chaperonin complexes.
Structure, 2024
|
|
8WU1
 | | Cryo-EM structure of CB1-beta-arrestin1 complex | | 分子名称: | Beta-arrestin-1, Cannabinoid receptor 1,Vasopressin V2 receptor, Fab30 heavy chain, ... | | 著者 | Liao, Y, Zhang, H, Shen, Q, Cai, C. | | 登録日 | 2023-10-19 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structure of CB1-beta-arrestin1 complex
to be published
|
|
8VJB
 | | Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation. | | 分子名称: | Insulin-like growth factor II, Isoform Short of Insulin receptor | | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | | 登録日 | 2024-01-06 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
|
|
8WQA
 | | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
|
|
8WQE
 | | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1) | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
|
|
8WQC
 | | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1 | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
|
|
